Noncompetitive, reversible inhibition of aminoacylase-1 by a series of L-α-hydroxyl and L-α-fluoro fatty acids: Ligand specificity of Aspergillus oryzae and porcine kidney enzymes

Archives of Biochemistry and Biophysics

Volumn 379, Issue 2, 2000, Pages 261-266

  Tamura, Takashi ^a   Oki, Yoshiko ^a   Yoshida, Atsuhito ^a   Kuriyama, Takatoshi ^a   Kawakami, Hiroshi ^a   Inoue, Hiroyuki ^a   Inagaki, Kenji ^a   Tanaka, Hidehiko ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Aminoacylase 1; L fluoro fatty acids; L hydroxyl fatty acids; Noncompetitive inhibitor

Indexed keywords

2 HYDROXYACID; ALKYL GROUP; AMIDASE; FATTY ACID DERIVATIVE; FLUORINE DERIVATIVE; FUNGAL ENZYME; HYDROXY FATTY ACID; KIDNEY ENZYME; LACTIC ACID; LACTIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE;

ARTICLE; ASPERGILLUS ORYZAE; BINDING AFFINITY; COMPETITIVE INHIBITION; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; PH; PRIORITY JOURNAL; STEREOCHEMISTRY; STREPTOMYCES; SWINE;

EID: 0034661399     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.2000.1869     Document Type: Article

References (18)

1. Greenstein J. P. Methods Enzymol. 3:1957;554-570.
2. Birnbaum S. M., Levintow L., Kingsley R. B., Greenstein J. P. J. Biol. Chem. 194:1952;455-470.
3. Gentzen I., Loffler H.-G., Schneider F. Z. Naturforsch. Teil C. 35:1980;544-550.
4. Sakanyan V., Desmarez L., Legrain C., Charlier D., Mett I., Kochikyan A., Savchenko A., Boyen A., Falmagne P., Pierard A., Glansdorff N. Appl. Environ. Microbiol. 59:1993;3878-3888.
5. Lugay J. C., Aronson J. N. Biochim. Biophys. Acta. 191:1969;397-414.
6. Gade W., Brown J. L. Biochim. Biophys. Acta. 662:1981;86-93.
7. Heese D., Loffler H. G., Rohm K.-H. Biol. Chem. Hoppe-Seyler. 369:1988;559-566.
8. Olah G. A., Prakash G. K., Chao Y. L. Helv. Chim. Acta. 662:1981;86-93.
9. Britton H. T. S., Robinson R. A. J. Chem. Soc. 1931;1456-1462.
10. Cleland W. W. Enzymes. 2:1970;1-65.
11. Kubinyi H. QSAR: Hansch Analysis and Related Approaches. 1993;VCH Publishers, New York. p. 21-27.
12. Kördel W., Schneider F. Z. Naturforschung. 32:1977;342-344.
13. Gilles I., Löffler H. G., Schneider F. Z. Naturforschung. 36:1981;751-754.
14. Wang Z. W., Wu H. B., Wang X. C., Zhou H. M., Tsou C. L. Biochem. J. 281:1992;285-290.
15. Wu H. B., Tsou C. L. Biochem. J. 296:1992;435-441.
16. Heese D., Berger S., Rohm K. H. Eur. J. Biochem. 188:1990;175-180.
17. Lugay J. C., Aronson J. N. Biochim. Biophys. Acta. 191:1969;397-414.
18. Galaev I. Y., Svedas V. K. Biochim. Biophys. Acta. 701:1982;389-394.