The acidic pin of RuvA modulates holliday junction binding and processing by the RuvABC resolvasome

EMBO Journal

Volumn 19, Issue 22, 2000, Pages 6266-6274

  Ingleston, S M ^a   Sharples, G J ^a   Lloyd, R G ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Branch migration; Escherichia coli; Helicase; Recombination; Resolution

Indexed keywords

DNA; DNA BINDING PROTEIN; DOUBLE STRANDED DNA; HELICASE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; DNA REPAIR; ESCHERICHIA COLI; GENETIC RECOMBINATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN STRUCTURE;

ESCHERICHIA COLI;

EID: 0034669196     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.22.6266     Document Type: Article

References (36)

1. Crystal structure of the Holliday junction DNA in complex with a single RuvA tetramer
2. Nucleotide sequencing of the ruv region of Escherichia coli K-12 reveals a LexA regulated operon encoding two genes
3. Identification of three aspartic acid residues essential for catalysis by the RusA Holliday junction resolvase
4. Sequence-specificity and biochemical characterization of the RusA Holliday junction resolvase of Escherichia coli
5. Recognition and manipulation of branched DNA by the RusA Holliday junction resolvase of Escherichia coli
6. Formation of RuvABC-Holliday junction complexes in vitro
7. In vitro reconstitution of the late steps of genetic recombination in E.coli
8. Crystal structure of E.coli RuvA with bound DNA Holliday junction at 6 Å resolution
9. Branch migration during homologous recombination: Assembly of a RuvAB-Holliday junction complex in vitro
10. Initiation of genetic recombination and recombination-dependent replication
11. Conjugational recombination in resolvase-deficient ruvC mutants of Escherichia coli K-12 depends on recG
12. Homologous recombination
13. Dissociation of synthetic Holliday junctions by E.coli RecG protein
14. Effect of ruv mutations on recombination and DNA repair in Escherichia coli K12
15. Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82
16. Resolution of Holliday intermediates in recombination and DNA repair: Indirect suppression of ruvA, ruvB and ruvC mutations
17. Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progression
18. Replication fork arrest and DNA recombination
19. Interaction of E.coli RuvA and RuvB proteins with synthetic Holliday junctions
20. Crystal structure of the DNA recombination protein RuvA and a model for its binding to the Holliday junction
21. Structural similarities between E.coli RuvA protein and other DNA binding proteins and a mutational analysis of its binding to the Holliday junction
22. Crystal structure of an octameric RuvA-Holliday junction complex
23. RuvAB acts at arrested replication forks
24. Processing of intermediates in recombination and DNA repair: Identification of a new endonuclease that specifically cleaves Holliday junctions
25. Holliday junction processing in bacteria: Insights from the evolutionary conservation of RuvABC
26. Structure and regulation of the Escherichia coli ruv operon involved in DNA repair and recombination
27. Damage to DNA induces expression of the ruv gene of Escherichia coli
28. Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides
29. Purification and physical properties of the RuvA and RuvB proteins of Escherichia coli
30. Functional interactions between the Holliday junction resolvase and the branch migration motor of Escherichia coli
31. Assembly of the Escherichia coli RuvABC resolvasome directs the orientation of Holliday junction resolution
32. Processing of recombination intermediates by the RuvABC proteins
33. Reverse branch migration of Holliday junctions by RecG protein: A new mechanism for resolution of intermediates in recombination and DNA repair
34. Interactions between RuvA and RuvC at Holliday junctions: Inhibition of junction cleavage and formation of a RuvA-RuvC-DNA complex
35. Effect of DNA topology on Holliday junction resolution by Escherichia coli RuvC and bacteriophage T7 endonuclease I
36. Coordinated actions of RuvABC in Holliday junction processing