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note
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13C NMR and FAB HMRS. Optical rotations have been measured for final compounds. All lactones exist as a 2:1 thermodynamic mixture of cis and trans isomers.
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18
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0343222311
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Synthon 5 (c.a. 2:1 E:Z ratio, ee 86%) has been prepared in 9 steps from 1,7-octadiene unpublished results
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Synthon 5 (c.a. 2:1 E:Z ratio, ee 86%) has been prepared in 9 steps from 1,7-octadiene (Warmerdam, E.; Rodier, S.; Renoux, B.; Gesson, J.-P. unpublished results).
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Warmerdam, E.1
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Gesson, J.-P.4
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