Synthesis and bioactivities of novel piperidylpyrimidine derivatives: Inhibitors of tumor necrosis factor-alpha production

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 12, 2000, Pages 1317-1320

  Fujiwara, Norio ^a   Fujita, Hitoshi ^a   Iwai, Kiyotaka ^a   Kurimoto, Ayumu ^a   Murata, Shinobu ^a   Kawakami, Hajime ^a  

^a DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

PIPERIDYLPYRIMIDINE DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINAZOLINE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SCREENING; DRUG STRUCTURE; INHIBITION KINETICS; MOUSE; NONHUMAN; PARTIAL DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; MICE; MOLECULAR STRUCTURE; PIPERIDINES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0034686571     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00227-4     Document Type: Article

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