Diphenyl sulfoxides as selective antagonists of the muscarinic M2 receptor

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 20, 2000, Pages 2255-2257

  Kozlowski, Joseph A ^a   Lowe, Derek B ^a   Guzik, Henry S ^a   Zhou, Guowei ^a   Ruperto, Vilma B ^a   Duffy, Ruth A ^a   McQuade, Robert ^a   Crosby Jr , Gordon ^a   Taylor, Lisa A ^a   Billard, William ^a   Binch III, Herbert ^a   Lachowicz, Jean E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 CYCLOHEXYL ALPHA [4 [(4 METHOXYPHENYL)(S) SULFINYL]PHENYL] 1 PIPERAZINEACETONITRILE; MUSCARINIC M2 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ALZHEIMER DISEASE; ARTICLE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; LEARNING; MEMORY; STRUCTURE ACTIVITY RELATION;

ACETYLCHOLINE; ADMINISTRATION, ORAL; ALKALOIDS; ANIMAL; BENZENE DERIVATIVES; CORPUS STRIATUM; DIBENZAZEPINES; DRUG DESIGN; HUMAN; MUSCARINIC ANTAGONISTS; PYRIDINES; RATS; RECEPTORS, MUSCARINIC; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034675816     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00438-8     Document Type: Article

References (18)