Determination of the solution conformation of D-gluco-dihydroacarbose, a high-affinity inhibitor bound to glucoamylase by transferred NOE NMR spectroscopy

Carbohydrate Research

Volumn 326, Issue 1, 2000, Pages 50-55

  Weimar, Thomas ^a   Petersen, Bent O ^b   Svensson, Birte ^b   Pinto, B Mario ^c  

^a UNIVERSITY OF LÜBECK   (Germany)

^b CARLSBERG LABORATORY   (Denmark)

^c SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Bound conformation; D Gluco dihydroacarbose; Glucoamylase; Glycosidase inhibitor; Transferred NOE NMR spectroscopy

Indexed keywords

ACARBOSE; GLUCAN 1,4 ALPHA GLUCOSIDASE; GLUCOSE DERIVATIVE;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; CARBOHYDRATE ANALYSIS; COMPLEX FORMATION; CONFORMATION; CRYSTAL STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

CARBOHYDRATE CONFORMATION; CARBOHYDRATE SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; GLUCAN 1,4-ALPHA-GLUCOSIDASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; TRISACCHARIDES;

EID: 0034685673     PISSN: 00086215     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6215(00)00021-5     Document Type: Article

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