Jak2 acts as both a STAT1 kinase and as a molecular bridge linking STAT1 to the angiotensin II AT1 receptor

Journal of Biological Chemistry

Volumn 275, Issue 20, 2000, Pages 15586-15593

  Ali, M Showkat ^a   Sayeski, Peter P ^a   Bernstein, Kenneth E ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN 2 RECEPTOR; PROTEIN TYROSINE KINASE; STAT1 PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; ANGIOTENSIN II; ANIMALS; CHO CELLS; COS CELLS; CRICETINAE; DNA-BINDING PROTEINS; JANUS KINASE 2; KINETICS; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RATS; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION; TYROSINE;

ANIMALIA;

EID: 0034686082     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M908931199     Document Type: Article

References (31)

1. Gibbons, G. H., Pratt, R., and Dzau, V. J. (1992) J. Clin. Invest. 90, 456-461
2. Dzau, V. J. (1987) J. Cardiovasc. Pharmacol. 10, S9-S16
3. Timmermans, P. B., Wong, P. C., Chiu, A. T., and Herblin, W. F. (1991) Trends Pharmacol. Sci. 12, 55-62
4. Timmermans, P. B., Wong, P. C., Chiu, A. T., Herblin, W. F., Benfield, P., Carini, D. J., Lee, R. J., Wexler, R. R., Saye, J. A. M., and Smith, R. D. (1993) Pharmacol. Rev. 45, 205-251
5. Marrero, M. B., Schieffer, B., Paxton, W. G., Heerdt, L., Berk, B. C., Delafontaine, P., and Bernstein, K. E. (1995) Nature 375, 247-250
6. Bhat, G. J. Thekkumkara, T. J., Thomas, W. G., Conrad, K. M., and Baker, K. M. (1994) J. Biol. Chem. 269, 31443-31449
7. Schindler, C. (1995) Annu. Rev. Biochem. 64, 621-651
8. Ihle, J. N., Witthuln, B. A., Quelle, F. W., Yamamoto, K., Thierfelder, W. E., Kreider, B., and Silvennoinen, O. (1994) Trends Biochem. Sci. 19, 222-227
9. Leonard, W. J., and O'Shea, J. J. (1998) Annu. Rev. Immunol. 16, 293-322
10. Charlene, D. M., Rachel, A. H., Kathleen, M. C., David, E. D., and Baker, K. M. (1997) J. Mol. Cordiol. 29, 2513-2524
11. Greenlund, A. C., Farrar, M. A., Viviano, B. L., and Schreibeer, R. D. (1994) EMBO J. 13, 1591-1600
12. Novak, K., Nice, E., Hamilton, J. A., and Pradisol, L. (1996) Oncogene 13, 2607-2613
13. Gupta, S., Yan, H., Wong, L. H., Ralph, S., Krolewske, J. J., and Schindler, C. W. (1996) EMBO J. 15, 1075-1084
14. Oppermann, M., Freedman, N. J., Alexander, R. W., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 13266-13272
15. Zhuang, H., Patel, S. V., He, T., Sonsteby, S. K., Niu, Z., and Wojchowski, D. M. (1994) J. Biol. Chem. 269, 21411-21414
16. Ali, M. S., Sayeski, P. P., Dirksen, L. B., Hayzer, D. J., Marrero, M. B., and Bernstein, K. E. (1997) J. Biol. Chem. 272, 23382-23388
17. Murphy, T. J., Alexander, R. W., Griendling, K. K., Runge, M. S., and Bernstein, K. E. (1991) Nature 351, 233-236
18. Bhat, G. J., Thekkumkara, T. J., Thomas, W. G., Conrad, K. M., and Baker, K. M. (1995) J. Biol. Chem. 270, 19059-19065
19. Harpur, A. G., Andrews, A.-C., Ziemiecki, A., Aston, R. R., and Wilks, F. F. (1992) Oncogene 7, 1347-1353
20. Paxton, W. G., Marrero, M. B., Klein, J. D., Delafontaine, P., Berk, B. C., and Bernstein, K. E. (1994) Biochem. Biophys. Res. Commun. 200, 260-267
21. Sayeski, P. P., Ali, M. S., Semeniuk, D. J., Doan, T. N., and Bernstein, K. E. (1998) Reg. Peptides 78, 19-29
22. Ihle, J. N. (1996) Cell 84, 331-334
23. Feng, J. B., Whitthuhn, A., Matsuda, T., Kohlhuber, F., Kerr, I. M., and Ihle, J. N. (1997) Mol. Cell. Biol. 17, 2497-2501
24. Smit, L. S., Meyer, D. J., Billestrup, N., Norstedt, G., Schwartz, J., and Carter-Su, C. (1996) Mol. Endocrinol. 5, 519-533
25. Stahl, N., Farruggel, T. J., Boulton, T. G., Zhong, Z., Darnell, J. E., Jr., and Yancopoulos, G. D. (1995) Science 267, 1349-1353
26. Wakao, H., Harada, H., Kitamura, T., Mui, A. L., and Miyajima A. (1995) EMBO J. 14, 2527-2535
27. Wang, Y.-D., Wong, K., and Wood, W. I. (1995) J. Biol. Chem. 270, 7021-7024
28. David, M., Wong, L., Flavell, R., Thompson, S. A., Wells, A., Larner, A. C., and Johnson, G. R. (1996) J. Biol. Chem. 271, 9185-9188
29. Yoshikawa, A., Murakami, H., and Nagata, S. (1995) EMBO J. 14, 5288-5296
30. DaSilva, L., Ru Herwin, R. A., Howard, D. M. Z., Kirken, R. A., Malabarba, M. G., Hackett, R. H., Larner, A. C., and Farrar, W. L. (1996) Mol. Cell. Endocrinol. 117, 131-140
31. Fujitani, Y., Hibi, M., Fukada, T., Takahashitezuka, M., Yoshida, H., Yamaguchi, T., Sugiyama, K., Yamanaka, Y., Nakajima, K., and Hirano, T. (1997) Oncogene 14, 751-761