Selective κ-opioid antagonists related to naltrindole. Effect of side-chain spacer in the 5'-amidinoalkyl series

Bioorganic and Medicinal Chemistry Letters

Volumn 10, Issue 20, 2000, Pages 2259-2261

  Jales, Andrew R ^a   Husbands, Stephen M ^a   Lewis, John W ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

KAPPA OPIATE RECEPTOR ANTAGONIST; NALTRINDOLE;

ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION; UNITED KINGDOM;

AMIDINES; ANIMAL; BINDING, COMPETITIVE; BRAIN; CELL MEMBRANE; DRUG DESIGN; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, D-PENICILLAMINE (2,5)-; GUINEA PIGS; INDICATORS AND REAGENTS; KINETICS; NALTREXONE; NARCOTIC ANTAGONISTS; PYRROLIDINES; RECEPTORS, OPIOID, KAPPA; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0034675752     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(00)00433-9     Document Type: Article

References (10)