Degradable poly(anhydride ester) implants: Effects of localized salicylic acid release on bone

Biomaterials

Volumn 21, Issue 24, 2000, Pages 2507-2512

  Erdmann, L ^a   Macedo, B ^b   Uhrich, K E ^a  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

Author keywords

Bone formation; Bone resorption; Degradable; Poly(anhydride ester); Salicylic acid

Indexed keywords

BIODEGRADATION; BONE; ORGANIC ACIDS; POLYESTERS; POLYMERIC MEMBRANES; SWELLING;

EPITHELIAL PROLIFERATION; POLYANHYDRIDE ESTERS; SALICYLIC ACID;

IMPLANTS (SURGICAL);

POLYANHYDRIDE; POLYMER; SALICYLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABLE IMPLANT; CONTROLLED STUDY; DRUG RELEASE; FEMALE; HISTOPATHOLOGY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; PRIORITY JOURNAL;

EID: 0034672875     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(00)00118-6     Document Type: Article

References (20)

1. Erdmann L., Uhrich K. Synthesis and degradation characteristics of salicylic acid-derived poly(anhydride esters). Biomaterials. 21:2000;1941-1946.
2. Levy G. Comparative pharmacokinetics of aspirin and acetaminophen. Arch Intern Med. 141:1981;279-281.
3. Brem H., Mahaley S., Vick N., Black K., Schold S., Burger P., Friedman A., Ciric I., Eller T., Cozzens J., Kenealy J. Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas. J Neurosurg. 74:1991;441-446.
4. Brem H., Piantadosi S., Burger P., Walker M., Selker R., Vick N., Black K., Sisti M., Brem S., Mohr G., Muller P., Morawetz R., Schold S. Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas. Lancet. 345:1995;1008-1012.
5. Macedo B., Uhrich K., Erdmann L. The in vivo response to a bioactive biodegradable polymer. J Dent Res. 78:1999;459.
6. Yeh P., Berenson M., Samawitz W., Kopeckova P., Kopechek J. Site-specific drug delivery and penetration enhancement in the gastrointestinal tract. J Control Rel. 36:1995;109-124.
7. Brown J., McGarrangh G., Parkinson T., Wingard J.R., Onderdonk A. A polymeric drug for treatment of inflammatory bowel disease. J Med Chem. 26:1983;1300-1307.
8. Pattas M. Periodontal disease. In: Schuster G, editor. Oral microbiology and infectious disease. Ontario: BC Decker, 1990. p. 516-48.
9. Offenbacher S., Williams R., Jeffcoat M., Howell T., Odle B., Hall C., Johnson H., Goldhaber P. Effects of NSAIDs on beagle crevicular fluid cyclooxygenase metabolites and periodontal bone loss. J Periodontal Res. 27:1992;207-213.
10. Korman K., Blodgentt R., Brunsvold M., Holt S. Effects of topical application of meclofenamic acid and ibuprofen on bone loss, subgingival microbiota and gingival PMN response in the primate macaca fascicularis. J Periodontal Res. 25:1990;300-307.
11. Williams R. Non-steroidal anti-inflammatory drugs for altering periodontal bone loss. J Dent Res. 78:1999;638-642.
12. Rodan G. Mechanisms of action of bisphosphonate. Ann Rev Pharmacol Toxicol. 18:1998;375-388.
13. Paddock C., Youngs T., Eriksen E., Boyce R. Validation of wall thickness estimates obtained with polarized light microscopy using multiple fluorochrome levels. correlation with erosion depth estimates obtained by lamellar counting Bone. 16:1995;381-383.
14. Vane J., Botting R. Inflammation and the mechanism of action on antiinflammatory drugs. FASEB. 1:1987;89-96.
15. Jeffcoat M., Page R., Reddy M., Wannawisute A., Waite P., Palcanis K., Cogen R., Williams R., Basch C. Use of digital radiography to demonstrate the potential of naproxen as an adjunct in the treatment of rapidly progressive periodontitis. J Periodontal Res. 26:1991;415-421.
16. Roskos K.V., Fritzinger B.K., Rao S.S., Armitage G.C., Heller J. Development of a drug delivery system for the treatment of periodontal disease based on bioerodible poly(ortho esters). Biomaterials. 16:1995;313-317.
17. Kubo K., Tsukasa N., Iki K., Uehara M., Shimotsu A., Seto Y., Hyon S.-H., Ikada Y., Kubota T., Sueda T. Occlusive effects of lactic acid-glycolic acid copolymer membrane on gingival fibroblasts in vitro. J Biomed Mater Res. 39:1998;554-559.
18. Erdmann L, Campo C, Palms D, Uhrich K. Polymeric prodrugs: novel polymers with bioactive components. In: Shalaby S, McCulloch I, editors. Tailored polymeric materials for controlled delivery systems. Washington, DC: American Chemical Society Symposium Series, 1998. p. 83-91.
19. Campo C., Anastasiou T., Uhrich K. Polyanhydrides. effects of ring substitution changes on polymer properties Polym Bull. 42:1999;61-68.
20. Macedo B., Roth G., Grellner T. A tubular device for intraoral examination of rodents. Laboratory Animals. 12:1978;137-139.