Hippocampal γ-aminobutyric acid transporter alterations following focal epileptogenesis induced in rat amygdala

Brain Research Bulletin

Volumn 52, Issue 5, 2000, Pages 357-361

  Ueda, Yuto ^a   Willmore, L James ^b  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Epilepsy; FeCl3; GABA; GABA transporters; Western blot

Indexed keywords

CARRIER PROTEIN; FERRIC CHLORIDE;

AMYGDALOID NUCLEUS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FOCAL EPILEPSY; GABAERGIC TRANSMISSION; HIPPOCAMPUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN VARIANT; RAT;

AMYGDALA; ANIMALS; CARRIER PROTEINS; CHRONIC DISEASE; EPILEPSIES, PARTIAL; FERRIC COMPOUNDS; FUNCTIONAL LATERALITY; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; HIPPOCAMPUS; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; MICROINJECTIONS; ORGANIC ANION TRANSPORTERS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034662017     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(00)00272-0     Document Type: Article

References (35)

1. Akbar M.T., Rattray M., Williams R.J., Chong N.W.S., Meldrum B.S. Reduction of GABA and glutamate transporter messenger RNAs in the severe-seizure genetically epilepsy-prone rat. Neuroscience. 85:1998;1235-1251.
2. Amara S.G., Kuhar M.J. Neurotransmitter transporters Recent progress . Annu. Rev. Neurosci. 16:1993;73-93.
3. Atwell D., Barbour B., Szathowski M. Nonvesicular release of neurotransmitter. Neuron. 11:1993;401-407.
4. Babb T.L., Pretorius J.K., Kupfer W.R., Crandall P.H. Glutamate decarboxylase-immunoreactive neurons are preserved in human epileptic hippocampus. J. Neurosci. 9:1989;2562-2574.
5. Borden L.A., Smith K.E., Hartig P.R., Branchek T.A., Weinshank R.L. Molecular heterogeneity of gamma-aminobutyric acid (GABA) transport system. J. Biol. Chem. 267:1992;21098-21104.
6. Borden L.A., Smith K.E., Vaysse P.J.J., Gustafson E.L., Weinshank R.L., Branchek T.A. Re-evaluation of GABA transport in neuronal and glial cell cultures Correlation of pharmacology and mRNA localization . Receptor Channels. 3:1995;129-146.
7. Clark J.A., Deutch A.Y., Gallipoli P.Z., Amara S.G. Functional expression and CNS distribution of a beta-alanine-sensitive neuronal GABA transporter. Neuron. 9:1992;337-348.
8. +] coupled L-glutamate transporter purified from rat brain is localized to glial cell processes. Neuroscience. 51:1992;295-310.
9. During M.J., Ryder K.M., Spencer D.D. Hippocampal GABA transporter function in temporal-lobe epilepsy. Nature. 376:1995;174-177.
10. Durkin M.M., Smith K.E., Borden L.A., Weinshank R.L., Branchek T.A., Gustafson E.L. Localization of messenger RNAs encoding three GABA transporters in rat brain An in situ hybridization study . Mol. Brain Res. 33:1995;7-21.
11. Gean P.W., Shinnick-Gallagher S., Anderson A.C. Spontaneous epileptiform activity and alteration of GABA- and of NMDA-mediated neurotransmission in amygdala neurons kindled in vivo. Brain Res. 494:1989;177-181.
12. Guastella J., Nelson N., Nelson H. Cloning and expression of a rat brain GABA transporter. Science. 249:1990;1303-1306.
13. 3H] GABA from hippocampal neurons in primary culture. Brain Res. 482:1989;23-33.
14. Hirao T., Mirimoto K., Yamamoto Y., Watanabe T., Sato H., Sato K., Sato S., Yamada N., Tanaka K., Suwaki H. Time-dependent and regional expression of GABA transporter mRNAs following amygdala-kindled seizures in rats. Mol. Brain Res. 54:1998;49-55.
15. Hironishi M., Ueyama E., Senba E. Systematic expression of immediate early genes and intensive astrocyte activation induced by intrastriatal ferrous iron injection. Brain Res. 828:1999;145-153.
16. Iverson L.L., Kelly J.S. Uptake and metabolism of gamma-aminobutyric acid by neurons and glial cells. Biochem. Pharmacol. 24:1975;933-938.
17. Kamphuis W., Lopes da Silva F.H., Wadman W.J. Changes in local evoked potentials in the rat hippocampus during kindling epileptogenesis. Brain Res. 440:1988;205-215.
18. Kapur J., Michaelson H.B., Buterbaugh G.G., Lothman E.W. Evidence for a chronic loss of inhibition in the hippocampus after kindling Electrophysiological studies . Epilepsy Res. 4:1989;90-99.
19. King G.L., Dingledine R., Giacchino J.L., McNamara J.O. Abnormal neuronal excitability in hippocampal slices from kindled rats. J. Neurophysiol. 54:1985;1295-1304.
20. Kubova H., Haugvicova R., Mares P. Effects of NNC711, a GABA uptake inhibitor, on pentylenetetrazol-induced seizures in developing and adult rats. Naunyn Schmiedebergs Arch. Pharmacol. 358:1998;334-341.
21. Levi G., Raiteri M. Carrier-mediated release of neurotransmitters. Trends Neurosci. 16:1993;415-418.
22. Lopez-Corcuera B., Liu Q.R., Mandiyan S., Nelson H., Nelson N. Expression of a mouse brain cDNA encoding novel gamma-aminobutyric acid transporter. J. Biol. Chem. 267:1992;17491-17493.
23. Masukawa L.M., Higashima M., Kim J.H., Spencer D.D. Epileptiform discharges evoked in hippocampal brain slices from epileptic patients. Brain Res. 493:1989;168-174.
24. Mathern G.W., Mendoza D., Lozada A., Pretorius J.K., Dehnes Y., Danbolt N.C., Nelson N., Leite J.P., Chimelli L., Born D.E., Sakamoto A.C., Assirati J.A., Fried I., Peacock W.J., Ojemann G.A., Adelson P.D. Hippocampal GABA and glutamate transporter immunoreactivity in patients with temporal lobe epilepsy. Neurology. 52:1999;453-472.
25. Minelli A., Brecha N.C., Karschin C., DeBiasi S., Conti F. GAT-1, a high affinity GABA plasma membrane transporter is localized to neurons and astroglia in the cerebral cortex. J. Neurosci. 15:1995;7734-7746.
26. Morimoto K., Hoimes K.H., Goddard G.V. Kindling induced changes in EEG recorded during stimulation from the site of stimulation III. Direct pharmacological manipulations of the kindled amygdala . Exp. Neurol. 97:1987;17-34.
27. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1986;Academic Press, San Diego, CA.
28. Ribak C.E., Tong W.M.Y., Brecha N.C. GABA plasma membrane transporters. GAT-1 and GAT-2, display different distributions in the rat hippocampus. J. Comp. Neurol. 367:1996;595-606.
29. Risso S., DeFelice L.J., Blakely R.D. Sodium-dependent GABA-induced currents in GAT1-transfected HeLa cells. J. Physiol. (Lond.). 490:1996;691-702.
30. Schagger H., Von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100kDa. Anal. Biochem. 166:1987;368-379.
31. Towbin H., Stahelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets Procedure and some applications . Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
32. 3 causes spontaneous recurrent seizures. Exp. Neurol. 153:1998;123-127.
33. Ueda Y., Tsuru N. Simultaneous monitoring of the seizure-related changes in extracellular glutamate and gamma aminobutyric acid concentration in bilateral hippocampi following development of amygdaloid kindling. Epilepsy Res. 20:1995;213-219.
34. Yamada N., Bilkey D.K. Kindling-induced persistent alterations in the membrane and synaptic properties of CA1 pyramidal neurons. Brain Res. 561:1991;324-331.
35. Yan X.X., Ribak C.E. Alteration of GABA transporter expression in the rat cerebral cortex following needle puncture and colchicine injection. Brain Res. 816:1999;317-328.