Ca2+/calmodulin-dependent facilitation and inactivation of P/Q-type Ca2+ channels

Journal of Neuroscience

Volumn 20, Issue 18, 2000, Pages 6830-6838

  Lee, Amy ^a   Scheuer, Todd ^a   Catterall, William A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Action potential; Calcium channel; Calmodulin; Facilitation; Inactivation; Synaptic plasticity

Indexed keywords

BARIUM ION; CALCIUM CHANNEL; CALCIUM ION; CALMODULIN; CALMODULIN INHIBITOR; CHELATING AGENT; COMPLEMENTARY DNA; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL)ETHER N,N,N',N' TETRAACETIC ACID; GUANINE NUCLEOTIDE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); ION CHANNEL; UNCLASSIFIED DRUG; 1,2-BIS(2-AMINOPHENOXY)ETHANE-N,N,N',N'-TETRAACETIC ACID; BARIUM; CALCIUM; CALCIUM CHANNEL N TYPE; DRUG DERIVATIVE; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GUANOSINE 5' O (2 THIODIPHOSPHATE); GUANOSINE 5'-O-(2-THIODIPHOSPHATE); GUANOSINE DIPHOSPHATE; NUCLEOTIDE; VOLTAGE DEPENDENT CALCIUM CHANNEL (P Q TYPE); VOLTAGE-DEPENDENT CALCIUM CHANNEL (P-Q TYPE);

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; BINDING SITE; GENE EXPRESSION; MOLECULAR CLONING; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION; CELL LINE; DRUG EFFECT; ELECTROSTIMULATION; GENETIC TRANSFECTION; GENETICS; HUMAN; INTRACELLULAR FLUID; METABOLISM;

ACTION POTENTIALS; BARIUM; CALCIUM; CALCIUM CHANNELS, N-TYPE; CALMODULIN; CELL LINE; CHELATING AGENTS; EGTAZIC ACID; ELECTRIC STIMULATION; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; HUMANS; INTRACELLULAR FLUID; THIONUCLEOTIDES; TRANSFECTION;

EID: 0034664238     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-18-06830.2000     Document Type: Article

References (34)

1. Facilitation of presynaptic calcium currents in the rat brainstem
2. Depletion of calcium in the synaptic cleft of a calyx-type synapsein the rat brainstem
3. Splicihg of α(1A) subunit gene generates phenotypic variants of P- and Q-type calcium channels
4. 2+ channels in nerve terminals of the neurohypophysis
5. Relief of G-protein inhibition of calcium channels and short-term synaptic facilitation in cultured hippocampal neurons
6. 2+ channels in HEK 293 cells
7. Facilitation of the presynaptic calcium current at an auditory synapse in rat brainstem
8. 2+ channels
9. 2+ channel expressed in Xenopus oocytes
10. Co-operative action of calcium ions in transmitter release at the neuromuscular junction
11. 2+ current in excitable cells
12. 2+ channels in mammalian central neurons
13. Inactivation of presynaptic calcium current contributes to synaptic depression at a fast central synapse
14. 2+ channels by G protein βγ subunits
15. Voltage-dependent modulation of N-type calcium channels by G-protein βγ subunits
16. Calmodulin-binding domains: Just two faced or multi-faceted?
17. 2+-activated potassium channels
18. Mutations in paramecium calmodulin indicate functional differences between the C-terminal and N-terminal lobes in vivo
19. 2+/calmodulin binds to and modulates P/Q-type calcium channels
20. P-type calcium channels in rat central and peripheral neurons
21. Calcium control of transmitter release at a cerebellar synapse
22. Preferential closed-state inactivation of neuronal calcium channels
23. 2+-dependent inactivation of L-type calcium channels
24. The localization and functional properties of a rat brain α(1A) calcium channel reflect similarities to neuronal Q- and P-type channels
25. Determinants of PKC-dependent modulation of a family of neuronal calcium channels
26. 1- and β-subunits in developing and mature rat brain
27. A quantitative analysis of presynaptic calcium dynamics that contribute to short-term enhancement
28. P-type calcium channels in the somata and dendrites of adult cerebellar Purkinje cells
29. 2+ binding to calmodulin
30. High-frequency firing helps replenish the readily releasable pool of synaptic vesicles
31. Immunochemical identification and subcellular distribution of the α1A subunits of brain calcium channels
32. The reduced release probability of releasable vesicles during recovery from short-term synaptic depression
33. Modification of the calcium and calmodulin sensitivity of the type I adenylyl cyclase by mutagenesis of its calmodulin binding domain
34. Calcium- and activity-dependent synaptic plasticity