Intestinal CD8αα and CD8αβ intraepithelial lymphocytes are thymus derived and exhibit subtle differences in TCRβ repertoires

Journal of Immunology

Volumn 165, Issue 12, 2000, Pages 6716-6722

  Imhof, B A ^a   Dunon, D ^a   Courtois, D ^a   Luhtala, M ^a   Vainio, O ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

ANIMAL CELL; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; EMBRYO; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE MIGRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SMALL INTESTINE; STEM CELL; T LYMPHOCYTE; THYMOCYTE;

EID: 0034671607     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.12.6716     Document Type: Article

References (45)

1. Intestinal intraepithelial lymphocytes the plot thickens
2. Extrathymic T cell differentiation
3. Extrathymic intestinal T-cell development virtual reality?
4. Reconstitution of the extrathymical T cell compartment in the absence of irradiation
5. A novel pathway of thymus-directed T lymphocyte maturation
6. + αα intestinal intraepithelial lymphocytes early in ontogeny
7. Characteristics of fetal thymus-derived T cell receptor γδ intestinal intraepithelial lymphocytes
8. Thymus ontogeny and the development of TCR αβ intestinal intraepithelial lymphocytes
9. Identical T cell clones are located within the mouse gut epithelium and lamina propia and circulate in the thoracic duct lymph
10. Avian natural Killer cells
11. Complexity of the mouse gut T cell immune system identification of two distinct natural Killer T cell intraepithelial lineages
12. Small bowel enteropathy role of intraepithelial lymphocytes and of cytokines (IL-12, 1FN-γ, TNF) in the induction of epithelial cell death and renewal
13. Differential peripheral expansion and in vivo antigen reactivity of αβ and γδ T cells emigrating from the early lamb thymus
14. Thymic origin of embryonic intestinal γ/δ T cells
15. Migration patterns of thymus-derived γδ T cells during chicken development
16. T cell migration during development homing is not related to TCR Vβ1 repertoire selection
17. T cell migration during ontogeny and T cell repertoire generation
18. T cell receptors and T cell development
19. Evolutionary conservation of antigen recagrarian the chicken T-cell receptor β chain
20. Chicken T-cell receptor β-chain diversity an evolutionarily conserved Db-encoded glycine turn within the hypervariable CDR3 domain
21. Characterization of avian T cell receptor γ genes
22. Ontogeny of the immune system γδ and αβ T cells migrate alternatively to the periphery m alternating waves
23. A third sublineage of avian T cells can be identified with a T cell receptor-3-specific antibody
24. Avian T cells expressing γδ receptors localize in the splenic sinusoids and the intestinal epithelium
25. Ontogeny of TCR Vβ1 expression revealed novel invariant alternative transcripts
26. Evidence for a cyclic renewal of lymphocyte precursor cells m the embryonic chick thymus
27. Analysis of the first two waves of thymus homing stem cells and their T cell progeny m chick-quail chimeras
28. Analysis of chicken CD4 by monoclonal antibodies indicates evolutionary conservation between avian and mammalian species
29. Charactenzation of chicken CD8-specific monoclonal antibodies recognizing novel epitopes
30. Polymorphism of chicken CD8-α but not CD8-β
31. Charactenzation of two monoclonal antibodies against chicken T lymphocytes surface antigen
32. Characterization of chicken CD8-specific monoclonal antibodies recognizing novel epitopes
33. Monomeric homologue of mammalian CD28 is expressed on chicken T cells
34. Lymphocyte migration in viva the chicken embryo model
35. Hematopoietic commitment during embryonic stem cell differentiation in culture
36. The nucleotide sequence of the chick cytoplasmic beta-actin gene
37. Characterization and functional properties of a novel monoclonal antibody which identifies a T cell receptor in chickens
38. Ontogeny of T cell receptors in the chicken thymus
39. Avian T cell ontogeny
40. γ/δ cells
41. Major histocompatibility complex (MHC) class I recognition by natural loller cells
42. Subgroups of variable region genes of β chains of T cell receptors for antigen
43. Variability analysis of the human and mouse T cell receptor β chains
44. Selection of intraepithelial lymphocyte T cell receptors evidence for a dynamic tissue-specific process