Effects of modification of the hydrophobic C-1-C-16 segment of tautomycin on its affinity to type-1 and type-2A protein phosphatases

Biochemical Journal

Volumn 350, Issue 1, 2000, Pages 81-88

  Takai, A ^a   Tsuboi, K ^a   Koyasu, M ^a   Isobe, M ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Enantiomer; Enzyme inhibitor; Okadaic acid; Structure affinity relationship

Indexed keywords

OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; TAUTOMYCIN;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; DISSOCIATION CONSTANT; DRUG PROTEIN BINDING; ENANTIOMER; ENZYME SUBUNIT; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANTIBIOTICS, ANTIFUNGAL; PHOSPHOPROTEIN PHOSPHATASE; PYRANS; SPIRO COMPOUNDS; SUBSTRATE SPECIFICITY;

EID: 0034663558     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3500081     Document Type: Article

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