High-performance liquid chromatographic method for the simultaneous determination of nalbuphine and its prodrug, sebacoyl dinalbuphine ester, in dog plasma and application to pharmacokinetic studies in dogs

Journal of Chromatography B: Biomedical Sciences and Applications

Volumn 746, Issue 2, 2000, Pages 241-247

  Pao, Li Heng ^a   Hsiong, Cheng Huei ^a   Hu, Oliver Yoa Pu ^a   Ho, Shung Tai ^a  

^a NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Nalbuphine; Sebacoyl dinalbuphine ester

Indexed keywords

NALBUPHINE; PRODRUG; SEBACOYL DINALBUPHINE ESTER; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CALIBRATION; CONTROLLED STUDY; DOG; DRUG DETERMINATION; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

ANALGESICS; ANIMALS; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; NALBUPHINE; PRODRUGS; REPRODUCIBILITY OF RESULTS;

EID: 0034666474     PISSN: 13872273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4347(00)00326-1     Document Type: Article

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