SCOPUS 정보 검색 플랫폼

Volumn 65, Issue 23, 2000, Pages 7718-7722

Efficient pyridinylmethyl functionalization: Synthesis of 10,10-bis[(2-fluoro-4-pyridinyl)methyl]-9(10H)-anthracenone (DMP 543), an acetylcholine release enhancing agent

(6) Pesti, J A a Huhn, G F b Yin, J a Xing, Y a Fortunak, J M a Earl, R A a

a DUPONT COMPANY (United States)

b Decision Sight Inc (United States)

Author keywords

[No Author keywords available]

Indexed keywords

10,10 BIS(2 FLUORO 4 PYRIDINYLMETHYL) 9(10H) ANTHRACENONE; ACETYLCHOLINE; PICOLINE DERIVATIVE; PYRIDINE DERIVATIVE;

ACETYLCHOLINE RELEASE; ALKYLATION; ARTICLE; CHEMICAL MODIFICATION; CHLORINATION; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS;

ACETYLCHOLINE; ALZHEIMER DISEASE; ANTHRACENES; HUMANS;

EID: 0034680560 PISSN: 00223263 EISSN: None Source Type: Journal
DOI: 10.1021/jo9804339 Document Type: Article

Times cited : (12)

References (52)

1
- 0028332699
- (1994) Alzheimer Dis. Assoc. Disord. , vol.8 , Issue.SUPPL. 2
- Farlow, M.R.¹

2
- 0006912336
- (1997) Drug Market Dev. , vol.8 , pp. 229-235
- Davidson, B.¹

3
- 0030049889
- (1996) Drugs Aging , vol.8 , pp. 47-55
- Hollister, L.¹ Gruber, N.²

4
- 0029740824
- (1996) Bioorg. Med. Chem. Lett. , vol.4 , pp. 1429-1445
- Kawakami, Y.¹ Inoue, A.² Kawai, T.³ Wakita, M.⁴ Sugimoto, H.⁵ Hopfinger, A.J.⁶

5
- 84888103594
- (1997) Chem. Eng. News , vol.75 , pp. 29-35
- Brennan, M.B.¹

6
- 0025216441
- (1990) Drug Dev. Res. , vol.19 , pp. 285-300
- Nickolson, V.J.¹ Tam, S.W.² Myers, M.J.³ Cook, L.⁴

7
- 0025220350
- (1990) Drug Dev. Res. , vol.19 , pp. 301-314
- Cook, L.¹ Nickolson, V.J.² Steinfels, G.F.³ Rohrbach, K.W.⁴ Denoble, V.J.⁵

8
- 0029592066
- (1995) Drugs Future , vol.20 , pp. 1145-1162
- Chorvat, R.J.¹ Earl, R.A.² Zaczek, R.³

9
- 0006950920
- (1994) Alzheimer Dis. , pp. 252-255
- Zaczek, R.¹ Chorvat, R.J.² Earl, R.A.³ Tam, S.W.⁴

10
- 0026668012
- (1992) Bioorg. Med. Chem. Lett. , vol.2 , pp. 851-854
- Earl, R.A.¹ Myers, M.J.² Johnson, A.L.³ Scribner, R.M.⁴ Wuonola, M.A.⁵ Boswell, G.A.⁶ Wilkerson, W.W.⁷ Nickolson, V.J.⁸ Tam, S.W.⁹ Brittelli, D.R.¹⁰ Chorvat, R.J.¹¹ Zaczek, R.¹² Cook, L.¹³ Wang, C.¹⁴ Zhang, X.¹⁵ Lan, R.¹⁶ Mi, B.¹⁷ Wenting, H.¹⁸

11
- 0006950921
- Int. Pat. 1994, 241131
- (1995) Chem. Abstr. , vol.122 , pp. 105859
- Teleha, C.A.¹ Wilkerson, W.W.² Earl, R.A.³

12
- 0031809240
- (1998) J. Pharm. Exp. Ther. , vol.285 , pp. 724-730
- Zaczek, R.¹ Chorvat, R.J.² Saye, J.A.³ Pierdomenico, M.E.⁴ Maciag, C.M.⁵ Logue, A.R.⁶ Fisher, B.N.⁷ Rominger, D.H.⁸ Earl, R.A.⁹

13
- 15444350005
- (1998) J. Med. Chem. , vol.41 , pp. 4615-4622
- Earl, R.A.¹ Zaczek, R.² Teleha, C.A.³ Fisher, B.N.⁴ Maciag, C.M.⁵ Marynowski, M.E.⁶ Logue, A.R.⁷ Tam, S.W.⁸ Tinker, W.J.⁹ Huang, S.M.¹⁰ Chorvat, R.J.¹¹

14
- 0006911222
- unpublished research
- Earl, R.A.¹

15
- 0006988142
- (1963) Angew. Chem., Int. Ed. Engl. , vol.2 , pp. 144-149
- Mathes, W.¹ Schuly, H.²

16
- 0000677852
- (1982) J. Org. Chem. , vol.47 , pp. 4116-4120
- Newkome, G.R.¹ Puckett, W.E.² Kiefer, G.E.³ Gupta, V.K.⁴ Xia, Y.⁵ Coreil, M.⁶ Hackney, M.A.⁷

17
- 0006911055
- Eur. Pat. Appl. 557 967 A1
- (1994) Chem. Abstr. , vol.120 , pp. 30680
- Nishimura, Y.¹ Itou, Y.² Morino, A.³ Nishihara, K.⁴ Kawamura, S.⁵

18
- 0006955919
- (1951) J. Chem. Soc. , pp. 1145-1149
- Brown, B.R.¹ Hammick, D.L.² Thewlis, B.H.³

19
- 0006911056
- US Pat. 1993 5,198,549
- (1992) Chem. Abstr. , vol.116 , pp. 83696
- Gunther, A.¹

20
- 84986473633
- (1984) Synthesis , pp. 676-679
- Newkome, G.R.¹ Kiefer, G.E.² Xia, Y.-J.³

21
- 0006947246
- (1984) J. Org. Chem. , vol.49 , pp. 1286-1288
- Vaz, A.D.N.¹ Schoellmann, G.²

22
- 0025241162
- (1990) Tetrahedran , vol.46 , pp. 8103-8116
- Vilsmaier, E.¹ Dorrenbacher, R.² Muller, L.³

23
- 85027475376
- (1959) Bull. Soc. Chem. Belg. , vol.59 , pp. 193-207
- Hebbelynck, M.F.¹ Martin, R.H.²

24
- 0000185119
- (1953) Nature , vol.171 , pp. 704-705
- Adam, J.¹ Gosselain, P.A.² Goldfinger, P.³

25
- 0027407482
- (1993) Synthesis , pp. 237-241
- Bovonsombat, P.¹ McNelis, E.²

26
- 0001235190
- (1995) J. Org. Chem. , vol.60 , pp. 5328-5331
- Carreno, M.C.¹ Ruano, J.L.G.² Sanz, G.³ Toledo, M.A.⁴ Urbano, A.⁵

27
- 0001750543
- (1997) J. Org. Chem. , vol.62 , pp. 4504-4506
- Oberhauser, T.¹

28
- 0000233746
- (1955) J. Am. Chem. Soc. , vol.77 , pp. 1723-1726
- Brown, H.C.¹ Mihm, X.R.²

29
- 0006947247
- (1953) J. Chem. Soc. , pp. 1369-1372
- Brown, B.R.¹ Hammick, D.L.² Thewlis, B.H.³ Walbridge, D.J.⁴

30
- 0006910907
- Quinolines Part 1; Jones, G., Ed.; J. Wiley and Sons: New York
- (1977) , pp. 622-623
- Smalley, R.K.¹

31
- 0030602221
- (1996) Tetrahedron Lett. , vol.37 , pp. 8659-8662
- Van Arnum, S.D.¹ Ramig, K.² Stepsus, N.A.³ Dong, Y.⁴ Outten, R.A.⁵

32
- 84981841066
- (1956) Bull. Soc. Chem. Belg. , vol.65 , pp. 523-532
- Adam, J.¹ Gosselain, P.A.² Goldfinger, P.³

33
- 0006904320
- note

34
- 0006989377
- (1998) Tetrahedron Lett. , vol.39 , pp. 6165-6154
- Corey, E.J.¹ Zheng, G.Z.²

35
- 0006912337
- (1999) Chem. Pharm. Bull. , vol.38 , pp. 2446-2458
- Atsuyuki, A.¹ Ono, T.² Ohtaki, Y.³ Fukaya, C.⁴ Watanabe, M.⁵ Yokoyama, K.⁶

36
- 0006911891
- note

37
- 0006984236
- (1986) Synth. Commun. , vol.16 , pp. 441-451
- Branz, S.E.¹ Carr, J.A.²

38
- 0001847053
- (1988) Synthesis , pp. 552-553
- Majumdar, K.C.¹ Chattopadhyay, S.K.²

39
- 37049068153
- (1990) J. Chem. Soc., Perkins Trans. , pp. 2219-2223
- Majumdar, K.C.¹ Khan, A.T.² Chattopadhyay, S.K.³

40
- 85013836652
- (1979) Synthesis , pp. 177
- Willner, I.¹ Halpern, M.²

41
- 0345445145
- (1956) J. Chem. Soc. , pp. 319-323
- Bradley, W.¹ Watkinson, J.²

42
- 0006988143
- (1954) Chem. Ber. , vol.87 , pp. 1336-1339
- Arndt, F.¹ Schlatter, J.M.²

43
- 0001197262
- (1984) Tetrahedron Lett. , vol.25 , pp. 5969-5972
- Belletire, J.L.¹ Spletzer, E.G.² Pinhas, A.R.³

44
- 0000012921
- (1992) J. Org Chem. , vol.57 , pp. 1849-1855
- Crispino, G.A.¹ Breslow, R.²

45
- 0006989787
- note

46
- 0004139082
- Krieger Publishing Co.: Malabar, FL.
- (1994) Enantiomers, Racemates and Resoluations
- Jacques, J.¹ Collet, A.² Wilen, S.H.³

47
- 0006911223
- Unpublished work by Dr. Michael Maurin

48
- 0000560385
- (1995) Acc. Chem. Res. , vol.28 , pp. 193-200
- Dunitz, J.D.¹ Bernstein, J.²

49
- 0006912338
- note

50
- 0001679887
- (1977) J. Am. Chem. Soc. , vol.99 , pp. 6838-6845
- Riand, J.¹ Chenon, M.T.² Lumbroso-Bader, N.³

51
- 0003467672
- Wiley-Interscience: New York
- (1992) Advanced Organic Chemistry, 4th ed. , pp. 265
- March, J.¹

52
- 0000905636
- (1975) Tetrahedron Lett. , vol.16 , pp. 3979-3982
- Weinstock, L.M.¹ Karady, S.² Roberts, F.E.³ Hoinowski, A.M.⁴ Brenner, G.S.⁵ Lee, T.B.K.⁶ Lumma, W.C.⁷ Sletzinger, M.⁸

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.