A selective inhibitor of p38 MAP kinase, SB202190, induced apoptotic cell death of a lipopolysaccharide-treated macrophage-like cell line, J774.1

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1502, Issue 2, 2000, Pages 207-223

  Karahashi, Hisae ^a   Nagata, Kazuhiro ^b   Ishii, Kumiko ^a   Amano, Fumio ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase 3; Erk; JNK; p38 MAP kinase phosphorylation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 ETHYL 2 (4 METHOXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CASPASE 3; HEAT SHOCK PROTEIN 27; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; POLYMYXIN B; SYNAPTOPHYSIN; TOSYLPHENYLALANYL CHLOROMETHYL KETONE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; IN VITRO STUDY; MACROPHAGE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMAL; APOPTOSIS; CASPASES; CELL LINE; ENZYME ACTIVATION; ENZYME INHIBITORS; IMIDAZOLES; IN SITU NICK-END LABELING; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM PROTEINS; PHOSPHORYLATION; PYRIDINES; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T;

EID: 0034684281     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(00)00045-4     Document Type: Article

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