Tegumental changes in adult Schistosoma mansoni harboured in mice treated with praziquantel enantiomers

Acta Tropica

Volumn 76, Issue 2, 2000, Pages 107-117

  Shuhua, Xiao ^a   Binggui, Shen ^a   Chollet, Jacques ^b   Tanner, Marcel ^b  

^a CHINESE CENTER FOR DISEASE CONTROL AND PREVENTION   (China)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

Enantiomers; Praziquantel; Scanning electron microscopy; Schistosoma mansoni; Schistosomiasis

Indexed keywords

PRAZIQUANTEL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; ENANTIOMER; FEMALE; MORPHOMETRICS; MOUSE; NONHUMAN; SCANNING ELECTRON MICROSCOPY; SCHISTOSOMA MANSONI; WORM TEGUMENT;

ANIMALS; ANTHELMINTICS; FEMALE; MALE; MICE; MICROSCOPY, ELECTRON, SCANNING; OPTICAL ROTATION; PRAZIQUANTEL; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; STEREOISOMERISM;

ANIMALIA; SCHISTOSOMA MANSONI; TREMATODA;

EID: 0034684054     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0001-706X(00)00076-0     Document Type: Article

References (15)

1. Andrews P., Thomas H., Pohlke R., Seubert J. Praziquantel. Med. Res. Rev. 3:1983;147-200.
2. Andrews P. Praziquantel: mechanisms of anti-schistosomal activity. Pharmacol. Ther. 29:1985;129-156.
3. Irie Y., Utsunomiya H., Tanaka M., Ohmae H., Nara T., Yasuraoka K. Schistosoma japonicum and S. mansoni: ultrastructural damage in the tegument and reproductive organs after treatment with levo- and dextro-praziquantel. Am. J. Trop. Med. Hyg. 41:1989;204-211.
4. Liu Y.H., Qian M.X., Wang X.G., Wang R.Q., Lu S.Z., Liu J., Li G.H., Chen Y.D. Efficacy of single oral doses of praziquantel in treatment of Schistosoma japonicum infection. Chin. Med. J. 99:1986a;470-472.
5. Liu Y.H., Qian M.X., Wang X.G., Jia J., Wang Q.N., Jiang Y.F., Wang R.Q., Yan S.H., Chen B.Y., Li J.S. Comparative efficacy of praziquantel and its optic isomers in experimental therapy of schistosomiasis in rabbits. Chin. Med. J. 99:1986b;935-940.
6. Liu Y.H., Wang X.G., Qian M.X., Yan S.H., Chen B.Y., Li J.S., Jin J.M., Zhang G.S. A comparative trial of single dose treatment with praziquantel and levopraziquantel in human schistosomiasis japonica. Jap. J. Parasitol. 37:1988;331-334.
7. Staudt U., Schmahl G., Blaschke G., Mehlhorn H. Light and scanning electron microscopy studies on the effects of the enantiomers of praziquantel and its main metabolite on Schistosoma mansoni in vitro. Parasitol. Res. 78:1992;392-397.
8. Tanaka M., Ohmae H., Utsunomiya H., Nara T., Irie Y., Yasuraoka K. A comparison of the antischistosomal effect of levo- and dextro-praziquantel on Schistosoma japonicum and S. mansoni in mice. Am. J. Trop. Med. Hyg. 41:1989;198-203.
9. Wang X.G., Liu Y.H., Tan S.H., Yan S.H., Chen B.Y., Qian M.X., Zheng X.P., Wang Q.N. Comparative efficacy of levopraziquantel and praziquantel in the treatment of Schistosoma japonicum infection. Acta Univer. Sci. Med. Chongquine. 12:1987;9-12.
10. Wu M.H., Wei C.C., Xu Z.Y., Yuan H.C., Lian W.N., Yang Q.J., Chen M., Jiang Q.Q., Wang C.Z., Zhang S.J. Comparison of the therapeutic efficacy and side effects of a single dose of levo-praziquantel with mixed isomer praziquantel in 278 cases of schistosomiasis japonica. Am. J. Trop. Med. Hyg. 45:1991;345-349.
11. Xiao S.H., Dai Z.Q., Zhang R.Q., Xu H.C., Shao B.R. Scanning electron microscope observation on tegumental surface alterations of Schistosoma japonicum induced by pyquiton. Acta Pharm. Sin. 17:1982;498-502.
12. Xiao S.H., Catto B.A. Comparative in vitro and in vivo activity of racemic praziquantel and its levorotated isomer on Schistosoma mansoni. J. Infect. Dis. 159:1989;589-592.
13. Xiao S.H., Shen B.G. Scanning electron microscope observation on tegumental alteration of Schistosoma japonicum induced by levo- and dextro-praziquantel. Chin. J. Parasitol. Parasitic Dis. 13:1995;46-50.
14. Xiao S.H., You J.Q., Mei J.Y., Hu Y.Q., Zhou D.H., Catto B.A. In vitro and in vivo effect of levopraziquantel, dextropraziquantel versus racemic praziquantel on different developmental stages of Schistosoma japonicum. Chin. J. Parasitol. Parasitic Dis. 16:1998;335-341.
15. Xiao S., Chollet J., Booth M., Weiss N.A., Tanner M. Therapeutic effect of praziquantel enantiomers in mice infected with Schistosoma mansoni. Trans. Roy. Soc. Trop. Med. Hyg. 93:1999;324-325.