Transformation of steroids by Bacillus strains isolated from the foregut of water beetles (Coleoptera: Dytiscidae): II. Metabolism of 3β-hydroxypregn-5-en-20-one (pregnenolone)

Journal of Steroid Biochemistry and Molecular Biology

Volumn 75, Issue 2-3, 2000, Pages 187-199

  Schaaf, O ^a   Dettner, K ^a  

^a UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

Bacillus; Dytiscidae; Foregut; Gas chromatography mass spectrometry; Pregnenolone; Steroid biotransformation

Indexed keywords

PREGNENOLONE; PREGNENOLONE DERIVATIVE;

ARTICLE; BACILLUS; COLEOPTERA; CONTROLLED STUDY; DRUG ACETYLATION; HORMONE STRUCTURE; HYDROXYLATION; INTESTINE; INTESTINE FLORA; NONHUMAN; OXIDATION; STEROID METABOLISM; STEROIDOGENESIS; STRUCTURE ANALYSIS;

ANIMALS; BACILLUS; BEETLES; BIOTRANSFORMATION; DIGESTIVE SYSTEM; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HYDROXYLATION; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PREGNENOLONE;

AGABUS AFFINIS; COLEOPTERA; DYTISCIDAE;

EID: 0034671003     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-0760(00)00166-7     Document Type: Article

References (45)

1. Inhibition of sunfish feeding by defensive steroids from aquatic beetles: Structure-activity relationships
2. Identification and function of prothoracic exocrine gland steroids of the dytiscid beetles Graphoderus cinereus (L.) and Laccophilus minutus (L.)
3. Chemical defenses of freshwater organisms: Beetles and bugs
4. Insect steroid metabolism
5. Synthesis and metabolism of vertebrate-type steroids by tissues of insects: A critical evaluation
6. Stereochemistry of olefinic bond formation in defensive steroids of Acilius sulcatus (Dytiscidae)
7. Site of cholesterol absorption in some insects
8. Microbial diversity of aerobic heterotrophic bacteria inside the foregut of two tyrphophilous water beetle species
9. Transformation of steroids by Bacillus strains isolated from the foregut of water beetles (Coleoptera: Dytiscidae): I. Metabolism of androst-4-en-3,17-dione (AD)
10. Formation and gas-liquid chromatographic behavior of isometric steroid ketone methoxime derivatives
11. Effects of cytochrome P450 inhibitors and of steroid hormones on the formation of 7-hydroxylated metabolites of pregnenolone in mouse brain microsomes
12. Mass spectrometry in structural and stereochemical problems. CXXV. Mass spectrometry of some steroid trimethylsilyl ethers
13. Tabellen zur massenspektrometrischen Strukturaufklärung von Steroiden-III: Schlüsseldifferenzen von freien Steroiden
14. Determination of 17-hydroxyprogesterone in plasma by gas chromatography-mass spectrometry with high-resolution selected-ion monitoring
15. Urinary steroids from a newborn infant. Identification of 2α-hydroxy-4-pregnen-3,20-dione, 3, 15β-dihydroxy-5-pregnen-20-one and 3β, 15α-dihydroxy-5-pregnen-20-one
16. 21 steroids in faeces from germfree rats
17. Studies on the structure, biosynthesis and bacterial metabolism of 15-hydroxylated steroids in the female rat
18. Identification of 3, 17β-dihydroxyandrost-5-ene, 3β, 20α-dihydroxypregn-5-ene and epiandrosterone in human peripheral blood
19. 4- and 5α-3-ketosteroids formed during the oxidation of some 3β-hydroxysteroids by cholesterol oxidase
20. Steroids in germfree and conventional rats-4. Identification and bacterial formation of 17α-pregnane derivatives
21. 16-double bond
22. Analysis of solvolyzable steroids in human plasma by combined gas chromatography-mass spectrometry
23. Steroids in germfree and conventional rats-2. Identification of 3, 16α-dihydroxy-5α-pregnan-20-one and related compounds in faeces from germfree rats
24. 21 steroids in faeces from infants
25. + ion in the mass spectra of trimethylsilyl ethers of dehydroepiandrosterone and related compounds
26. The use of steroid profiling in the resolution of pregnenolone metabolites from porcine testicular preparations
27. Newer approaches to the isolation, identification, and quantitation of steroids in biological materials
28. Mass spectra of some highly substituted pregnanes and pregnenes
29. Microbiological reactions with steroids
30. Steroid transformations by microorganisms
31. Steroid transformations by microorganisms - II
32. Steroid transformations by microorganisms - III
33. Current trends in microbial steroid biotransformation
34. meg
35. meg, the steroid-15β-monooxygenase from Bacillus megaterium
36. Thermostable cytochrome P450 steroid hydroxylase from a thermophilic Bacillus strain
37. Hydroxylation of deoxycorticosterone by Bacillus cereus, strain T
38. Metabolism of progesterone and testosterone by a Bacillus sp.
39. Metabolism of 17-hydroxyprogesterone by a Bacillus species
40. Metabolism of 11-deoxycortisol by a Bacillus species
41. Metabolism of progesterone by a Bacillus species