Platelet adhesion to collagen in healthy volunteers is influenced by variation of both α2β1 density and von Willebrand factor

Blood

Volumn 96, Issue 4, 2000, Pages 1433-1437

  Roest, M ^a   Sixma, J J ^a   Wu, Y P ^a   Ijsseldijk, M J W ^a   Tempelman, M ^a   Slootweg, P J ^a   De Groot, P G ^a   Van Zanten, G H ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 4; INTEGRIN; MAGNESIUM; VON WILLEBRAND FACTOR;

ARTICLE; BLEEDING TIME; CELL SURFACE; DENSITY; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN PROTEIN INTERACTION; THROMBOCYTE ADHESION;

EID: 0034663181     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v96.4.1433.h8001433_1433_1437     Document Type: Article

References (23)

1. Platelet adhesion to collagen: An update
2. Role of factor VIII-von Willebrand factor and fibronectin in the interaction of platelets in flowing blood with monomeric and fibrillar human collagen types I and III
3. Platelet adhesion to multimeric and dimeric von Willebrand factor and to collagen type III preincubated with von Willebrand factor
4. Simple collagen-like peptides support platelet adhesion under static but not under flow conditions: Interaction via alpha2 beta1 and von Willebrand factor with specific sequences in native collagen is a requirement to resist shear forces
5. Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow
6. Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin)
7. Human blood platelets showing no response to collagen fail to express surface glycoprotein 1a
8. Variability of integrin alpha 2 beta 1 activity on human platelets
9. Hereditary variation in platelet integrin alpha 2 beta 1 density is associated with two silent polymorphisms in the alpha 2 gene coding sequence
10. Low platelet alpha2beta1 levels in type I von Willebrand disease correlate with impaired platelet function in a high shear stress system
11. Factor VIII, ABO blood group and the incidence of ischaemic heart disease
12. Nucleotide polymorphisms in the alpha2 gene define multiple alleles that are associated with differences in platelet alpha2 beta1 density
13. Fibronectin in artery sub-endothelium is important for platelet adhesion
14. Collagen-platelet interactions: Evidence for a direct interaction of collagen with platelet GPIa/IIa and an indirect interaction with platelet GPIIb/IIIa mediated by adhesive proteins
15. A murine monoclonal antibody that identifies the 157/130 kDa platelet collagen receptor
16. Measurement of the bleeding time
17. Platelet adhesion to collagen type IV under flow conditions
18. Platelet adhesion to vascular cells: The role of exogenous yon Willebrand factor in platelet adhesion
19. Comparison of platelet membrane markers for the detection of platelet activation in vitro and during platelet storage and cardlopulmonary bypass surgery
20. Factor V Arg506GIn mutation is not associated with cardiovascular mortality in older women
21. ATP-ADP compartmentation in storage pool deficient platelets: Correlation between granule-bound ADP and the bleeding time
22. Association of the platelet glycoprotein Ia C807T gene polymorphism with non-fatal myocardial infarction in younger patients
23. Association of two silent polymorphisms of platelet glycoprotein Ia/IIa receptor with risk of myocardial infarction: A case-control study