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Biochimica et Biophysica Acta - General Subjects

Volumn 1524, Issue 2-3, 2000, Pages 238-246

Isolation of a high affinity scFv from a monoclonal antibody recognising the oncofoetal antigen 5T4

(8) Shaw, D M a Embleton, M J a Westwater, C a Ryan, M G b Myers, K A b Kingsman, S M b Carroll, M W b Stern, P L a

a CHRISTIE HOSPITAL (United Kingdom)

b OXFORD BIOMEDICA UK LTD (United Kingdom)

Author keywords

5T4 oncofetal antigen; Affinity; scFv; Single chain antibody; Surface plasmon resonance; Targeted therapy; Tumor

Indexed keywords

ANTIGEN 5T4; HYBRID PROTEIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5T4; ONCOFETAL ANTIGEN; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CANCER IMMUNOLOGY; CONTROLLED STUDY; DRUG ISOLATION; DRUG TARGETING; ESCHERICHIA COLI; MOUSE; NONHUMAN; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; BASE SEQUENCE; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE THERAPY; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOHISTOCHEMISTRY; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PLACENTA; RECOMBINANT FUSION PROTEINS; STOMACH NEOPLASMS; SURFACE PLASMON RESONANCE;

ANIMALIA; ESCHERICHIA COLI; EUKARYOTA; MAMMALIA; MURINAE;

EID: 0034672660 PISSN: 03044165 EISSN: None Source Type: Journal
DOI: 10.1016/S0304-4165(00)00165-3 Document Type: Article

Times cited : (28)

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