Clomethiazole is neuroprotective in models of global and focal cerebral ischemia when infused at doses producing clinically relevant plasma concentrations

Brain Research

Volumn 862, Issue 1-2, 2000, Pages 59-62

  Sydserff, S G ^a   Cross, A J ^a   Murray, T K ^a   Jones, J A ^a   Green, A R ^a  

^a ASTRAZENECA   (United Kingdom)

Author keywords

Cerebral ischemia; Clomethiazole; Focal ischemia; Global ischemia; Neuroprotection

Indexed keywords

CLOMETHIAZOLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; FOREBRAIN; GERBIL; HISTOLOGY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ARTERIAL OCCLUSIVE DISEASES; CHLORMETHIAZOLE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GERBILLINAE; INFARCTION, MIDDLE CEREBRAL ARTERY; INFUSIONS, INTRAVENOUS; ISCHEMIC ATTACK, TRANSIENT; MALE; NEUROPROTECTIVE AGENTS; PROSENCEPHALON; RATS; RATS, LONG-EVANS;

EID: 0034678869     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02071-0     Document Type: Article

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