Synthesis and antifungal activities of 5/6-arylamino-4,7-dioxobenzothiazoles

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 14, 2000, Pages 1589-1591

  Ryu, Chung Kyu ^a   Kang, Hye Young ^a   Yi, Yu Jin ^a   Shin, Keun Hwa ^a   Lee, Byung Hoon ^b  

^a Ewha Womans University   (South Korea)

^b Wonkwang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOTHIAZOLE DERIVATIVE;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS NIGER; CANDIDA ALBICANS; CANDIDA KRUSEI; CANDIDA TROPICALIS; CHEMICAL MODIFICATION; DRUG SYNTHESIS; GROWTH INHIBITION; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANTIFUNGAL AGENTS; ASPERGILLUS NIGER; CANDIDA; CANDIDA ALBICANS; CELL SURVIVAL; DRUG DESIGN; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES; TUMOR CELLS, CULTURED;

EID: 0034679651     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00301-2     Document Type: Article

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17. Unpublished data; we also tested cytotoxicities of the 4,7-dioxobenzothiazoles 3 and 4 against human tumor cell lines such as A 549 (human lung carcinoma) and Col 1 (human colon carcinoma). Among the quinones tested, the compounds 3c, 3e, 3f, 4f, 4g and 4h showed no cytotoxic activities.