Neither the A- nor B-repeat regions of the fibrinogen-binding protein of Streptococcus equi subsp. equi are essential for fibrinogen binding

FEMS Microbiology Letters

Volumn 190, Issue 2, 2000, Pages 317-321

  Meehan, Mary ^a,b   Muldowney, Deirdre A ^a   O'Meara, Fergal ^a   Owen, Peter ^a  

^a Moyne Institute of Preventive Medicine   (Ireland)

^b BioResearch Ireland Trinity C   (Ireland)

Author keywords

Fibrinogen binding protein; Ligand binding domain; Repeat sequence; Streptococcus equi subsp. equi

Indexed keywords

BACTERIAL PROTEIN; FIBRINOGEN; FIBRINOGEN BINDING PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; STREPTOCOCCUS EQUI;

ANIMALS; BACTERIAL PROTEINS; CARRIER PROTEINS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FIBRINOGEN; IMMUNOBLOTTING; LIGANDS; RECOMBINANT PROTEINS; REPETITIVE SEQUENCES, NUCLEIC ACID; STREPTOCOCCUS EQUI;

BACTERIA (MICROORGANISMS); EQUUS CABALLUS; POSIBACTERIA; STREPTOCOCCUS; STREPTOCOCCUS EQUI SUBSP. EQUI;

EID: 0034666614     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(00)00355-4     Document Type: Article

References (24)

1. Timoney J.F. Strangles. Vet. Clin. North Am. Equine Pract. 9:1993;365-374.
2. Meehan M., Nowlan P., Owen P. Affinity purification and characterization of a fibrinogen-binding protein complex which protects mice against lethal challenge with Streptococcus equi subsp. equi. Microbiology. 144:1998;993-1003.
3. Timoney J.F., Artiushin S.C., Boschwitz J.S. Comparison of the sequences and functions of Streptococcus equi M-like proteins SeM and SzPSe. Infect. Immun. 65:1997;3600-3605.
4. Boschwitz J.S., Timoney J.F. Characterization of the antiphagocytic activity of equine fibrinogen for Streptococcus equi subsp. equi. Microb. Pathog. 17:1994;121-129.
5. Boschwitz J.S., Timoney J.F. Inhibition of C3 deposition on Streptococcus equi subsp. equi by M protein a mechanism for survival in equine blood. Infect. Immun. 62:1994;3515-3520.
6. Meehan M., Muldowney D.A., Watkins N.J., Owen P. Localization and characterization of the ligand-binding domain of the fibrinogen-binding protein (FgBP) of Streptococcus equi subsp. equi. Microbiology. 146:2000;1187-1194.
7. Navarre W.W., Schneewind O. Surface proteins of Gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol. Mol. Biol. Rev. 63:1999;174-229.
8. Lech, K. and Brent, R. (1997) Media preparation and bacteriological tools. In: Current Protocols in Molecular Biology (Ausubel, F.M. et al., Eds.), pp. 1.1.1-1.1.6. Wiley and Sons, New York.
9. Yu C.-E., Ferretti J.J. Molecular epidemiologic analysis of the type A streptococcal exotoxin (erythrogenic toxin) gene (speA) in clinical Streptococcus pyogenes strains. Infect. Immun. 57:1989;3715-3719.
10. Feliciello I., Chinali G. A modified alkaline lysis method for the preparation of highly purified plasmid DNA from Escherichia coli. Anal. Biochem. 212:1993;394-401.
11. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
12. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
13. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding. Anal. Biochem. 72:1976;248-254.
14. Lupas A. Prediction and analysis of coiled-coil structures. Methods Enzymol. 266:1996;513-525.
15. Lupas A., Van Dyke M., Stock J. Predicting coiled coils from protein sequences. Science. 252:1991;1162-1164.
16. Åkesson P., Schmidt K.-H., Cooney J., Bjorck L. M1 protein and protein H: IgGFc- and albumin-binding streptococcal surface proteins encoded by adjacent genes. Biochem. J. 300:1994;877-886.
17. Reichardt W., Gubbe K., Schmidt K.H. M3-protein with close sequence homology to M12 protein binds fibrinogen, albumin, fibronectin, but not to any subclass of IgG - localization of binding regions. Dev. Biol. Stand. 85:1995;179-182.
18. Reichardt, W., Schmidt, K.-H., Amberg, C. and Gubbe, K. (1997) Mapping of binding sites for human serum albumin and fibrinogen on the M3-protein. Molecular model and function in the pathogenic mechanism. In: Streptococci and the Host (Horaud, T., Bouvet, A., Leclercq, R., de Montclos, H. and Sicard, M., Eds.), pp. 577-579. Plenum Press, New York.
19. Talay S.R., Grammel M.P., Chhatwal G.S. Structure of a group C streptococcal protein that binds to fibrinogen, albumin and immunoglobulin G via overlapping modules. Biochem. J. 315:1996;577-582.
20. Kehoe, M.A. (1994) Cell-wall-associated proteins in Gram-positive bacteria. In: Bacterial Cell Wall, New Comprehensive Biochemistry, Vol. 27 (Ghuysen, J.-M. and Hakenbeck, R., Eds.), pp. 217-261. Elsevier, Amsterdam.
21. Vasi J., Frykberg L., Carlsson L.E., Lindberg M., Guss B. M-like proteins of Streptococcus dysgalactiae. Infect. Immun. 68:2000;294-302.
22. O'Shea E.K., Klemm J.D., Kim P.S., Alber T. X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil. Science. 254:1991;539-544.
23. Harbury P.B., Zhang T., Kim P.S., Alber T. A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants. Science. 262:1993;1401-1407.
24. Cohen C., Parry D.A.D. α-Helical coiled coils: more facts and better predictions. Science. 263:1994;488-489.