Dose range evaluation of a new inactivated hepatitis A vaccine administered as a single dose followed by a booster

Vaccine

Volumn 19, Issue 1, 2000, Pages 10-15

  Minutello, M ^a   Zotti, C ^c   Orecchia, S ^c   Di Martino, E ^a   Bastianoni, I ^a   Ypma, E ^b   Ruggenini Moiraghi, A ^c   Podda, A ^a  

^a CHIRON VACCINES   (Italy)

^b Chiron Biostatist Clin Data Mgmt   (Netherlands)

^c NONE

Author keywords

Hepatitis A; Immunisation; Single dose schedule

Indexed keywords

HEPATITIS A VACCINE;

ADULT; ANTIBODY RESPONSE; ANTIGENICITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; ENZYME LINKED IMMUNOSORBENT ASSAY; HEPATITIS A; HUMAN; HUMAN EXPERIMENT; IMMUNIZATION; IMMUNOGENICITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEROCONVERSION; SINGLE BLIND PROCEDURE;

ADOLESCENT; ADULT; DEMOGRAPHY; DOUBLE-BLIND METHOD; FEMALE; HEPATITIS A ANTIBODIES; HEPATITIS A VACCINES; HEPATITIS ANTIBODIES; HUMANS; IMMUNITY; IMMUNIZATION, SECONDARY; MALE; VACCINES, INACTIVATED; VIRAL HEPATITIS VACCINES;

EID: 0034663540     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(00)00156-0     Document Type: Article

References (17)

1. Lemon S.M. Type A viral hepatitis: new developments in an old disease. New Engl. J. Med. 313:1985;1059-1067.
2. Hadler S.C. Global impact of hepatitis A virus infection: changing patterns. Hollinger F.B., Lemon S.M., Margolis H.S. Viral hepatitis and liver disease. 1991;14-20 Williams & Wilkins, Baltimore, MD.
3. Gust I.D., Lehmann N.I., Lucas C.R. Relationship between prevalence of antibody to hepatitis A antigen and age: a cohort effect? J. Inf. Dis. 138:1978;425-426.
4. Forbes A., Williams R. Changing epidemiology and clinical aspects of hepatitis A. Br. Med. Bull. 46:1990;303-318.
5. Feinstone S.M. Hepatitis A. Prog. Liver Dis. 8:1986;299-310.
6. Centers for Disease Control. Hepatitis A among drug abusers. MMWR. 37:1988;297-301.
7. Margolis H.S., Hadler S.C., Shapiro C.N., et al. Immunization strategies for the control of hepatitis A in the United States. Hollinger F.B., Lemon S.M., Margolis H.S. Viral hepatitis and liver disease. 1991;724-726 Williams & Wilkins, Baltimore, MD.
8. Kluge T. Gamma-globulin in the prevention of viral hepatitis. Acta Med. Scand. 174:1963;460-477.
9. Winokur P.L., Stapleton J.T. Immunoglobulin prophylaxis for hepatitis A. Clin. Infect. Dis. 14:1992;580-586.
10. Pellegrini V., Fineschi N., et al. Preparation and immunogenicity of an inactivated hepatitis A vaccine. Vaccine. 11:(3):1993;383-387.
11. Theilmann L., Kallinowsky B., Gmelin K., Hofmann F., Scheiermann N., Wohland B., Stickl H., Maiwald H., Moriabadi F.K., Bock H.L., Clemens R., Safary A., André F.E. Reactogenicity and immunogenicity of three different lots of a hepatitis A vaccine. Vaccine. 10:(Suppl 1):1992;S132-134.
12. Binn L.N., MacArthy P.O., Marchwicki R.H., Sjogren M.H., Hoke C.H. Jr, Burge J.R., D'Hondt E. Laboratory tests and reference reagents employed in studies of inactivated hepatitis A vaccine. Vaccine. 10:(Suppl 1):1992;S102-105.
13. Victor J., Knudsen Dahl J., Nielsen L.P., Fomsgaard A., Thybo S., Bygbjerg I., Westh H. Hepatitis A vaccine. A new convenient single-dose schedule with booster when long-term immunization is warranted. Vaccine. 12:1994;1327-1329.
14. Shouval D., Ashur Y., Adler R., Lewis J.A., Miller W., Kuter B., Brown L., Nalin D.R. Safety, tolerability and immunogenicity of an inactivated hepatitis A vaccine: effects of single and booster injections, and comparison to administration of immune globulin. J. Hepatol. 18:(Suppl 2):1993;32-37.
15. Ashur Y., Adler R., Rowe M., Shouval D. Comparison of immunogenicity of two hepatitis A vaccines - VAQTA and HAVRIX - in young adults. Vaccine. 17:1999;2290-2296.
16. Sagliocca L., Amoroso P., Stroffolini T., Adamo B., Tosti M.E., Lettieri G., Esposito C., Buonocore S., Pierri P., Mele A. Efficacy of hepatitis A vaccine in prevention of secondary hepatitis A infection: a randomised trial. Lancet. 353:1999;1136-1139.
17. Weekly Epidemiological Record, Hepatitis A vaccines. No. 5 4 February 2000:38-44.