A novel approach in drug discovery: Synthesis of estrone - Talaromycin natural product hybrids

Chemistry - A European Journal

Volumn 6, Issue 20, 2000, Pages 3755-3760

  Tietze, Lutz F ^a   Schneider, Gyula ^b   Wölfling, János ^b   Fecher, Anja ^a   Nöbel, Thomas ^a   Petersen, Sönke ^a   Schuberth, Ingrid ^a   Wulff, Christian ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Anticancer agents; Combinatorial chemistry; Cycloadditions; Spiro compounds; Steroids; Talaromycin

Indexed keywords

ACETAL DERIVATIVE; ACETIC ACID DERIVATIVE; ANTINEOPLASTIC AGENT; ESTRONE; ESTRONE DERIVATIVE; ETHER; ETHER DERIVATIVE; HETEROCYCLIC COMPOUND; IODINE; MYCOTOXIN; NATURAL PRODUCT; REAGENT; SECOSTEROID; SPIRO COMPOUND; STEROID; TALAROMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL MEMBRANE PERMEABILITY; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIASTEREOISOMER; DRUG DESIGN; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HYBRIDIZATION; HYDROGENATION; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION REDUCTION REACTION; REDUCTION; STEREOISOMERISM; TALAROMYCIN B;

ACETALS; ANTINEOPLASTIC AGENTS; CELL MEMBRANE PERMEABILITY; DRUG DESIGN; ESTRONE; HETEROCYCLIC COMPOUNDS; HUMANS; HYDROGENATION; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; MYCOTOXINS; OXIDATION-REDUCTION; SPIRO COMPOUNDS; STEREOISOMERISM; TUMOR CELLS, CULTURED;

EID: 0034675633     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20001016)6:20<3755::AID-CHEM3755>3.0.CO;2-L     Document Type: Article

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