A model for Zn(II)-containing-β-lactamase: Synthesis, X-ray crystal structure of a Zinc(II) complex bearing thiol group and hydrolysis of phosphate diester

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 12, 2000, Pages 1333-1337

  Kurosaki, Hiromasa ^a   Tawada, Toshiaki ^a   Kawasoe, Satomi ^a   Ohashi, Yoko ^a   Goto, Masafumi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; NITROCEFIN; ORGANOPHOSPHATE; ZINC COMPLEX; ESTER; THIOL DERIVATIVE; ZINC;

ARTICLE; BACILLUS CEREUS; CHEMICAL MODIFICATION; DRUG DESIGN; DRUG HYDROLYSIS; DRUG STRUCTURE; NONHUMAN; PARTIAL DRUG SYNTHESIS; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY; CHEMICAL MODEL; CHEMISTRY; HYDROLYSIS; KINETICS; PH; PROTEIN CONFORMATION; SYNTHESIS;

BETA-LACTAMASES; CRYSTALLOGRAPHY, X-RAY; ESTERS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MODELS, CHEMICAL; PROTEIN CONFORMATION; SULFHYDRYL COMPOUNDS; ZINC;

EID: 0034686093     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00238-9     Document Type: Article

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