An allelic series for the chalcone synthase locus in Arabidopsis

Gene

Volumn 255, Issue 2, 2000, Pages 127-138

  Saslowsky, David E ^a   Dana, Christopher D ^a   Winkel Shirley, Brenda ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Flavonoid biosynthetic pathway; Transparent testa mutations

Indexed keywords

CHALCONE SYNTHASE; FLAVONOID GLYCOSIDE; MESSENGER RNA;

ALLELE; ARABIDOPSIS; ARTICLE; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME STABILITY; ENZYME STRUCTURE; GENE LOCUS; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; MUTANT; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA ANALYSIS; TEMPERATURE SENSITIVITY;

ACYLTRANSFERASES; ALLELES; ARABIDOPSIS; BIOFLAVONOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA, PLANT; INTRAMOLECULAR LYASES; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; RNA, PLANT; SEQUENCE ANALYSIS, DNA; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, NON-P.H.S.; TRANSCRIPTION, GENETIC;

ARABIDOPSIS;

EID: 0034687098     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00304-8     Document Type: Article

References (41)

1. Burbulis I.E., Iacobucci M., Shirley B.W. A null mutation in the first enzyme of flavonoid biosynthesis does not affect male fertility in Arabidopsis. Plant Cell. 8:1996;1013-1025.
2. Burbulis I.E., Winkel-Shirley B. Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway. Proc. Natl. Acad. Sci. USA. 96:1999;12929-12934.
3. Cain C., Saslowsky D., Walker R., Shirley B. Expression of chalcone synthase and chalcone isomerase proteins in Arabidopsis seedlings. Plant Mol. Biol. 35:1997;377-381.
4. Coen E.S., Carpenter R., Martin C. Transposable elements generate novel spatial patterns of gene expression in Antirrhinum majus. Cell. 47:1986;285-296.
5. Debeaujon I., Léon-Kloosterziel K.M., Koornneef M. Influence of the testa on seed dormancy, germination, and longevity in Arabidopsis. Plant Physiol. 122:2000;403-413.
6. Devic M., Guilleminot J., Debeaujon I., Bechtold N., Bensaude E., Koornneef M., Pelletier G., Delseny M. The BANYULS gene encodes a DFR-like protein and is a marker of early seed coat development. Plant J. 19:1999;387-398.
7. Dixon R.A., Steele C.L. Flavonoids and isoflavonoids - a gold mine for metabolic engineering. Trends Plant Sci. 4:1999;394-400.
8. Doyle J.J., Doyle J.L. Isolation of plant DNA from fresh tissue. Focus. 12:1990;13-15.
9. Ferrer J.L., Jez J.M., Bowman M.E., Dixon R.A., Noel J.P. Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis. Nat. Struct. Biol. 6:1999;775-784.
10. Gerats A.G.M., de Vlaming P., Maizonnier D. Recombination behaviour and gene transfer in Petunia hybrida after pollen irradiation. Mol. Gen. Genet. 198:1984;57-61.
11. Guex N., Peitsch M.C. SWISS-MODEL and the Swiss-PdbViewer: An environment for comparative protein modeling. Electrophoresis. 18:1997;2714-2723.
12. Hardeman K.J., Chandler V.L. Characterization of bz1 mutants isolated from mutator stocks with high and low numbers of Mu1 elements. Dev. Genet. 10:1989;460-472.
13. Howden R., Godsbrough P.B., Andersen C.R., Cobbett C.S. Cadmium-sensitive, cad1 mutants of Arabidopsis thaliana are phytochelatin deficient. Plant Physiol. 107:1995;1059-1066.
14. Jez J.M., Ferrer J.L., Bowman M.E., Dixon R.A., Noel J.P. Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry. 39:2000a;890-902.
15. Jez J.M., Bowman M.E., Dixon R.A., Noel J.P. Structure and mechanism of chalcone isomerase: an evolutionarily unique enzyme in plants. Nat. Struct. Biol. 2000b.
16. Koornneef M. Mutations affecting the testa color in Arabidopsis. Arabid. Inf. Serv. 28:1990;1-4.
17. Kreuzaler F., Ragg H., Heller W., Tesch R., Witt I., Hammer D., Hahlbrock K. Flavanone synthase from Petroselinum hortense. Eur. J. Biochem. 99:1979;89-96.
18. Kubasek W.L., Shirley B.W., McKillop A., Goodman H.M., Briggs W., Ausubel F.M. Regulation of flavonoid biosynthetic genes in germinating Arabidopsis seedlings. Plant Cell. 4:1992;1229-1236.
19. Landry L.G., Chapple C.C.S., Last R.L. Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage. Plant Physiol. 109:1995;1159-1166.
20. Lanz T., Tropf S., Marner F.J., Schröder J., Schröder G. The role of cysteines in polyketide synthases: site-directed mutagenesis of resveratrol and chalcone synthases, two key enzymes in different plant-specific pathways. J. Biol. Chem. 266:1991;9971-9976.
21. Larkin J.C., Walker J.D., Bolognesi-Winfield A.C., Gray J.C., Walker A.R. Allele-specific interactions between ttg and gl1 during trichome development in Arabidopsis thaliana. Genetics. 151:1999;1591-1604.
22. Li J., Ou-Lee T.M., Raba R., Amundson R.G., Last R.L. Arabidopsis flavonoid mutants are hypersensitive to UV-B irradiation. Plant Cell. 5:1993;171-179.
23. radialis. Plant Cell. 5:1993;1541-1553.
24. McNellis T.W., von Arnim A.G., Araki T., Komeda Y., Miséra S., Deng X.-W. Genetic and molecular analysis of an allelic series of cop1 mutants suggests functional roles for the multiple protein domains. Plant Cell. 6:1994;487-500.
25. Martin C., Lister C. Genome juggling by transposons: Tam3-induced rearrangements in Antirrhinum majus. Dev. Genet. 10:1989;438-451.
26. Mol J., Grotewold E., Koes R. How genes paint flowers and seeds. Trends Plant Sci. 3:1998;212-217.
27. Olsen O., Wang X., von Wettstein D. Sodium azide mutagenesis: Preferential generation of A·T→G·C transitions in the barley Ant18 gene. Proc. Natl. Acad. Sci. USA. 90:1993;8043-8047.
28. Pelletier M.K., Shirley B.W. Analysis of flavanone 3-hydroxylase in Arabidopsis seedlings. Coordinate regulation with chalcone synthase and chalcone isomerase. Plant Physiol. 111:1996;339-345.
29. Pelletier M.K., Murrell J.R., Shirley B.W. Characterization of flavonol synthase and leucoanthocyanidin dioxygenase genes in Arabidopsis. Plant Physiol. 113:1997;1437-1445.
30. Pelletier M.K., Burbulis I.E., Shirley B.W. Disruption of specific flavonoid genes enhances the accumulation of flavonoid enzymes and endproducts in Arabidopsis seedlings. Plant Mol. Biol. 40:1999;45-54.
31. Ralston E.J., English J.J., Dooner H.K. Sequence of three bronze alleles of maize and correlation with the genetic fine structure. Genetics. 119:1988;185-197.
32. Rose A.B., Li J., Last R.L. An allelic series of blue fluorescent trp1 mutants of Arabidopsis thaliana. Genetics. 145:1997;197-205.
33. Sali A., Blundell T.L. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234:1993;779-815.
34. Shirley B.W., Hanley S., Goodman H.M. Effects of ionizing radiation on a plant genome: analysis of two Arabidopsis transparent testa mutations. Plant Cell. 4:1992;333-347.
35. Shirley B.W., Kubasek W.L., Storz G., Bruggemann E., Koornneef M., Ausubel F.M., Goodman H.M. Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis. Plant J. 8:1995;659-671.
36. Shirley B.W. Flavonoid biosynthesis: 'new' functions for an 'old' pathway. Trends Plant Sci. 1:1996;377-382.
37. Todd J.J., Vodkin L.O. Duplications that suppress and deletions that restore expression from a chalcone synthase multigene family. Plant Cell. 8:1996;687-699.
38. Tropf S., Lanz T., Rensing S.A., Schröder G. Evidence that stilbene synthases have developed from chalcone synthases several times in the course of evolution. J. Mol. Evol. 38:1994;610-618.
39. Tropf S., Kärcher B., Schröder G., Schröder J. Reaction mechanisms of homodimeric plant polyketide synthases (stilbene and chalcone synthase). J. Biol. Chem. 270:1995;7922-7928.
40. Watson J.C., Thompson W.F. Purification and restriction endonuclease analysis of plant nuclear DNA. Meth. Enzymol. 118:1986;57-75.
41. Ylstra B., Muskens M., VanTunen A.J. Flavonols are not essential for fertilization in Arabidopsis thaliana. Plant Mol. Biol. 32:1996;1155-1158.