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Volumn 2, Issue 10, 2000, Pages 1439-1442

Synthesis of the apoptosis inducing agent apoptolidin. Assembly of the C(16)-C(28) fragment

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTINEOPLASTIC ANTIBIOTIC; APOPTOLIDIN; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; MACROLIDE;

EID: 0034682173     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol005769v     Document Type: Article
Times cited : (51)

References (34)
  • 18
    • 85037518799 scopus 로고    scopus 로고
    • All new compounds gave characterization data that are fully consistent with the assigned structures
    • All new compounds gave characterization data that are fully consistent with the assigned structures.
  • 29
    • 85037514676 scopus 로고    scopus 로고
    • note
    • In Crimmins' original report (ref 5), Hunig's base provided superior selectivity in the non-Evans aldol reaction manifold; in the case of 16 we found that Hunig's base led to diminished chemical yield. In contrast (-)-sparteine provided both high stereoselectivity and chemical yield.
  • 30
    • 85037505399 scopus 로고    scopus 로고
    • See Supporting Information
    • See Supporting Information.
  • 31
    • 49349137641 scopus 로고
    • (a) Basha, A.; Lipton, M.; Weibreb, S. M. Tetrahedron Lett. 1977, 4171-4174. As in the case of oxazolidinones, the order of transamination and beta hydroxy protection is important, see: (b) Evans, D. A.; Gage, J. R.; Leighton, J. L. J. Am. Chem. Soc. 1992, 114, 9434-9453.
    • (1977) Tetrahedron Lett. , pp. 4171-4174
    • Basha, A.1    Lipton, M.2    Weibreb, S.M.3
  • 32
    • 0027050190 scopus 로고
    • (a) Basha, A.; Lipton, M.; Weibreb, S. M. Tetrahedron Lett. 1977, 4171-4174. As in the case of oxazolidinones, the order of transamination and beta hydroxy protection is important, see: (b) Evans, D. A.; Gage, J. R.; Leighton, J. L. J. Am. Chem. Soc. 1992, 114, 9434-9453.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 9434-9453
    • Evans, D.A.1    Gage, J.R.2    Leighton, J.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.