The mitogen-activated protein kinase cascade mediates neurotrophic effect of epidermal growth factor in cultured rat hippocampal neurons

Neuroscience Letters

Volumn 282, Issue 1-2, 2000, Pages 89-92

  Abe, Kazuho ^a   Saito, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Culture; Epidermal growth factor; Mitogen activated protein kinase; Neuronal survival; Rat hippocampal neurons; Tyrosine kinase

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; EPIDERMAL GROWTH FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; RECOMBINANT EPIDERMAL GROWTH FACTOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; BLOTTING, WESTERN; BUTADIENES; CELL SURVIVAL; CELLS, CULTURED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; FLAVONOIDS; HIPPOCAMPUS; MAP KINASE KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; NITRILES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TYRPHOSTINS;

EID: 0034677711     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)00867-3     Document Type: Article

References (21)

1. Abe K., Takayanagi M., Saito H. Effects of recombinant human basic fibroblast growth factor and its modified protein CS23 on survival of primary cultured neurons from various regions of fetal rat brain. Jpn. J. Pharmacol. 53:1990;221-227.
2. Abe K., Takayanagi M., Saito H. A comparison of neurotrophic effects of epidermal growth factor and basic fibroblast growth factor in primary cultured neurons from various regions of fetal rat brain. Jpn. J. Pharmacol. 54:1990;45-51.
3. Abe K., Takayanagi M., Saito H. Basic fibroblast growth factor and epidermal growth factor promote survival of primary cultured cerebellar neurons from neonatal rats. Jpn. J. Pharmacol. 56:1990;113-116.
4. 2+-dependent late phase. J. Neurochem. 67:1996;2074-2078.
5. Abe K., Saito H. Adenosine stimulates stellation of cultured rat cortical astrocytes. Brain Res. 804:1998;63-71.
6. Abe K., Saito H. The p44/42 mitogen-activated protein kinase cascade is involved in the induction and maintenance of astrocyte stellation mediated by protein kinase C. Neurosci. Res. 36:2000;251-257.
7. Carpenter G., Cohen S. Epidermal growth factor. Annu. Rev. Biochem. 48:1979;193-216.
8. Dudley D.T., Pang L., Decker S.J., Bridges A.J., Saltiel A.R. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA. 92:1995;7686-7689.
9. Fallon J.H., Seroogy K.B., Loughlin S.E., Morrison R.S., Bradshaw R.A., Knauer D.J., Cunningham D.D. Epidermal growth factor immunoreactive material in the central nervous system: location and development. Science. 224:1984;1107-1109.
10. Favata M.F., Horiuchi K.Y., Manos E.J., Daulerio A.J., Stradley D.A., Feeser W.S., Can Dyk D.E., Pitts W., Earl R.A., Hobbs F., Copeland R.A., Magolda R.L., Scherle P.A., Trzakos J.M. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273:1998;18623-18632.
11. Gomez-Pinilla F., Knauer D.J., Nieto-Sampedoro M. Epidermal growth factor immunoreactivity in rat brain: development and cellular localization. Brain Res. 438:1988;385-390.
12. Lan L., Wong N.S. Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor. FEBS Lett. 444:1999;90-96.
13. Lewis T.S., Shapiro P.S., Ahn N.G. Signal transduction through MAP kinase cascades. Adv. Cancer Res. 74:1998;49-139.
14. Morrison R.S., Kornblum H.I., Leslie F.M., Bradshaw R.A. Trophic stimulation of cultured neurons from neonatal rat brain by epidermal growth factor. Science. 238:1987;72-75.
15. Morrison R.S., Keating R.F., Moskal J.R. Basic fibroblast growth factor and epidermal growth factor exert differential trophic effects on CNS neurons. J. Neurosci. 21:1988;71-79.
16. Osherov N., Levitzki A. Epidermal-growth-factor-dependent activation of the src-family kinases. Eur. J. Biochem. 225:1994;1047-1053.
17. Seger R., Krebs E.G. The MAPK signaling cascade. FASEB J. 9:1995;726-735.
18. Sugden P.H., Clerk A. Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptors. Cell. Signal. 9:1997;337-351.
19. Thomson S., Mahadevan L.C., Clayton A.L. MAP kinase-mediated signalling to nucleosomes and immediate-early genes. Semin. Cell Dev. Biol. 10:1999;205-214.
20. Tucker M.S., Eves E.M., Wainer B.H., Rosner M.R. Activation of mitogen-activated protein kinase by epidermal growth factor in hippocampal neurons and neuronal cell lines. J. Neurochem. 61:1993;1376-1387.
21. Werner M.H., Nanney L.B., Stoscheck C.M., King L.E. Localization of immunoreactive epidermal growth factor receptor in human nervous system. J. Histochem. Cytochem. 36:1988;81-86.