Increasing cerebrospinal fluid chemokine concentrations despite undetectable cerebrospinal fluid HIV RNA in HIV-1-infected patients receiving antiretroviral therapy

Journal of Acquired Immune Deficiency Syndromes

Volumn 25, Issue 5, 2000, Pages 426-433

  Gisolf, Elisabeth H ^a   Van Praag, Rieneke M E ^a   Jurriaans, Suzanne ^a   Portegies, Peter ^a   Goudsmit, Jaap ^a   Danner, Sven A ^a   Lange, Joep M A ^a   Prins, Jan M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Antiretroviral therapy; CSF HIV 1 RNA; Interferon inducible protein 10; MCP 1; Soluble TNF receptor II

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; CHEMOKINE; GAMMA INTERFERON; INDINAVIR; LAMIVUDINE; MONOCYTE CHEMOTACTIC PROTEIN; NEVIRAPINE; RITONAVIR; SAQUINAVIR; STAVUDINE; TUMOR NECROSIS FACTOR RECEPTOR; VIRUS RNA; ZIDOVUDINE;

ADULT; ARTICLE; BLOOD ANALYSIS; CEREBROSPINAL FLUID EXAMINATION; CLINICAL ARTICLE; CORRELATION FUNCTION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFLAMMATION; LONG TERM CARE; MALE; PRIORITY JOURNAL; SERODIAGNOSIS; VIRUS LOAD; VIRUS REPLICATION;

EID: 0034671498     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00126334-200012150-00007     Document Type: Article

References (37)

1. 3 or less
2. Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection
3. + lymphocytes as prognostic markers of HIV-1 infection
4. Protease inhibitor-containing regimens compared with nucleoside analogues alone in the suppression of persistent HIV-1 replication in lymphoid tissue
5. Detection and quantification of HIV-1 in semen: Identification of a subpopulation of men at high potential risk of viral sexual transmission
6. Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy
7. Antiretroviral drugs and the central nervous system
8. Cerebrospinal fluid HIV-1 RNA during treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudine
9. Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavir
10. Evaluation of human immunodeficiency virus (HIV) type 1 RNA levels in cerebrospinal fluid and viral resistance to zidovudine in children with HIV encephalopathy
11. Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples
12. Measuring the "viral load" in cerebrospinal fluid in human immunodeficiency virus infection: Window into brain infection?
13. Treatment with ritonavir/saquinavir or ritonavir/saquinavir/stavudine in HIV-1 infected individuals. The effect of treatment intensification
14. Alternative multidrug regimen provides improved suppression of HIV-1 replication over triple therapy
15. Release of soluble receptors for tumor necrosis factor in clinical sepsis and experimental endotoxemia
16. Elevated cerebrospinal fluid levels of monocyte chemotactic protein-1 correlate with HIV-1 encephalitis and local virus replication
17. Cerebrospinal fluid HIV-1 RNA levels in asymptomatic patients with early stage chronic HIV-1 infection: Support for the hypothesis of local virus production
18. Cerebrospinal fluid β chemokine concentrations in neurocognitively impaired individuals infected with human immunodeficiency virus type 1
19. Time course of cerebrospinal fluid responses to antiretroviral therapy: Evidence for variable compartmentalization of infection
20. Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-gamma inducible protein-10 and monocyte chemotactic protein-1
21. Beta-chemokines and RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus associated dementia
22. Induction of monocyte chemoattractant protein-1 in HIV-1 TAT-stimulated astrocytes and elevation in AIDS dementia
23. Interleukin-8 and related chemotactic cytokines-CXC and CC chemokines
24. Chemokine expression in simian immunodeficiency virus-induced AIDS encephalitis
25. Cytokine expression in the brain during the acquired immunodeficiency syndrome
26. Increased expression of tumor necrosis factor-alpha receptors in the brains of patients with AIDS
27. Undetectable tumor necrosis factor-alpha in spinal fluid from HIV-1-infected patients
28. Soluble receptors for tumor necrosis factor as predictors of progression to AIDS in asymptomatic human immunodeficiency virus type 1 infection
29. Comparison of the amplicor HIV-1 monitor test and the nucleic sequence-based amplification assay for quantification of human immunodeficiency virus RNA in plasma, serum, and plasma subjected to freeze-thaw cycles
30. Tumor necrosis factor system levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy: Persistent TNF activation is associated with virologic and immunologic treatment failure
31. Change in circulating levels of the chemokines macrophage inflammatory proteins 1 alpha and 1 beta, RANTES monocyte chemotactic protein-1 and interleukin-16 following treatment of severely immunodeficient HIV-infected individuals with indinavir
32. Cerebrospinal fluid neopterin in human immunodeficiency virus type 1 infection
33. Markers of immune stimulation in the cerebrospinal fluid during HIV infection: A longitudinal study
34. Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: Identification by the combination of in situ polymerase chain reaction and immunohistochemistry
35. Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry
36. Human immunodeficiency virus replication induces monocyte chemoattractant protein-1 in human macrophages and U937 promonocytic cells
37. Chemokines-chemotactic cytokines that mediate inflammation