-
1
-
-
9844260513
-
Syntheses and biological activity (topoisomerases inhibition, antitumoral and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group
-
Anizon F., Belin L., Moreau P., Sancelme M., Voldoire A., Prudhomme M., Ollier M., Sevère D., Riou J.F., Bailly C., Fabro D., Meyer T. Syntheses and biological activity (topoisomerases inhibition, antitumoral and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group. J. Med. Chem. 40:1997;3456-3465.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 3456-3465
-
-
Anizon, F.1
Belin, L.2
Moreau, P.3
Sancelme, M.4
Voldoire, A.5
Prudhomme, M.6
Ollier, M.7
Sevère, D.8
Riou, J.F.9
Bailly, C.10
Fabro, D.11
Meyer, T.12
-
2
-
-
0028905348
-
Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7-(6H)-dione (NB-506): Its potent antitumor activities in mice
-
Arakawa H., Iguchi T., Morita M., Yoshinari T., Kojiri K., Suda H., Okura A., Nishimura S. Novel indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7-(6H)-dione (NB-506): its potent antitumor activities in mice. Cancer Res. 55:1995;1316-1320.
-
(1995)
Cancer Res.
, vol.55
, pp. 1316-1320
-
-
Arakawa, H.1
Iguchi, T.2
Morita, M.3
Yoshinari, T.4
Kojiri, K.5
Suda, H.6
Okura, A.7
Nishimura, S.8
-
3
-
-
0033529311
-
The camptothecin-resistant topoisomerase I mutant F361S is cross-resistant to antitumor rebeccamycin derivatives
-
Bailly C., Carrasco C., Hamy F., Vezin H., Prudhomme M., Saleem A., Rubin E. The camptothecin-resistant topoisomerase I mutant F361S is cross-resistant to antitumor rebeccamycin derivatives. Biochemistry. 38:1999;8605-8611.
-
(1999)
Biochemistry
, vol.38
, pp. 8605-8611
-
-
Bailly, C.1
Carrasco, C.2
Hamy, F.3
Vezin, H.4
Prudhomme, M.5
Saleem, A.6
Rubin, E.7
-
4
-
-
0031938920
-
Recognition of specific sequences in DNA by a topoisomerase I inhibitor derived from the antitumor drug rebeccamycin
-
Bailly C., Colson P., Houssier C., Rodrigues-Pereira E., Prudhomme M., Waring M.J. Recognition of specific sequences in DNA by a topoisomerase I inhibitor derived from the antitumor drug rebeccamycin. Mol. Pharmacol. 53:1998;77-87.
-
(1998)
Mol. Pharmacol.
, vol.53
, pp. 77-87
-
-
Bailly, C.1
Colson, P.2
Houssier, C.3
Rodrigues-Pereira, E.4
Prudhomme, M.5
Waring, M.J.6
-
5
-
-
0033133944
-
Calories from carbohydrates. Energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition
-
Bailly C., Qu X., Graves D.E., Chaires J.B. Calories from carbohydrates. Energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibition. Chem. Biol. 6:1999;277-286.
-
(1999)
Chem. Biol.
, vol.6
, pp. 277-286
-
-
Bailly, C.1
Qu, X.2
Graves, D.E.3
Chaires, J.B.4
-
6
-
-
0030944043
-
DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin
-
Bailly C., Riou J.F., Colson P., Houssier C., Rodrigues-Pereira E., Prudhomme M. DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin. Biochemistry. 36:1997;3917-3929.
-
(1997)
Biochemistry
, vol.36
, pp. 3917-3929
-
-
Bailly, C.1
Riou, J.F.2
Colson, P.3
Houssier, C.4
Rodrigues-Pereira, E.5
Prudhomme, M.6
-
7
-
-
0023103573
-
Membrane transport of mitoxantrone by L1210 leukemia cells
-
Burns C.P., Haugstad B.N., North J.A. Membrane transport of mitoxantrone by L1210 leukemia cells. Biochem. Pharmacol. 36:1987;857-860.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 857-860
-
-
Burns, C.P.1
Haugstad, B.N.2
North, J.A.3
-
8
-
-
0027065565
-
Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor
-
Casieri M.A., Ber E., Fong T.M., Sadowski S., Bansal A., Swain C., Saward E., Frances B., Burns D., Strader C.D. Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor. Mol. Pharmacol. 42:1992;458-463.
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 458-463
-
-
Casieri, M.A.1
Ber, E.2
Fong, T.M.3
Sadowski, S.4
Bansal, A.5
Swain, C.6
Saward, E.7
Frances, B.8
Burns, D.9
Strader, C.D.10
-
9
-
-
0032893999
-
Poisoning of topoisomerase I by an antitumor indolocarbazole drug: Stabilization of topoisomerase I-DNA covalent complexes and specific inhibition of the protein kinase activity
-
Labourier E., Riou J.F., Prudhomme M., Carrasco C., Bailly C., Tazi J. Poisoning of topoisomerase I by an antitumor indolocarbazole drug: stabilization of topoisomerase I-DNA covalent complexes and specific inhibition of the protein kinase activity. Cancer Res. 59:1999;52-55.
-
(1999)
Cancer Res.
, vol.59
, pp. 52-55
-
-
Labourier, E.1
Riou, J.F.2
Prudhomme, M.3
Carrasco, C.4
Bailly, C.5
Tazi, J.6
-
10
-
-
0027472338
-
Sequential modifications of topoisomerase I activity in a camptothecin resistant cell line established by progressive adaptation
-
Madelaine J., Prost S., Naudin A., Riou G., Lavelle F., Riou J.F. Sequential modifications of topoisomerase I activity in a camptothecin resistant cell line established by progressive adaptation. Biochem. Pharmacol. 45:1993;339-348.
-
(1993)
Biochem. Pharmacol.
, vol.45
, pp. 339-348
-
-
Madelaine, J.1
Prost, S.2
Naudin, A.3
Riou, G.4
Lavelle, F.5
Riou, J.F.6
-
11
-
-
15144351325
-
Syntheses and biological evaluation of indolocarbazoles, analogues of rebeccamycin, modified at the imide heterocycle
-
Moreau P., Anizon F., Sancelme M., Prudhomme M., Bailly C., Carrasco C., Ollier M., Sevère D., Riou J.F., Fabro D., Meyer T., Aubertin A.M. Syntheses and biological evaluation of indolocarbazoles, analogues of rebeccamycin, modified at the imide heterocycle. J. Med. Chem. 41:1998;1631-1640.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 1631-1640
-
-
Moreau, P.1
Anizon, F.2
Sancelme, M.3
Prudhomme, M.4
Bailly, C.5
Carrasco, C.6
Ollier, M.7
Sevère, D.8
Riou, J.F.9
Fabro, D.10
Meyer, T.11
Aubertin, A.M.12
-
12
-
-
0033602140
-
Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent
-
Moreau P., Anizon F., Sancelme M., Prudhomme M., Bailly C., Ollier M., Sevère D., Riou J.F., Fabbro D., Meyer T., Aubertin A.M. Syntheses and biological activities of rebeccamycin analogues. Introduction of a halogenoacetyl substituent. J. Med. Chem. 42:1999;584-592.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 584-592
-
-
Moreau, P.1
Anizon, F.2
Sancelme, M.3
Prudhomme, M.4
Bailly, C.5
Ollier, M.6
Sevère, D.7
Riou, J.F.8
Fabbro, D.9
Meyer, T.10
Aubertin, A.M.11
-
13
-
-
0033587125
-
Synthesis, mode of action and biological activities of rebeccamycin bromo-derivatives
-
Moreau P., Anizon F., Sancelme M., Prudhomme M., Sevère D., Riou J.F., Goossens J.F., Hénichart J.P., Bailly C., Labourier E., Tazi J., Fabbro D., Meyer T., Aubertin A.M. Synthesis, mode of action and biological activities of rebeccamycin bromo-derivatives. J. Med. Chem. 42:1999;1816-1822.
-
(1999)
J. Med. Chem.
, vol.42
, pp. 1816-1822
-
-
Moreau, P.1
Anizon, F.2
Sancelme, M.3
Prudhomme, M.4
Sevère, D.5
Riou, J.F.6
Goossens, J.F.7
Hénichart, J.P.8
Bailly, C.9
Labourier, E.10
Tazi, J.11
Fabbro, D.12
Meyer, T.13
Aubertin, A.M.14
-
14
-
-
0022578537
-
Evidence that the antitumor agent hydroxyurea enters mammalian cells by a diffusion mechanism
-
Morgan J.S., Creasey D.C., Wright J.A. Evidence that the antitumor agent hydroxyurea enters mammalian cells by a diffusion mechanism. Biochem. Biophys. Res. Commun. 134:1986;1254-1259.
-
(1986)
Biochem. Biophys. Res. Commun.
, vol.134
, pp. 1254-1259
-
-
Morgan, J.S.1
Creasey, D.C.2
Wright, J.A.3
-
15
-
-
0003267271
-
Phase I and pharmacology study of 5-day infusion of NB-506
-
Ohe Y., Tanigawara Y., Fujii H., Ohtsu T., Wakita H., Igarashi T., Minami H., Eguchi K., Shinkai T., Tamura T., Kunotoh H., Saijo N., Okada K., Ogino H., Sasaki Y. Phase I and pharmacology study of 5-day infusion of NB-506. Proc. ACSO. 16:1997;199a.
-
(1997)
Proc. ACSO
, vol.16
-
-
Ohe, Y.1
Tanigawara, Y.2
Fujii, H.3
Ohtsu, T.4
Wakita, H.5
Igarashi, T.6
Minami, H.7
Eguchi, K.8
Shinkai, T.9
Tamura, T.10
Kunotoh, H.11
Saijo, N.12
Okada, K.13
Ogino, H.14
Sasaki, Y.15
-
16
-
-
0032936474
-
Advances in indolo[2,3-a]carbazole chemistry: Design synthesis of protein kinase C and topoisomerase I inhibitors
-
Pindur U., Kim Y.-S., Mehrabani F. Advances in indolo[2,3-a]carbazole chemistry: design synthesis of protein kinase C and topoisomerase I inhibitors. Curr. Med. Chem. 6:1999;29-69.
-
(1999)
Curr. Med. Chem.
, vol.6
, pp. 29-69
-
-
Pindur, U.1
Kim, Y.-S.2
Mehrabani, F.3
-
17
-
-
0030762374
-
Indolocarbazoles as anti-cancer agents
-
Prudhomme M. Indolocarbazoles as anti-cancer agents. Curr. Pharm. Des. 3:1997;265-290.
-
(1997)
Curr. Pharm. Des.
, vol.3
, pp. 265-290
-
-
Prudhomme, M.1
-
18
-
-
0000714445
-
Structure-activity relationships in a series of substituted indolocarbazoles: Topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties
-
Rodrigues-Pereira E., Belin L., Sancelme M., Prudhomme M., Ollier M., Rapp M., Servère D., Riou J.F., Fabbro D. Structure-activity relationships in a series of substituted indolocarbazoles: topoisomerase I and protein kinase C inhibition and antitumoral and antimicrobial properties. J. Med. Chem. 39:1996;4471-4477.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 4471-4477
-
-
Rodrigues-Pereira, E.1
Belin, L.2
Sancelme, M.3
Prudhomme, M.4
Ollier, M.5
Rapp, M.6
Servère, D.7
Riou, J.F.8
Fabbro, D.9
-
19
-
-
0031965431
-
New chemotherapeutic agents for the treatment of non-small cell lung cancer
-
Saijo N. New chemotherapeutic agents for the treatment of non-small cell lung cancer. Chest. 113:1998;17S-23S.
-
(1998)
Chest
, vol.113
-
-
Saijo, N.1
-
20
-
-
0026678588
-
Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives
-
Yamashita Y., Fujii N., Murakata C., Ashizawa T., Okabe M., Nakano H. Induction of mammalian DNA topoisomerase I mediated DNA cleavage by antitumor indolocarbazole derivatives. Biochemistry. 31:1992;12069-12075.
-
(1992)
Biochemistry
, vol.31
, pp. 12069-12075
-
-
Yamashita, Y.1
Fujii, N.2
Murakata, C.3
Ashizawa, T.4
Okabe, M.5
Nakano, H.6
-
21
-
-
0028931509
-
Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7-(6H)-dione (NB-506): Induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity
-
Yoshinari T., Matsumoto M., Arakawa H., Okada H., Noguchi K., Suda H., Okura A., Nishimura S. Novel antitumor indolocarbazole compound 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo-[3,4-c]carbazole-5,7-(6H)-dione (NB-506): induction of topoisomerase I-mediated DNA cleavage and mechanisms of cell line-selective cytotoxicity. Cancer Res. 55:1995;1310-1315.
-
(1995)
Cancer Res.
, vol.55
, pp. 1310-1315
-
-
Yoshinari, T.1
Matsumoto, M.2
Arakawa, H.3
Okada, H.4
Noguchi, K.5
Suda, H.6
Okura, A.7
Nishimura, S.8
-
22
-
-
0027461273
-
Induction of topoisomerase I-mediated DNA cleavage by a new indolocarbazole, ED-110
-
Yoshinari T., Yamada A., Uemura D., Nomura K., Arakawa H., Kojiri K., Yoshida E., Suda H., Okura A. Induction of topoisomerase I-mediated DNA cleavage by a new indolocarbazole, ED-110. Cancer Res. 53:1993;490-494.
-
(1993)
Cancer Res.
, vol.53
, pp. 490-494
-
-
Yoshinari, T.1
Yamada, A.2
Uemura, D.3
Nomura, K.4
Arakawa, H.5
Kojiri, K.6
Yoshida, E.7
Suda, H.8
Okura, A.9
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