The duplication of an eight-residue helical stretch in Staphylococcal nuclease is not helical: A model for evolutionary change

Proteins: Structure, Function and Genetics

Volumn 40, Issue 3, 2000, Pages 465-472

  Nguyen, Duc M ^a   Gittis, Apostolos G ^a   Lattman, Eaton E ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Circular dichroism; Duplication; Helical propensity; Staphylococcal nuclease; X ray crystallography

Indexed keywords

MUTANT PROTEIN; NUCLEASE; TRIFLUOROETHANOL;

ALPHA HELIX; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; GENE DUPLICATION; MOLECULAR EVOLUTION; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; STAPHYLOCOCCUS; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; CIRCULAR DICHROISM; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; EVOLUTION, MOLECULAR; GENE DUPLICATION; MICROCOCCAL NUCLEASE; MODELS, MOLECULAR; MUTATION; OLIGOPEPTIDES; PROTEIN STRUCTURE, SECONDARY; REPETITIVE SEQUENCES, AMINO ACID; SUPPORT, NON-U.S. GOV'T;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS;

EID: 0034663622     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0134(20000815)40:3<465::AID-PROT130>3.0.CO;2-A     Document Type: Article

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