Lack of a significant role for the PerR regulator in Bacillus subtilis spore resistance

FEMS Microbiology Letters

Volumn 188, Issue 2, 2000, Pages 203-208

  Casillas Martinez, Lilliam ^a   Driks, Adam ^b   Setlow, Barbara ^a   Setlow, Peter ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

Alkyl hydroperoxide reductase; Bacillus subtilis; Catalase; Oxidative stress; Spore resistance

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; OXIDOREDUCTASE; PROTEIN; TERT BUTYL HYDROPEROXIDE;

ARTICLE; BACILLUS SUBTILIS; BACTERIAL SPORE; CONTROLLED STUDY; GERMINATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN ANALYSIS; REGULATOR GENE; REPRESSOR GENE;

BACILLUS SUBTILIS; BACTERIAL PROTEINS; CATALASE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HEAT; HYDROGEN PEROXIDE; MUTATION; OXIDATIVE STRESS; PEROXIDASES; REPRESSOR PROTEINS; SPORES, BACTERIAL; TERT-BUTYLHYDROPEROXIDE; TIME FACTORS; TRANSCRIPTION FACTORS;

BACILLUS SUBTILIS;

EID: 0034662489     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(00)00236-6     Document Type: Article

References (21)

1. Demple B. Regulation of bacterial oxidative stress genes. Annu. Rev. Genet. 25:1991;315-337.
2. Farr S.B., Kogoma T. Oxidative stress responses in Escherichia coli and Salmonella typhimurium. Microbiol. Rev. 55:1991;561-585.
3. Loewen P.C., Switala J. Multiple catalases in Bacillus subtilis. J. Bacteriol. 169:1987;3601-3607.
4. Antelmann H., Engelmann S., Schmid R., Hecker M. General and oxidative stress responses in Bacillus subtilis: cloning, expression, and mutation of the alkyl hydroperoxide reductase operon. J. Bacteriol. 178:1996;6571-6578.
5. Bsat N., Chen L., Helmann J.D. Mutation of the Bacillus subtilis alkyl hydroperoxide reductase (ahpCF) operon reveals compensatory interactions among hydrogen peroxide stress genes. J. Bacteriol. 178:1996;6579-6586.
6. Casillas-Martinez L., Setlow P. Alkyl hydroperoxide reductase, catalase, MrgA, and superoxide dismutase are not involved in resistance of Bacillus subtilis spores to heat or oxidizing agents. J. Bacteriol. 179:1997;7420-7425.
7. Chen L., Helmann J.D. Bacillus subtilis MrgA is a Dps (PexB) homologue: evidence for metalloregulation of an oxidative stress gene. Mol. Microbiol. 18:1995;295-300.
8. Bsat N., Herbig A., Casillas-Martinez L., Setlow P., Helmann J.D. Bacillus subtilis contains multiple Fur homologs: identification of the iron uptake (Fur) and peroxide regulon (Per) repressors. Mol. Microbiol. 29:1998;189-198.
9. Chen L., Keramati L., Helmann J.D. Coordinate regulation of Bacillus subtilis peroxide stress genes by hydrogen peroxide and metal ions. Proc. Natl. Acad. Sci. USA. 92:1995;8190-8194.
10. Marquis R.E., Sim J., Shin S.Y. Molecular mechanisms of resistance to heat and oxidative damage. J. Appl. Bacteriol. 76:1994;40S-48S.
11. Setlow P. Mechanisms which contribute to the long-term survival of spores of Bacillus species. J. Appl. Bacteriol. 76:1994;49S-60S.
12. Setlow P. Mechanisms for the prevention of damage to the DNA in spores of Bacillus species. Annu. Rev. Microbiol. 49:1995;29-54.
13. F, and KatX is essential for hydrogen peroxide resistance of the germinating and outgrowing spore. J. Bacteriol. 180:1998;2057-2062.
14. Mason J.M., Setlow P. Evidence for an essential role for small, acid-soluble, spore proteins in the resistance of Bacillus subtilis spores to ultraviolet light. J. Bacteriol. 167:1986;174-178.
15. Nicholson, W.L. and Setlow, P. (1990) Sporulation, germination and outgrowth. In: Molecular Biological Methods for Bacillus (Harwood, C.R. and Cutting, S.M., Eds.), pp. 391-450. John Wiley and Sons, Chichester.
16. Bauer T., Little S., Stover A., Driks A. Functional regions of the B. subtilis spore coat morphogenetic protein CotE distinct regions involved in localization and assembly. J. Bacteriol. 181:1999;7065-7069.
17. Rotman Y., Fields M.L. A modified reagent for dipicolinic acid analyses. Anal. Biochem. 22:1967;168.
18. Gonzalez-Flecha B., Demple B. Homeostatic regulation of intracellular hydrogen peroxide concentration in aerobically growing Escherichia coli. J. Bacteriol. 179:1997;382-388.
19. Henriques A.O., Melsen L.R., Moran C.P. Jr. Involvement of superoxide dismutase in spore coat assembly in Bacillus subtilis. J. Bacteriol. 180:1998;2285-2291.
20. Russell A.D. Bacterial spores and chemical sporicidal agents. Clin. Micobiol. Rev. 3:1990;99-119.
21. Setlow B., Setlow P. Levels of oxidized and reduced pyridine nucleotides in dormant spores and during growth, sporulation and spore germination of Bacillus megaterium. J. Bacteriol. 129:1977;857-865.