-
1
-
-
0030046797
-
Identification of scavenger receptor SR-BI as a high density lipoprotein receptor
-
Acton S, Rigotti A, Landschulz KT, Xu S, Hobbs HH, Krieger M. 1996. Identification of scavenger receptor SR-BI as a high density lipoprotein receptor. Science 271:518-520.
-
(1996)
Science
, vol.271
, pp. 518-520
-
-
Acton, S.1
Rigotti, A.2
Landschulz, K.T.3
Xu, S.4
Hobbs, H.H.5
Krieger, M.6
-
2
-
-
0030867936
-
Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease
-
Aleshkov S, Abraham CR, Zannis VI. 1997. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease. Biochemistry 36:10571-10580.
-
(1997)
Biochemistry
, vol.36
, pp. 10571-10580
-
-
Aleshkov, S.1
Abraham, C.R.2
Zannis, V.I.3
-
3
-
-
0030038809
-
Scavenging of Alzheimer's amyloid β-protein by microglia in culture
-
Ard MD, Cole GM, Wei J, Mehrle AP, Fratkin JD. 1996. Scavenging of Alzheimer's amyloid β-protein by microglia in culture. J Neurosci Res 43:190-202.
-
(1996)
J Neurosci Res
, vol.43
, pp. 190-202
-
-
Ard, M.D.1
Cole, G.M.2
Wei, J.3
Mehrle, A.P.4
Fratkin, J.D.5
-
4
-
-
0031278270
-
Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition
-
Bales KR, Verina T, Ghetti B, Dodel RC, Du Y, Altstie L, Bender M, Hyslop P, Johnstone EM, Little SP, Cummins DJ, Piccardo P, Paul SM. 1997. Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition. Nature Genet 17: 263-264.
-
(1997)
Nature Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Ghetti, B.3
Dodel, R.C.4
Du, Y.5
Altstie, L.6
Bender, M.7
Hyslop, P.8
Johnstone, E.M.9
Little, S.P.10
Cummins, D.J.11
Piccardo, P.12
Paul, S.M.13
-
5
-
-
0031882562
-
β-Amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons
-
Beffert U, Aumont N, Dea D, Lussier-Cacan S, Davignon J, Poirier J. 1998. β-Amyloid peptides increase the binding and internalization of apolipoprotein E to hippocampal neurons. J Neurochem 70:1458-1466.
-
(1998)
J Neurochem
, vol.70
, pp. 1458-1466
-
-
Beffert, U.1
Aumont, N.2
Dea, D.3
Lussier-Cacan, S.4
Davignon, J.5
Poirier, J.6
-
6
-
-
0028019733
-
Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS
-
Bell MD, Lopez-Gonzalez R, Lawson L, Hughes D, Fraser I, Gordon S, Perry VH. 1994. Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS. J Neurocytol 23:605-613.
-
(1994)
J Neurocytol
, vol.23
, pp. 605-613
-
-
Bell, M.D.1
Lopez-Gonzalez, R.2
Lawson, L.3
Hughes, D.4
Fraser, I.5
Gordon, S.6
Perry, V.H.7
-
7
-
-
16944364644
-
Amyloid β-peptide is transported on lipoproteins and albumin in human plasma
-
Biere AL, Ostaszewski B, Stimson ER, Hyman BT, Maggio JE, Selkoe DJ. 1996. Amyloid β-peptide is transported on lipoproteins and albumin in human plasma. J Biol Chem 271:32916-32922.
-
(1996)
J Biol Chem
, vol.271
, pp. 32916-32922
-
-
Biere, A.L.1
Ostaszewski, B.2
Stimson, E.R.3
Hyman, B.T.4
Maggio, J.E.5
Selkoe, D.J.6
-
8
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz S, Klein WL. 1996. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271:4436-4440.
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
9
-
-
0028972292
-
Specificity in recognition of amyloid-β peptide by the serpin-enzyme complex receptor in hepatoma cells and neuronal cells
-
Boland K, Manias K, Perlmutter DH. 1995. Specificity in recognition of amyloid-β peptide by the serpin-enzyme complex receptor in hepatoma cells and neuronal cells. J Biol Chem 47:28022-28028.
-
(1995)
J Biol Chem
, vol.47
, pp. 28022-28028
-
-
Boland, K.1
Manias, K.2
Perlmutter, D.H.3
-
10
-
-
0028912790
-
Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid
-
Borghini I, Barja F, Pometta D, James RW. 1995. Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid. Biochim Biophys Acta 1255:192-200.
-
(1995)
Biochim Biophys Acta
, vol.1255
, pp. 192-200
-
-
Borghini, I.1
Barja, F.2
Pometta, D.3
James, R.W.4
-
11
-
-
85165121214
-
Increased levels of apolipoprotein E4 accelerate amyloid deposition in APPsw transgenic mouse brain
-
Carter DB, Dunn E, Mckinley DD, Boyle TP, Kuiper SL, Weaver RJ, Vidmar TJ, Boller JA, Lennon DJ, Stratman NC, Gurney ME. 1999. Increased levels of apolipoprotein E4 accelerate amyloid deposition in APPsw transgenic mouse brain. Soc Neurosci Abstr 25: 1348.
-
(1999)
Soc Neurosci Abstr
, vol.25
, pp. 1348
-
-
Carter, D.B.1
Dunn, E.2
Mckinley, D.D.3
Boyle, T.P.4
Kuiper, S.L.5
Weaver, R.J.6
Vidmar, T.J.7
Boller, J.A.8
Lennon, D.J.9
Stratman, N.C.10
Gurney, M.E.11
-
12
-
-
0029151238
-
Apolipoprotein E carboxyl-terminal fragments are complexed to amyloids A and L
-
Castano EM, Prelli F, Pras M, Frangione B. 1995a. Apolipoprotein E carboxyl-terminal fragments are complexed to amyloids A and L. J Biol Chem 270: 17610-17615.
-
(1995)
J Biol Chem
, vol.270
, pp. 17610-17615
-
-
Castano, E.M.1
Prelli, F.2
Pras, M.3
Frangione, B.4
-
13
-
-
0028986408
-
Fibrillogenesis in Alzheimer's disease of amyloid β peptides and apolipoprotein E
-
Castano EM, Prelli F, Wisniewski T, Golabek A, Kumar RA, Soto C, Frangione B. 1995b. Fibrillogenesis in Alzheimer's disease of amyloid β peptides and apolipoprotein E. Biochem J 306: 599-604.
-
(1995)
Biochem J
, vol.306
, pp. 599-604
-
-
Castano, E.M.1
Prelli, F.2
Wisniewski, T.3
Golabek, A.4
Kumar, R.A.5
Soto, C.6
Frangione, B.7
-
14
-
-
0029905421
-
Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide A beta
-
Chan W, Fornwald J, Brawner M, Wetzel, R. 1996. Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide A beta. Biochemistry 35:7123-7130.
-
(1996)
Biochemistry
, vol.35
, pp. 7123-7130
-
-
Chan, W.1
Fornwald, J.2
Brawner, M.3
Wetzel, R.4
-
15
-
-
0030039871
-
Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease
-
Christie RH, Freeman M, Hyman BT. 1996. Expression of the macrophage scavenger receptor, a multifunctional lipoprotein receptor, in microglia associated with senile plaques in Alzheimer's disease. Am J Pathol 148:399-403.
-
(1996)
Am J Pathol
, vol.148
, pp. 399-403
-
-
Christie, R.H.1
Freeman, M.2
Hyman, B.T.3
-
16
-
-
0031785364
-
Effect of chloroquine and leupeptin on intracellular accumulatin of amyloid-beta (A beta) 1-42 peptide in a murine N9 microglial cell line
-
Chu T, Tran T, Yang F, Beech W, Cole GM, Frautschy SA. 1998. Effect of chloroquine and leupeptin on intracellular accumulatin of amyloid-beta (A beta) 1-42 peptide in a murine N9 microglial cell line. FEBS Lett 436:439-444.
-
(1998)
FEBS Lett
, vol.436
, pp. 439-444
-
-
Chu, T.1
Tran, T.2
Yang, F.3
Beech, W.4
Cole, G.M.5
Frautschy, S.A.6
-
17
-
-
85165082230
-
Lipoprotein-dependent Aβ clearance in vivo and in vitro
-
Chu TS, Frautschy SA, Yang F, Teter B, Chen P, Beech W, Sigel JJ, Howard BD, Cole GM. 1997. Lipoprotein-dependent Aβ clearance in vivo and in vitro. Soc Neurosci Abstr 23: 1638.
-
(1997)
Soc Neurosci Abstr
, vol.23
, pp. 1638
-
-
Chu, T.S.1
Frautschy, S.A.2
Yang, F.3
Teter, B.4
Chen, P.5
Beech, W.6
Sigel, J.J.7
Howard, B.D.8
Cole, G.M.9
-
18
-
-
0033527637
-
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid β-peptide by microglial cells. 1999
-
Chung H, Brazil MI, Soe TT, Maxfield FR. 1999. Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid β-peptide by microglial cells. 1999. J Biol Chem 274:32301-32308.
-
(1999)
J Biol Chem
, vol.274
, pp. 32301-32308
-
-
Chung, H.1
Brazil, M.I.2
Soe, T.T.3
Maxfield, F.R.4
-
19
-
-
0033566370
-
Lipoprotein effects on Aβ accumulation and degradation by microglia in vitro
-
Cole GM, Beech W, Frautschy SA, Sigel J, Glasgow C, Ard MD. 1999. Lipoprotein effects on Aβ accumulation and degradation by microglia in vitro. J Neurosci Res 57: 504-520.
-
(1999)
J Neurosci Res
, vol.57
, pp. 504-520
-
-
Cole, G.M.1
Beech, W.2
Frautschy, S.A.3
Sigel, J.4
Glasgow, C.5
Ard, M.D.6
-
20
-
-
0028305380
-
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease
-
Corder EH, Saunders AM, Risch NJ, Strittmatter WJ, Schmechel DE, Gaskell PC, Rimmler JB, Locke PA, Conneally PM, Schmader KE, Small GW, Roses AD, Haines JL, Pericak-Vance MA. 1994. Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease. Nature Genet 7: 180-183.
-
(1994)
Nature Genet
, vol.7
, pp. 180-183
-
-
Corder, E.H.1
Saunders, A.M.2
Risch, N.J.3
Strittmatter, W.J.4
Schmechel, D.E.5
Gaskell, P.C.6
Rimmler, J.B.7
Locke, P.A.8
Conneally, P.M.9
Schmader, K.E.10
Small, G.W.11
Roses, A.D.12
Haines, J.L.13
Pericak-Vance, M.A.14
-
21
-
-
0032571154
-
Abnormal content of n-6 and n-3 long-chain fatty acids in the phosphoglycerides and cholesterol esters of parahippocampal cortex from Alzheimer's disease patients and its relationship to acetyl CoA content
-
Corrigan FM, Horrobin DF, Skinner ER, Besson JA, Cooper MB. 1998. Abnormal content of n-6 and n-3 long-chain fatty acids in the phosphoglycerides and cholesterol esters of parahippocampal cortex from Alzheimer's disease patients and its relationship to acetyl CoA content. Int J Biochem Cell Biol 30: 197-207.
-
(1998)
Int J Biochem Cell Biol
, vol.30
, pp. 197-207
-
-
Corrigan, F.M.1
Horrobin, D.F.2
Skinner, E.R.3
Besson, J.A.4
Cooper, M.B.5
-
22
-
-
0028801220
-
Lysosomal degradation and sorting of apolipoprotein E in macrophages
-
Deng J, Rudick V, Dory L. 1995. Lysosomal degradation and sorting of apolipoprotein E in macrophages. J Lipid Res 36:2129-2140.
-
(1995)
J Lipid Res
, vol.36
, pp. 2129-2140
-
-
Deng, J.1
Rudick, V.2
Dory, L.3
-
23
-
-
0030669036
-
The pathogenesis of senile plaques
-
Dickson DW. 1997. The pathogenesis of senile plaques. J Neuropathol Exp Neurol 56:321-339.
-
(1997)
J Neuropathol Exp Neurol
, vol.56
, pp. 321-339
-
-
Dickson, D.W.1
-
24
-
-
0027354484
-
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease
-
Dickson DW, Lee SC, Mattiace LA, Yen SC, Brosnan C. 1993. Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7:75-83.
-
(1993)
Glia
, vol.7
, pp. 75-83
-
-
Dickson, D.W.1
Lee, S.C.2
Mattiace, L.A.3
Yen, S.C.4
Brosnan, C.5
-
25
-
-
0029787599
-
Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils
-
El Khoury J, Hickman SE, Thomas CA, Cao L, Silverstein SC, Loike JD. 1996. Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils. Nature 382:716-719.
-
(1996)
Nature
, vol.382
, pp. 716-719
-
-
El Khoury, J.1
Hickman, S.E.2
Thomas, C.A.3
Cao, L.4
Silverstein, S.C.5
Loike, J.D.6
-
26
-
-
0032893154
-
Appearance of sodium dodecyl sulfate-stable amyloid β-protein (Aβ) dimer in the cortex during aging
-
Enya M, Morishima-Kawashima M, Shinkai Y, Kusui K, Khan K, Games D, Schenk D, Sugihara S, Yamaguchi H, Ihara Y. 1999. Appearance of sodium dodecyl sulfate-stable amyloid β-protein (Aβ) dimer in the cortex during aging. Am J Pathol 154:271-279.
-
(1999)
Am J Pathol
, vol.154
, pp. 271-279
-
-
Enya, M.1
Morishima-Kawashima, M.2
Shinkai, Y.3
Kusui, K.4
Khan, K.5
Games, D.6
Schenk, D.7
Sugihara, S.8
Yamaguchi, H.9
Ihara, Y.10
-
27
-
-
0028872558
-
Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implicatioins for the pathogenesis and treatment of alzheimer disease
-
Evans KC, Berger EP, Cho CG, Weisgraber KH, Lansbury PT. 1995. Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: Implicatioins for the pathogenesis and treatment of alzheimer disease. Proc Natl Acad Sci USA 92:763-767.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 763-767
-
-
Evans, K.C.1
Berger, E.P.2
Cho, C.G.3
Weisgraber, K.H.4
Lansbury, P.T.5
-
28
-
-
85164997520
-
Lipoprotein profiles of normal human cerebrospinal fluid of known APOE genotype
-
Fagan AM, Younkin LH, Morris JC, Phillips K, Younkin SG, Holtzman DM. 1999. Lipoprotein profiles of normal human cerebrospinal fluid of known APOE genotype. Soc Neurosci Abstr 25:1348.
-
(1999)
Soc Neurosci Abstr
, vol.25
, pp. 1348
-
-
Fagan, A.M.1
Younkin, L.H.2
Morris, J.C.3
Phillips, K.4
Younkin, S.G.5
Holtzman, D.M.6
-
29
-
-
0000892596
-
High density lipoprotein decreases β-amyloid toxicity in cortical cell culture
-
Farhangrazi ZS, Ying H, Bu G, Dugan LL, Fagan AM, Choi DW, Holtzman DM. 1997. High density lipoprotein decreases β-amyloid toxicity in cortical cell culture. Neuroreport 8:1127-1130.
-
(1997)
Neuroreport
, vol.8
, pp. 1127-1130
-
-
Farhangrazi, Z.S.1
Ying, H.2
Bu, G.3
Dugan, L.L.4
Fagan, A.M.5
Choi, D.W.6
Holtzman, D.M.7
-
30
-
-
0026783591
-
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils
-
Berl
-
Frackowiak J, Wisniewski HM, Wegiel J, Merz GS, Iqbal K, Wang KC. 1992. Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils. Acta Neuropathol (Berl) 84:225-233.
-
(1992)
Acta Neuropathol
, vol.84
, pp. 225-233
-
-
Frackowiak, J.1
Wisniewski, H.M.2
Wegiel, J.3
Merz, G.S.4
Iqbal, K.5
Wang, K.C.6
-
31
-
-
0026635173
-
Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid
-
Frautschy SA, Cole GM, Baird A. 1992. Phagocytosis and deposition of vascular beta-amyloid in rat brains injected with Alzheimer beta-amyloid. Am J Pathol 140:1389-1399.
-
(1992)
Am J Pathol
, vol.140
, pp. 1389-1399
-
-
Frautschy, S.A.1
Cole, G.M.2
Baird, A.3
-
32
-
-
0029664434
-
Aβ-peptide length and apolipoprotein E genotype in Alzheimer's disease
-
Gearing M, Mori H, Mirra SS. 1996. Aβ-peptide length and apolipoprotein E genotype in Alzheimer's disease. Ann Neurol 39:395-399.
-
(1996)
Ann Neurol
, vol.39
, pp. 395-399
-
-
Gearing, M.1
Mori, H.2
Mirra, S.S.3
-
33
-
-
85165073250
-
Fate of cerebrospinal fluid-borne amyloid beta-peptide: Rapid clearance into blood and appreciable accumulation by cerebral arteries
-
Ghersi-Egea JF, Gorevic PD, Ghiso J, Frangione B, Patlak CS, Fenstennacher JD. 1996. Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem 93:2312-2316.
-
(1996)
J Neurochem
, vol.93
, pp. 2312-2316
-
-
Ghersi-Egea, J.F.1
Gorevic, P.D.2
Ghiso, J.3
Frangione, B.4
Patlak, C.S.5
Fenstennacher, J.D.6
-
34
-
-
0027186334
-
The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex
-
Ghiso J, Matsubara E, Koudinov A, Choi-Miura NH, Tomita M, Wisniewski T, Frangione B. 1993. The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex. Biochem J 293: 27-30.
-
(1993)
Biochem J
, vol.293
, pp. 27-30
-
-
Ghiso, J.1
Matsubara, E.2
Koudinov, A.3
Choi-Miura, N.H.4
Tomita, M.5
Wisniewski, T.6
Frangione, B.7
-
35
-
-
0029063033
-
Amyloid binding proteins in vitro and in normal human cerebrospinal fluid
-
Golabek A, Marques MA, Lalowski M, and Wisniewski T. 1995. Amyloid binding proteins in vitro and in normal human cerebrospinal fluid. Neurosci Lett 191:79-82.
-
(1995)
Neurosci Lett
, vol.191
, pp. 79-82
-
-
Golabek, A.1
Marques, M.A.2
Lalowski, M.3
Wisniewski, T.4
-
36
-
-
0022449937
-
Abnormal in vivo metabolism of apolipoprotein E4 in humans
-
Gregg RE, Zech LA, Schaefer EJ, Stark D, Wilson D, Brewer HB. 1986. Abnormal in vivo metabolism of apolipoprotein E4 in humans. J Clin Invest 78:815-821.
-
(1986)
J Clin Invest
, vol.78
, pp. 815-821
-
-
Gregg, R.E.1
Zech, L.A.2
Schaefer, E.J.3
Stark, D.4
Wilson, D.5
Brewer, H.B.6
-
37
-
-
0030753654
-
Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide
-
Hammad SM, Ranganathan S, Loukinova E, Twal WO, Argraves WS. 1997. Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide. J Biol Chem 272:18644-18649.
-
(1997)
J Biol Chem
, vol.272
, pp. 18644-18649
-
-
Hammad, S.M.1
Ranganathan, S.2
Loukinova, E.3
Twal, W.O.4
Argraves, W.S.5
-
38
-
-
0028641565
-
Role of HDL apolipoprotein E in cellular cholesterol efflux: Studies in apo E knockout transgenic mice
-
Hayek T, Oiknine J, Brook JG, Aviram M. 1994. Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice. Biochem Biophys Res Commun 205:1072-1078.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1072-1078
-
-
Hayek, T.1
Oiknine, J.2
Brook, J.G.3
Aviram, M.4
-
39
-
-
0031778408
-
Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease
-
Hollenbach E, Ackerman S, Hyman BT, Rebeck GW. 1998. Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease. Neurology 50:1905-1907.
-
(1998)
Neurology
, vol.50
, pp. 1905-1907
-
-
Hollenbach, E.1
Ackerman, S.2
Hyman, B.T.3
Rebeck, G.W.4
-
40
-
-
0033559412
-
Expression of human apolipoprotein E reduces amyloid-B deposition in a mouse model of Alzheimer's disease
-
Holtzman DM, Bales RK, Wu S, Bhat P, Parsadanian M, Fagan AM, Chang LK, Sun Y, Paul SM. 1999. Expression of human apolipoprotein E reduces amyloid-B deposition in a mouse model of Alzheimer's disease. J Clin Invest 103:R15-R21.
-
(1999)
J Clin Invest
, vol.103
-
-
Holtzman, D.M.1
Bales, R.K.2
Wu, S.3
Bhat, P.4
Parsadanian, M.5
Fagan, A.M.6
Chang, L.K.7
Sun, Y.8
Paul, S.M.9
-
41
-
-
0032576963
-
Immunohistochemical evidence for a macrophage scavenger receptor in Mato cells and reactive microglia of ischemia and Alzheimer's disease
-
Honda M, Akiyama H, Yamada Y, Kondo H, Kawabe Y, Takeya M, Takahashi K, Suzuki H, Doi T, Sakamoto A, Ookawara S, Mato M, Gough PJ, Greaves DR, Gordon S, Kodama T, Matsushita M. 1998. Immunohistochemical evidence for a macrophage scavenger receptor in Mato cells and reactive microglia of ischemia and Alzheimer's disease. Biochem Biophys Res Commun 245:734-740.
-
(1998)
Biochem Biophys Res Commun
, vol.245
, pp. 734-740
-
-
Honda, M.1
Akiyama, H.2
Yamada, Y.3
Kondo, H.4
Kawabe, Y.5
Takeya, M.6
Takahashi, K.7
Suzuki, H.8
Doi, T.9
Sakamoto, A.10
Ookawara, S.11
Mato, M.12
Gough, P.J.13
Greaves, D.R.14
Gordon, S.15
Kodama, T.16
Matsushita, M.17
-
42
-
-
85165103951
-
Apolipoprotein E: Clinical, pathological, and biochemical correlations in Alzheimer's disease
-
Yankner BA and Roses AD, editors. Keystone Symposia on Molecular and Cellular Biology, Tamarron, Colorado
-
Hyman B. 1997. Apolipoprotein E: Clinical, pathological, and biochemical correlations in Alzheimer's disease. In: Yankner BA and Roses AD, editors. Molecular mechanisms in Alzheimer's disease. Keystone Symposia on Molecular and Cellular Biology, Tamarron, Colorado, p. 5.
-
(1997)
Molecular Mechanisms in Alzheimer's Disease
, pp. 5
-
-
Hyman, B.1
-
43
-
-
0027490070
-
The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution
-
Hyman BT, Marzloff K, Arriagada PV. 1993. The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution. J Neuropathol Exp Neurol 52:594-600.
-
(1993)
J Neuropathol Exp Neurol
, vol.52
, pp. 594-600
-
-
Hyman, B.T.1
Marzloff, K.2
Arriagada, P.V.3
-
44
-
-
0030615092
-
Aβ1-40 but not Aβ1-42 levels in cortex correlate with apolipoprotein E E4 allele dosage in sporadic Alzheimer's disease
-
Ishii K, Tamaoka A, Mizusawa H, Shoji S, Ohtake T, Fraser PE, Takahashi H, Tsuji S, Gearing M, Mizutani T, Yamada S, Kato M, St. George-Hyslop PH, Mirra SS, Mori H. 1997. Aβ1-40 but not Aβ1-42 levels in cortex correlate with apolipoprotein E E4 allele dosage in sporadic Alzheimer's disease. Brain Res 748: 250-252.
-
(1997)
Brain Res
, vol.748
, pp. 250-252
-
-
Ishii, K.1
Tamaoka, A.2
Mizusawa, H.3
Shoji, S.4
Ohtake, T.5
Fraser, P.E.6
Takahashi, H.7
Tsuji, S.8
Gearing, M.9
Mizutani, T.10
Yamada, S.11
Kato, M.12
St George-Hyslop, P.H.13
Mirra, S.S.14
Mori, H.15
-
45
-
-
0033621739
-
Identification of the major Aβ1-42 degrading catabolic pathway in brain parenychyma: Suppression leads to biochemical and pathological deposition
-
Iwata N, Tsubuki S, Takaki Y, Watanabe, K., Sekiguchi M, Hosoki E, Watanabe K, Morishima-Kawashima M, Lee HJ , Hama, E., Sekine-Aizawa, Y., Saido TC. 2000. Identification of the major Aβ1-42 degrading catabolic pathway in brain parenychyma: Suppression leads to biochemical and pathological deposition. Nature Med 6:143-150.
-
(2000)
Nature Med
, vol.6
, pp. 143-150
-
-
Iwata, N.1
Tsubuki, S.2
Takaki, Y.3
Watanabe, K.4
Sekiguchi, M.5
Hosoki, E.6
Watanabe, K.7
Morishima-Kawashima, M.8
Lee, H.J.9
Hama, E.10
Sekine-Aizawa, Y.11
Saido, T.C.12
-
46
-
-
0031963852
-
Isoform-specific effect of apolipoprotein E on cell survival and β-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures
-
Jordan J, Galindo MF, Miller RJ, Reardon CA, Getz GS, LaDu MJ. 1998. Isoform-specific effect of apolipoprotein E on cell survival and β-amyloid-induced toxicity in rat hippocampal pyramidal neuronal cultures. J Neurosci 18:195-204.
-
(1998)
J Neurosci
, vol.18
, pp. 195-204
-
-
Jordan, J.1
Galindo, M.F.2
Miller, R.J.3
Reardon, C.A.4
Getz, G.S.5
LaDu, M.J.6
-
47
-
-
0032904130
-
Microglia and Alzheimer's disease
-
Kalaria RN. 1999. Microglia and Alzheimer's disease. Curr Opin Hematol 6:15-24.
-
(1999)
Curr Opin Hematol
, vol.6
, pp. 15-24
-
-
Kalaria, R.N.1
-
48
-
-
0031148272
-
Alzheimer's soluble amyloid beta protein is secreted by HepG2 cells as an apolipoprotein
-
Koudinov AR, Koudinova NV. 1997. Alzheimer's soluble amyloid beta protein is secreted by HepG2 cells as an apolipoprotein. Cell Biol Int 21:265-271.
-
(1997)
Cell Biol Int
, vol.21
, pp. 265-271
-
-
Koudinov, A.R.1
Koudinova, N.V.2
-
49
-
-
0028609448
-
The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma
-
Koudinov A, Matsubara E, Frangione B, Ghiso J. 1994. The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem Biophys Res Commun 205:1164-1171.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1164-1171
-
-
Koudinov, A.1
Matsubara, E.2
Frangione, B.3
Ghiso, J.4
-
50
-
-
0030601055
-
Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: Association with high density lipoproteins
-
Koudinov AR, Koudinova NV, Kumar A, Beavis RC, Ghiso J. 1996. Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: Association with high density lipoproteins. Biochem Biophys Res Commun 223:592-597.
-
(1996)
Biochem Biophys Res Commun
, vol.223
, pp. 592-597
-
-
Koudinov, A.R.1
Koudinova, N.V.2
Kumar, A.3
Beavis, R.C.4
Ghiso, J.5
-
51
-
-
0032559575
-
Alzheimer's amyloid β interaction with normal human plasma high density lipoprotein: Association with apolipoprotein and lipids
-
Koudinov AR, Berezov TT, Kumar A, Koudinova NV. 1998. Alzheimer's amyloid β interaction with normal human plasma high density lipoprotein: association with apolipoprotein and lipids. Clin Chim Acta 270:75-84.
-
(1998)
Clin Chim Acta
, vol.270
, pp. 75-84
-
-
Koudinov, A.R.1
Berezov, T.T.2
Kumar, A.3
Koudinova, N.V.4
-
52
-
-
0030597061
-
Multiple inhibitory effects of Alzheimer's peptide Abeta1-40 on lipid biosynthesis in cultured human HepG2 cells
-
Koudinova NV, Berezov TT, Koudinov AR. 1996. Multiple inhibitory effects of Alzheimer's peptide Abeta1-40 on lipid biosynthesis in cultured human HepG2 cells. FEBS Lett 393:204-206.
-
(1996)
FEBS Lett
, vol.393
, pp. 204-206
-
-
Koudinova, N.V.1
Berezov, T.T.2
Koudinov, A.R.3
-
53
-
-
0028959817
-
Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophages
-
Kruth HS, Scarlatos HI, Lilly K, Chang J, Ifrim I. 1995. Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophages. J Cell Biol 129:133-145.
-
(1995)
J Cell Biol
, vol.129
, pp. 133-145
-
-
Kruth, H.S.1
Scarlatos, H.I.2
Lilly, K.3
Chang, J.4
Ifrim, I.5
-
54
-
-
0029671451
-
Water-soluble Aβ (N-40, N-42) oligomers in normal and Alzheimer disease brains
-
Kuo Y-M, Emmerling MR, Vigo-Pelfrey C, Kasunic TC, Kirkpatrick JB, Murdoch GH, Ball MJ, Roher AE. 1996. Water-soluble Aβ (N-40, N-42) oligomers in normal and Alzheimer disease brains. J Biol Chem 271:4077-4081.
-
(1996)
J Biol Chem
, vol.271
, pp. 4077-4081
-
-
Kuo, Y.-M.1
Emmerling, M.R.2
Vigo-Pelfrey, C.3
Kasunic, T.C.4
Kirkpatrick, J.B.5
Murdoch, G.H.6
Ball, M.J.7
Roher, A.E.8
-
55
-
-
0027931854
-
Isoform-specific binding of apolipoprotein E to β-amyloid
-
LaDu MJ, Falduto MT, Manelli AM, Reardon CA, Getz GS, Frail DE. 1994. Isoform-specific binding of apolipoprotein E to β-amyloid. J Biol Chem 269:23403-23406.
-
(1994)
J Biol Chem
, vol.269
, pp. 23403-23406
-
-
LaDu, M.J.1
Falduto, M.T.2
Manelli, A.M.3
Reardon, C.A.4
Getz, G.S.5
Frail, D.E.6
-
56
-
-
0028906808
-
Purification of Apolipoprotein E attenuates isoform-specific binding to β-amyloid
-
LaDu MJ, Pederson TM, Frail DE, Reardon CA, Getz GS, Falduto MT. 1995. Purification of Apolipoprotein E attenuates isoform-specific binding to β-amyloid. J Biol Chem 270:9039-9042.
-
(1995)
J Biol Chem
, vol.270
, pp. 9039-9042
-
-
Ladu, M.J.1
Pederson, T.M.2
Frail, D.E.3
Reardon, C.A.4
Getz, G.S.5
Falduto, M.T.6
-
57
-
-
0031970198
-
Nascent astrocyte particles differ from lipoproteins in CSF
-
LaDu MJ, Gilligan SM, Lukens JR, Cabana VG, Reardon CA, Van Eldik LJ, Holtzman DM. 1998. Nascent astrocyte particles differ from lipoproteins in CSF. J Neurochem 70:2070-2081.
-
(1998)
J Neurochem
, vol.70
, pp. 2070-2081
-
-
Ladu, M.J.1
Gilligan, S.M.2
Lukens, J.R.3
Cabana, V.G.4
Reardon, C.A.5
Van Eldik, L.J.6
Holtzman, D.M.7
-
59
-
-
0030894679
-
Matrix metalloproteinases in dog brains exhibiting Alzheimer-like characteristics
-
Lim GP, Russell MJ, Cullen MJ, Tokes ZA. 1997. Matrix metalloproteinases in dog brains exhibiting Alzheimer-like characteristics. J Neurochem 68:1606-1611.
-
(1997)
J Neurochem
, vol.68
, pp. 1606-1611
-
-
Lim, G.P.1
Russell, M.J.2
Cullen, M.J.3
Tokes, Z.A.4
-
60
-
-
0032573097
-
Amyloid β peptide alters intracellular vesicle trafficking and cholesterol homeostasis
-
Liu Y, Peterson DA, Schubert D. 1998. Amyloid β peptide alters intracellular vesicle trafficking and cholesterol homeostasis. Proc Natl Acad Sci USA 95:13266-13271.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13266-13271
-
-
Liu, Y.1
Peterson, D.A.2
Schubert, D.3
-
61
-
-
0029934992
-
Cell surface proteoglycans modulate net synthesis and secretion of macrophage apolipoprotein E
-
Lucas M, Mazzone T. 1996. Cell surface proteoglycans modulate net synthesis and secretion of macrophage apolipoprotein E. J Biol Chems 271:13454-13459
-
(1996)
J Biol Chems
, vol.271
, pp. 13454-13459
-
-
Lucas, M.1
Mazzone, T.2
-
62
-
-
0028173205
-
1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments
-
1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments. Nature 372: 92-94.
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer Jr., H.B.3
Das, S.4
Potter, H.5
-
63
-
-
0030175843
-
Heparan sulfate proteoglycan/low density lipoprotein receptor-related protein pathway involved in type III hyperlipoproteinemia and Alzheimer's disease
-
Mahley RW. 1996. Heparan sulfate proteoglycan/low density lipoprotein receptor-related protein pathway involved in type III hyperlipoproteinemia and Alzheimer's disease. Isr J Med Sci 32:414-29.
-
(1996)
Isr J Med Sci
, vol.32
, pp. 414-429
-
-
Mahley, R.W.1
-
64
-
-
85165103951
-
Apolipoprotein E: Structure, function, and possible roles in neurodegenerative disease
-
Yankner B, Roses AD, editors. Keystone Symposia on Molecular and Cellular Biology, Tamarron, Colorado
-
Mahley RW. 1997. Apolipoprotein E: Structure, function, and possible roles in neurodegenerative disease. In: Yankner B, Roses AD, editors. Molecular mechanisms in Alzheimer's disease. Keystone Symposia on Molecular and Cellular Biology, Tamarron, Colorado, p. 5.
-
(1997)
Molecular Mechanisms in Alzheimer's Disease
, pp. 5
-
-
Mahley, R.W.1
-
65
-
-
0029924266
-
Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease
-
Mahley RW, Nathan BP, Pitas RE. 1996. Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease. Ann NY Acad Sci 777:139-145.
-
(1996)
Ann NY Acad Sci
, vol.777
, pp. 139-145
-
-
Mahley, R.W.1
Nathan, B.P.2
Pitas, R.E.3
-
66
-
-
0343247789
-
Preferential deposition of amyloid β protein (Aβ) in the form of Aβ40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E E4 allele
-
Mann DMA, Iwatsubo T, Pickering-Brown SM, Owen F, Saido TC, Perry RH. 1997. Preferential deposition of amyloid β protein (Aβ) in the form of Aβ40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E E4 allele. Neurosci Lett 221: 81-84.
-
(1997)
Neurosci Lett
, vol.221
, pp. 81-84
-
-
Mann, D.M.A.1
Iwatsubo, T.2
Pickering-Brown, S.M.3
Owen, F.4
Saido, T.C.5
Perry, R.H.6
-
67
-
-
0030014990
-
Apolipoprotein J and Alzheimer's amyloid β solubility
-
Matsubara E, Soto C, Governale S, Frangione B, Ghiso J. 1996. Apolipoprotein J and Alzheimer's amyloid β solubility. Biochem J 316:671-679.
-
(1996)
Biochem J
, vol.316
, pp. 671-679
-
-
Matsubara, E.1
Soto, C.2
Governale, S.3
Frangione, B.4
Ghiso, J.5
-
68
-
-
0025339720
-
Detection of HLA-DR on microglia in the human brain is a function of both clinical and technical factors
-
Mattiace LA, Davies P, Dickson DW. 1990. Detection of HLA-DR on microglia in the human brain is a function of both clinical and technical factors. Am J Pathol 136:1101-1114.
-
(1990)
Am J Pathol
, vol.136
, pp. 1101-1114
-
-
Mattiace, L.A.1
Davies, P.2
Dickson, D.W.3
-
69
-
-
0032487648
-
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites
-
Mattson MP, Partin J, Begley JG. 1998. Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites. Brain Res 807: 167-76.
-
(1998)
Brain Res
, vol.807
, pp. 167-176
-
-
Mattson, M.P.1
Partin, J.2
Begley, J.G.3
-
70
-
-
0028103803
-
Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3
-
Mazzone T, Reardon C. 1994. Expression of heterologous human apolipoprotein E by J774 macrophages enhances cholesterol efflux to HDL3. J Lipid Res 35:1345-1353.
-
(1994)
J Lipid Res
, vol.35
, pp. 1345-1353
-
-
Mazzone, T.1
Reardon, C.2
-
71
-
-
0030961544
-
Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia
-
McDonald DR, Brunden KR, Landreth GE. 1997. Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia. J Neurosci 17:2284-2294.
-
(1997)
J Neurosci
, vol.17
, pp. 2284-2294
-
-
McDonald, D.R.1
Brunden, K.R.2
Landreth, G.E.3
-
72
-
-
0032526423
-
β-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes
-
McDonald DR, Bamberger ME, Combs CK, Landreth GE. 1998. β-Amyloid fibrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes. J Neurosci 18:4451-4460.
-
(1998)
J Neurosci
, vol.18
, pp. 4451-4460
-
-
McDonald, D.R.1
Bamberger, M.E.2
Combs, C.K.3
Landreth, G.E.4
-
73
-
-
0030830113
-
Deposition of amyloid beta protein (Aβ) subtypes [Aβ40 and Aβ42(43)] in canine senile plaques and cerebral amyloid angiopathy
-
Berl
-
Nakamura S, Tamaoka A, Sawamura N, Kiatipattanasakul W, Nakayama H, Shoji S, Yoshikawa Y, Doi K. 1997. Deposition of amyloid beta protein (Aβ) subtypes [Aβ40 and Aβ42(43)] in canine senile plaques and cerebral amyloid angiopathy. Acta Neuropathol (Berl) 94: 323-328.
-
(1997)
Acta Neuropathol
, vol.94
, pp. 323-328
-
-
Nakamura, S.1
Tamaoka, A.2
Sawamura, N.3
Kiatipattanasakul, W.4
Nakayama, H.5
Shoji, S.6
Yoshikawa, Y.7
Doi, K.8
-
74
-
-
0026601368
-
Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with alzheimer's disease
-
Namba Y, Tsuchiya H, Ikeda K. 1992. Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with alzheimer's disease. Neurosci Lett 134:264-266.
-
(1992)
Neurosci Lett
, vol.134
, pp. 264-266
-
-
Namba, Y.1
Tsuchiya, H.2
Ikeda, K.3
-
75
-
-
0038117796
-
Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
-
Naslund J, Haroutunian V, Mohs R, Davis KL, Davies P, Greengard P, Buxbaum JD. 2000. Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline. JAMA 283:1571-1577.
-
(2000)
JAMA
, vol.283
, pp. 1571-1577
-
-
Naslund, J.1
Haroutunian, V.2
Mohs, R.3
Davis, K.L.4
Davies, P.5
Greengard, P.6
Buxbaum, J.D.7
-
76
-
-
0028986690
-
Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury
-
Nicoll JA, Roberts GW, Graham DI. 1995. Apolipoprotein E epsilon 4 allele is associated with deposition of amyloid beta-protein following head injury. Nat Med 1:135-137.
-
(1995)
Nat Med
, vol.1
, pp. 135-137
-
-
Nicoll, J.A.1
Roberts, G.W.2
Graham, D.I.3
-
77
-
-
0031044513
-
Distribution of apolipoprotein E in senile plaques in brains with alzheimer's disease: Investigation with the confocal laser scan microscope
-
Nishiyama E, Iwamoto N, Ohwada J, Arai H. 1997. Distribution of apolipoprotein E in senile plaques in brains with alzheimer's disease: investigation with the confocal laser scan microscope. Brain Res 750:20-24.
-
(1997)
Brain Res
, vol.750
, pp. 20-24
-
-
Nishiyama, E.1
Iwamoto, N.2
Ohwada, J.3
Arai, H.4
-
78
-
-
0030248270
-
Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor
-
Paresce DM, Ghosh RN, Maxfield FR. 1996. Microglial cells internalize aggregates of the Alzheimer's disease amyloid β-protein via a scavenger receptor. Neuron 17:553-565.
-
(1996)
Neuron
, vol.17
, pp. 553-565
-
-
Paresce, D.M.1
Ghosh, R.N.2
Maxfield, F.R.3
-
79
-
-
0030664076
-
Slow degradation of aggregates of the Alzheimer's disease amyloid β-protein by microglial cells
-
Paresce DM, Chung H, Maxfield FR. 1997. Slow degradation of aggregates of the Alzheimer's disease amyloid β-protein by microglial cells. J Biol Chem 46:29390-29397.
-
(1997)
J Biol Chem
, vol.46
, pp. 29390-29397
-
-
Paresce, D.M.1
Chung, H.2
Maxfield, F.R.3
-
80
-
-
0031587429
-
Detection of apolipoprotein E dimeric soluble amyloid β complexes in Alzheimer's disease brain supernatants
-
Permanne B, Perez C, Soto C, Frangione B, Wisniewski T. 1997. Detection of apolipoprotein E dimeric soluble amyloid β complexes in Alzheimer's disease brain supernatants. Biochem Biophys Res Commun 240:715-720.
-
(1997)
Biochem Biophys Res Commun
, vol.240
, pp. 715-720
-
-
Permanne, B.1
Perez, C.2
Soto, C.3
Frangione, B.4
Wisniewski, T.5
-
81
-
-
0000840277
-
Aβ40 and Aβ42 clearance in a transgenic mouse model expressing human ApoE3 and ApoE4
-
Permanne B, Ji Y, Holtzman D, Frangione B, Wisniewski T. 1999. Aβ40 and Aβ42 clearance in a transgenic mouse model expressing human ApoE3 and ApoE4. Soc Neurosci Abstr 25:1058.
-
(1999)
Soc Neurosci Abstr
, vol.25
, pp. 1058
-
-
Permanne, B.1
Ji, Y.2
Holtzman, D.3
Frangione, B.4
Wisniewski, T.5
-
82
-
-
0023280054
-
Lipoproteins and their receptors in the central nervous system
-
Pitas RE, Boyles JK, Lee SH, Hui D, Weisgraber KH. 1987. Lipoproteins and their receptors in the central nervous system. J Biol Chem 262:14352-14360.
-
(1987)
J Biol Chem
, vol.262
, pp. 14352-14360
-
-
Pitas, R.E.1
Boyles, J.K.2
Lee, S.H.3
Hui, D.4
Weisgraber, K.H.5
-
84
-
-
0031914130
-
Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes
-
Rebeck GW, Alonzo NC, Berezovska O, Harr SD, Knowles RB, Growdon JH, Hyman BT, Mendez AJ. 1998. Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes. Exp Neurol 149:175-182.
-
(1998)
Exp Neurol
, vol.149
, pp. 175-182
-
-
Rebeck, G.W.1
Alonzo, N.C.2
Berezovska, O.3
Harr, S.D.4
Knowles, R.B.5
Growdon, J.H.6
Hyman, B.T.7
Mendez, A.J.8
-
85
-
-
13044309464
-
Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease
-
Russo C, Angelini G, Dapino D, Piccini A, Piombo G, Schettini G, Chen S, Teller JK, Zaccheo D, Gambetti M, Tabaton M. 1998. Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease. Proc Natl Acad Sci 95: 15598-15602.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 15598-15602
-
-
Russo, C.1
Angelini, G.2
Dapino, D.3
Piccini, A.4
Piombo, G.5
Schettini, G.6
Chen, S.7
Teller, J.K.8
Zaccheo, D.9
Gambetti, M.10
Tabaton, M.11
-
86
-
-
0028026587
-
Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils
-
Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD, Strittmatter WJ. 1994. Apolipoprotein E associates with β amyloid peptide of Alzheimer's disease to form novel monofibrils. J Clin Invest 94: 860-869.
-
(1994)
J Clin Invest
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
Saunders, A.6
Schmechel, D.7
Wisniewski, T.8
Frangione, B.9
Roses, A.D.10
Strittmatter, W.J.11
-
87
-
-
0027337858
-
Apolipoprotein E E4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases
-
Saunders AM, Schmader K, Breitner JCS, Benson MD, Brown WT, Goldfarb L, Goldgaber D, Manwaring MG, Szymanski MH, McCown N, Dole KC, Schmechel DE, Strittmatter WJ, Pericak-Vance MA, Roses AD. 1993. Apolipoprotein E E4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. Lancet 342:710-711.
-
(1993)
Lancet
, vol.342
, pp. 710-711
-
-
Saunders, A.M.1
Schmader, K.2
Jcs, B.3
Benson, M.D.4
Brown, W.T.5
Goldfarb, L.6
Goldgaber, D.7
Manwaring, M.G.8
Szymanski, M.H.9
McCown, N.10
Dole, K.C.11
Schmechel, D.E.12
Strittmatter, W.J.13
Pericak-Vance, M.A.14
Roses, A.D.15
-
88
-
-
0032032493
-
Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester
-
Savage MJ, Trusko SP, Howland, DS, Pinsker LR, Mistretta S, Reaume AG, Greenberg BD, Siman R, Scott RW. 1998. Turnover of amyloid β-protein in mouse brain and acute reduction of its level by phorbol ester. J Neurosci 18:1743-1752.
-
(1998)
J Neurosci
, vol.18
, pp. 1743-1752
-
-
Savage, M.J.1
Trusko, S.P.2
Howland, D.S.3
Pinsker, L.R.4
Mistretta, S.5
Reaume, A.G.6
Greenberg, B.D.7
Siman, R.8
Scott, R.W.9
-
89
-
-
0033536163
-
Immunization with amyloid β attenuates Alzheimer-disease-like pathology in the PDAPP mouse
-
Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P. 1999. Immunization with amyloid β attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature 400:173-177.
-
(1999)
Nature
, vol.400
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guido, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
90
-
-
0027365822
-
Increased amyloid β-peptide deposition as a consequence of apolipoprotein E genotype in late-onset Alzheimers disease
-
Schmechel DE, Saunders AM, Strittmatter WJ, Crain B, Hulette C, Joo SH, Pericak-Vance MA, Goldgaber D, Roses AD. 1993. Increased amyloid β-peptide deposition as a consequence of apolipoprotein E genotype in late-onset Alzheimers disease. Proc Natl Acad Sci USA 90:9649-9653.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Crain, B.4
Hulette, C.5
Joo, S.H.6
Pericak-Vance, M.A.7
Goldgaber, D.8
Roses, A.D.9
-
91
-
-
0027999030
-
Transthyretin sequesters amyloid β protein and prevents amyloid formation
-
Schwarzman AL, Gregori L, Vitek MP, Lyubski S, Strittmatter WJ, Enghilde JJ, Bhasin R, Silverman J, Weisgraber KH, Coyle PK, Zagorski MG, Talafous J, Eisenberg M, Saunders AM, Roses AD, Goldgaber D. 1994. Transthyretin sequesters amyloid β protein and prevents amyloid formation. Proc Natl Acad Sci USA 91:8368-8372.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8368-8372
-
-
Schwarzman, A.L.1
Gregori, L.2
Vitek, M.P.3
Lyubski, S.4
Strittmatter, W.J.5
Enghilde, J.J.6
Bhasin, R.7
Silverman, J.8
Weisgraber, K.H.9
Coyle, P.K.10
Zagorski, M.G.11
Talafous, J.12
Eisenberg, M.13
Saunders, A.M.14
Roses, A.D.15
Goldgaber, D.16
-
92
-
-
0028849635
-
Amyloid β protein (Aβ) removal by neuroglial cells in culture
-
Shaffer LM, Dority MD, Gupta-Bansal R, Frederickson RCA, Younkin SG, Brunden KR. 1995. Amyloid β protein (Aβ) removal by neuroglial cells in culture. Neurobiol Aging 16:737-745.
-
(1995)
Neurobiol Aging
, vol.16
, pp. 737-745
-
-
Shaffer, L.M.1
Dority, M.D.2
Gupta-Bansal, R.3
Frederickson, R.C.A.4
Younkin, S.G.5
Brunden, K.R.6
-
93
-
-
0032568552
-
Cholesterol depletion inhibits the generation of β-amyloid in neurons
-
Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. 1998. Cholesterol depletion inhibits the generation of β-amyloid in neurons. Proc Natl Acad Sci USA 95:6460-6464.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6460-6464
-
-
Simons, M.1
Keller, P.2
De Strooper, B.3
Beyreuther, K.4
Dotti, C.G.5
Simons, K.6
-
94
-
-
0030058382
-
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the alzheimer β-amyloid peptide
-
Solomon B, Koppel R, Hanan E, Katzav T. 1996. Monoclonal antibodies inhibit in vitro fibrillar aggregation of the alzheimer β-amyloid peptide. Proc Natl Acad Sci USA 93:452-455.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 452-455
-
-
Solomon, B.1
Koppel, R.2
Hanan, E.3
Katzav, T.4
-
95
-
-
12044254746
-
Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
Strittmatter WJ, Weisgraber KH, Huang DY, Dong L-M, Salvesen GS, Pericak-Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD. 1993. Binding of human apolipoprotein E to synthetic amyloid β peptide: Isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci USA 90:8098-8102.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8098-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
Dong, L.-M.4
Salvesen, G.S.5
Pericak-Vance, M.6
Schmechel, D.7
Saunders, A.M.8
Goldgaber, D.9
Roses, A.D.10
-
96
-
-
0025077080
-
Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain
-
Styren SD, Civin WH, Rogers J. 1990. Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain. Exp Neurol 110:93-104.
-
(1990)
Exp Neurol
, vol.110
, pp. 93-104
-
-
Styren, S.D.1
Civin, W.H.2
Rogers, J.3
-
97
-
-
0028181396
-
Soluble amyloid beta-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid
-
Tabaton M, Nunzi MG, Xue R, Usiak M, Autilio-Gambetti L, Gambetti P. 1994. Soluble amyloid beta-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid. Biochem Biophys Res Commun 200:1598-1603.
-
(1994)
Biochem Biophys Res Commun
, vol.200
, pp. 1598-1603
-
-
Tabaton, M.1
Nunzi, M.G.2
Xue, R.3
Usiak, M.4
Autilio-Gambetti, L.5
Gambetti, P.6
-
98
-
-
0025335717
-
Reactive microglia express class I and class II major histocompatibility antigens in Alzheimer disease
-
Tooyama I, Kimura H, Akiyama H, McGeer PL. 1990. Reactive microglia express class I and class II major histocompatibility antigens in Alzheimer disease. Brain Res 523:273-280.
-
(1990)
Brain Res
, vol.523
, pp. 273-280
-
-
Tooyama, I.1
Kimura, H.2
Akiyama, H.3
McGeer, P.L.4
-
99
-
-
0030833577
-
Cerebrovascular smooth muscle cells internalize Alzheimer amyloid beta protein via a lipoprotein pathway: Implications for cerebral amyloid angiopathy
-
Urmoneit B, Prikulis I, Wihl G, D'Urso D, Frank R, Heeren J, Beisiegel U, Prior R. 1997. Cerebrovascular smooth muscle cells internalize Alzheimer amyloid beta protein via a lipoprotein pathway: implications for cerebral amyloid angiopathy. Lab Invest 77:157-166.
-
(1997)
Lab Invest
, vol.77
, pp. 157-166
-
-
Urmoneit, B.1
Prikulis, I.2
Wihl, G.3
D'Urso, D.4
Frank, R.5
Heeren, J.6
Beisiegel, U.7
Prior, R.8
-
100
-
-
0032837741
-
The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging
-
Wang J, Dickson DW, Trojanowski JQ, Lee VM. 1999. The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging. Exp Neurol 158:328-337.
-
(1999)
Exp Neurol
, vol.158
, pp. 328-337
-
-
Wang, J.1
Dickson, D.W.2
Trojanowski, J.Q.3
Lee, V.M.4
-
101
-
-
0029844205
-
Human apolipoprotein E: The Alzheimer's disease connection
-
Weisgraber KH, Mahley RW. 1996. Human apolipoprotein E: the Alzheimer's disease connection. FASEB J 10:1485-1494.
-
(1996)
FASEB J
, vol.10
, pp. 1485-1494
-
-
Weisgraber, K.H.1
Mahley, R.W.2
-
102
-
-
0027970307
-
Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro
-
Wisniewski T, Castaño EM, Golabek A, Vogel T, Frangione B. 1994. Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am J Pathol 145:1030-1035.
-
(1994)
Am J Pathol
, vol.145
, pp. 1030-1035
-
-
Wisniewski, T.1
Castaño, E.M.2
Golabek, A.3
Vogel, T.4
Frangione, B.5
-
103
-
-
0027255422
-
Apolipoprotein E: Binding to soluble Alzheimer's β-amyloid
-
Wisniewski T, Golabek A, Matsubara E, Ghiso J, Frangione B. 1993. Apolipoprotein E: binding to soluble Alzheimer's β-amyloid. Biochem Biophys Res Commun 192:359-365.
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 359-365
-
-
Wisniewski, T.1
Golabek, A.2
Matsubara, E.3
Ghiso, J.4
Frangione, B.5
-
104
-
-
0029836629
-
Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E
-
Wood SJ, Chan W, Wetzel R. 1996. Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E. Biochemistry 35:12623-12628.
-
(1996)
Biochemistry
, vol.35
, pp. 12623-12628
-
-
Wood, S.J.1
Chan, W.2
Wetzel, R.3
-
105
-
-
0031848185
-
Scavenger receptor family proteins: Roles for atherosclerosis, host defence and disorders of the central nervous system
-
Yamada Y, Doi T, Hamakubo T, Kodama T. 1998. Scavenger receptor family proteins: roles for atherosclerosis, host defence and disorders of the central nervous system. Cell Mol Life Sci 54:628-640.
-
(1998)
Cell Mol Life Sci
, vol.54
, pp. 628-640
-
-
Yamada, Y.1
Doi, T.2
Hamakubo, T.3
Kodama, T.4
-
106
-
-
0013615899
-
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
-
Yan SD, Chen X, Fu J, Chen M, Zu H, Roher A, Slattery T, Zhao L, Nagashima M, Morser J, Migheli A, Nawroth P, Stern D, Schmidt AM. 1996. RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease. Nature 382:685-691.
-
(1996)
Nature
, vol.382
, pp. 685-691
-
-
Yan, S.D.1
Chen, X.2
Fu, J.3
Chen, M.4
Zu, H.5
Roher, A.6
Slattery, T.7
Zhao, L.8
Nagashima, M.9
Morser, J.10
Migheli, A.11
Nawroth, P.12
Stern, D.13
Schmidt, A.M.14
-
107
-
-
0032526652
-
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Aβ1-42 pathogenesis
-
Yang AJ, Chandswangbhuvana D, Margol L, Glabe CG. 1998. Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Aβ1-42 pathogenesis. J Neurosci Res 52:691-698.
-
(1998)
J Neurosci Res
, vol.52
, pp. 691-698
-
-
Yang, A.J.1
Chandswangbhuvana, D.2
Margol, L.3
Glabe, C.G.4
-
108
-
-
0031013110
-
Characterization of the binding of amyloid β peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma
-
Yang DS, Smith JD, Zhou Z, Gandy SE, Martins RN. 1997. Characterization of the binding of amyloid β peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma. J Neurochem 68:721-725.
-
(1997)
J Neurochem
, vol.68
, pp. 721-725
-
-
Yang, D.S.1
Smith, J.D.2
Zhou, Z.3
Gandy, S.E.4
Martins, R.N.5
-
110
-
-
0029754637
-
Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E
-
Zhou Z, Smith JD, Greengard P, Gandy S. 1996. Alzheimer amyloid-beta peptide forms denaturant-resistant complex with type epsilon 3 but not type epsilon 4 isoform of native apolipoprotein E. Mol Med 2:175-180.
-
(1996)
Mol Med
, vol.2
, pp. 175-180
-
-
Zhou, Z.1
Smith, J.D.2
Greengard, P.3
Gandy, S.4
-
111
-
-
0028610508
-
Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta
-
Zlokovic BV, Martel CL, Mackic JB, Matsubara E, Wisniewski T, McComb JG, Frangione B, Ghiso J. 1994. Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta. Biochem Biophys Res Commun 205:1431-1437.
-
(1994)
Biochem Biophys Res Commun
, vol.205
, pp. 1431-1437
-
-
Zlokovic, B.V.1
Martel, C.L.2
Mackic, J.B.3
Matsubara, E.4
Wisniewski, T.5
McComb, J.G.6
Frangione, B.7
Ghiso, J.8
|