T cell responses in colorectal cancer patients: Evidence for class II HLA-restricted recognition of shared tumor-associated antigens

International Journal of Cancer

Volumn 88, Issue 6, 2000, Pages 956-961

  Bremers, Andreas J A ^a   Andreola, Salvatore ^a   Leo, Ermanno ^a   Gallino, Francesco ^a   Rini, Francesca ^a   Lombardo, Claudia ^a   Belli, Filiberto ^a   Kuppen, Peter J K ^b   Parmiani, Giorgio ^a   Castelli, Chiara ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIGEN; CARCINOEMBRYONIC ANTIGEN; HLA ANTIGEN CLASS 2; MUCIN; TUMOR ANTIGEN;

ANTIGEN PRESENTATION; ARTICLE; CANCER STAGING; CASE REPORT; CELL DIFFERENTIATION; COLORECTAL CANCER; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; LYMPHOCYTE ACTIVATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE;

ANTIGENS, NEOPLASM; COLORECTAL NEOPLASMS; DENDRITIC CELLS; EPITOPES, T-LYMPHOCYTE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; IMMUNITY, CELLULAR; T-LYMPHOCYTES;

EID: 0034672184     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0215(20001215)88:6<956::AID-IJC19>3.0.CO;2-3     Document Type: Article

References (22)

1. Induction of HLA-unrestricted and HLA-class-II-restricted cytotoxic T lymphocytes against MUC-1 from patients with colorectal carcinomas using recombinant MUC-1 vaccinia virus
2. Immunotherapy for colon cancer
3. Her-2/neu-derived peptides are tumor-associated antigens expressed by human renal cell and colon carcinoma lines and are recognized by in vitro induced specific cytotoxic T lymphocytes
4. Antigen presentation by MHC class II molecules: Invariant chain function, protein trafficking, and the molecular basis of diverse determinant capture
5. Colorectal cancer as a model for immunotherapy
6. The tea leaves of small trials
7. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing
8. The central role of CD4+ T cells in the antitumor immune response
9. Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells
10. Combined expression of HLA-DR antigen and proliferating cell nuclear antigen correlate with colorectal cancer prognosis
11. Mechanisms of antigen uptake for presentation
12. Prospective study of circulating T-lymphocyte subpopulations and disease progression in colorectal cancer
13. Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA
14. Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
15. Expression of class II major histocompatibility complex molecules correlates with human colon tumor vaccine efficacy
16. Vitiligo in patients with melanoma: Normal tissue antigens can be targets for cancer immunotherapy
17. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
18. Dendritic cell vaccines for cancer immunotherapy
19. CD4 T cells and their role in antitumor immune responses
20. Phenotypic stability of a cytotoxic T-cell line directed against an immunodominant epitope of human carcinoembryonic antigen
21. Active specific immunotherapy for stage II and stage III human colon cancer: A randomised trial
22. Human tumor antigens for cancer vaccine development