Evidence for a Menkes-like protein with a nuclear targeting sequence

Biochemical Journal

Volumn 350, Issue 3, 2000, Pages 855-863

  Reddy, M C M ^a   Majumdar, S ^a   Harris, E D ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Alternative splicing; ATP7A mRNA; Copper transport; Menkes disease gene; Nuclear localization sequence

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (COPPER); CELL EXTRACT; COMPLEMENTARY DNA; COPPER; GREEN FLUORESCENT PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; PROTEIN NML 45; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; CYTOSOL; DNA SEQUENCE; FIBROBLAST; GENE INSERTION; HUMAN; HUMAN CELL; MENKES SYNDROME; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; TRANSLATION INITIATION;

ADENOSINETRIPHOSPHATASE; ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMAL; BASE SEQUENCE; CARRIER PROTEINS; CHO CELLS; DNA, COMPLEMENTARY; HAMSTERS; HUMAN; MOLECULAR SEQUENCE DATA; NUCLEAR LOCALIZATION SIGNAL; NUCLEAR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPPORT, U.S. GOV'T, NON-P.H.S.; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR CELLS, CULTURED;

EID: 0034664938     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3500855     Document Type: Article

References (24)

1. Cellular copper transport
2. Molecular structure of the Menkes disease gene (ATP7A)
3. Characterization of the exon structure of the Menkes disease gene using vectorette PCR
4. Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice
5. Multiple transcripts coding for the Menkes gene: Evidence for alternative splicing of Menkes mRNA
6. Multiple forms of the Menkes Cu-ATPAse
7. Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase
8. PSORT: A program tot detecting sorting signals in proteins and predicting their cellular localization
9. Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase
10. Isolation of a candidate gene for Menkes disease that encodes a potential heavy metal binding protein
11. Coincident expression of Menkes gene with copper efflux in human placental cells
12. Constitutive skipping of alternatively spliced exon 10 in the ATP7A gene abolishes Golgi localization of the Menkes protein and produces the occipital horn syndrome
13. A Golgi localization signal identified in the Menkes recombinant protein
14. Ovalbumin gene: Evidence for a leader sequence in mRNA and DNA sequences at the intron-exon boundaries
15. Multiple steps in the regulation of transcription factor revel and activity
16. Significant increase of a specific variant TSG101 transcript during the progression of cervical neoplasia
17. Multiple truncated transcripts of TSG101 in gastrointestinal cancers
18. Expression of a new isoform of the tumor susceptibility TSGI01 protein lacking a leucine zipper domain in Burkitt lymphoma cell lines
19. Differential regulation of glucocorticoid receptor transcriptional activation via AF-1-associated proteins
20. Tumor susceptibility gene 101 protein represses androgen receptor transactivation and interacts with p300
21. Ran and nuclear transport
22. Structure-function analysis of the protein-binding domains of Mac1p, a copper-dependent transcriptional activator of copper uptake in Saccharomyces cerevisiae
23. Copy is a copper-inducible repressor of the Enterococcus hirae copper ATPases