The imbalanced brain: From normal behavior to schizophrenia

Biological Psychiatry

Volumn 48, Issue 2, 2000, Pages 81-98

  Grossberg, Stephen ^a  

^a BOSTON UNIVERSITY   (United States)

Author keywords

Amygdala; Arousal; Neural networks; Opponent process; Prefrontal cortex; Schizophrenia

Indexed keywords

AMYGDALOID NUCLEUS; AROUSAL; ARTIFICIAL NEURAL NETWORK; BEHAVIOR; COGNITION; EMOTION; LEARNING; MOTIVATION; NEUROTRANSMISSION; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; SENSORY CORTEX;

AFFECT; AMYGDALA; AROUSAL; ASSOCIATION LEARNING; ATTENTION; BEHAVIOR; COGNITION DISORDERS; CONDITIONING, CLASSICAL; HABITUATION, PSYCHOPHYSIOLOGIC; HUMANS; MOTIVATION; NERVE NET; NEUROPSYCHOLOGICAL TESTS; PREFRONTAL CORTEX; SCHIZOPHRENIA;

EID: 0034661159     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(00)00903-3     Document Type: Review

References (135)

1. Abbott L.F., Varela K., Sen K., Nelson S.B. Synaptic depression and cortical gain control. Science. 275:1997;220-223.
2. Aggleton J.P. The contribution of the amygdala to normal and abnormal emotional states. Trends Neurosci. 16:1993;328-333.
3. Amaral D.C., Price J.L. Amygdalo-cortical projections in the monkey (Macaca fascicularis). J Comp Neurol. 230:1984;465-496.
4. Andreasen N.C. Positive and negative symptoms Historical and conceptual aspects . Mod Probl Pharmacopsychiatry. 24:1990;1.
5. Arndt S., Alliger R.J., Andreasen N.C. The distinction of positive and negative symptoms The failure of a two-dimensional model . Br J Psychiatry. 158:1991;317-322.
6. Aston-Jones G., Rajkowski J., Kubiak P., Alexinsky T. Locus coeruleous neurons in monkey are selectively activated by attended cues in a vigilance task. J Neurosci. 14:1994;4467-4480.
7. Baddeley A.D. Working Memory. 1986;Clarendon, Oxford, UK.
8. Baloch A., Grossberg S., Mingolla E., Nogueira C.A.M. Neural model of first-order and second-order motion perception and magnocellular dynamics. J Opt Soc Am A. 16:1999;953-978.
9. Barbas H. Anatomic basis of cognitive-emotional interactions in the primate prefrontal cortex. Neurosci Biobehav Rev. 19:1995;499-510.
10. Bleuler E (1950): Dementia Praecox, or the Group of Schizophrenics [Zinken J, translator]. New York: International Universities Press [original work published 1911].
11. Blumer D., Benson D.F. Personality changes with frontal lobe lesions. Benson D.F., Blumer D. Psychiatric Aspects of Neurological Disease. 1975;151-170 Grune and Stratton, New York.
12. Bower G.H. Mood and memory. Am Psychol. 36:1981;129-148.
13. Bradski G., Carpenter G.A., Grossberg S. STORE working memory networks for storage and recall of arbitrary temporal sequences. Biol Cybern. 71:1994;469-480.
14. Braff D.L. Attention, habituation, and information processing in psychiatric disorders. Michael B., Cavenar J.O., Brodie H.K., et al. Psychiatry. Vol 3:1985;1-12 Lippincott, Philadelphia.
15. Brown J.L. Afterimages. Graham C.H. Vision and Visual Perception. 1965;479-503 Wiley, New York.
16. Buchanan R.W., Strauss M.E., Breier A., Kirkpatrick B., Carpenter W.T. Attentional impairments in deficit and nondeficit forms of schizophrenia. Am J Psychiatry. 154:1997;363-370.
17. Bullock D., Cisek P., Grossberg S. Cortical networks for control of voluntary arm movements under variable force conditions. Cereb Cortex. 8:1998;48-62.
18. Buonomano D.V., Baxter D.A., Byrne J.H. Small networks of empirically derived adaptive elements simulate some higher-order features of classical conditioning. Neural Networks. 3:1990;507-523.
19. Bustillo J.R., Thaker G., Buchanan R.W., Moran M., Kirkpatrick B., Carpenter W.T. Visual information-processing impairments in deficit and nondeficit schizophrenia. Am J Psychiatry. 154:1997;647-654.
20. Carlsson A. The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacology. 1:1988;179.
21. Carpenter G.A., Grossberg S. Adaptation and transmitter gating in vertebrate photoreceptors. J Theor Neurobiol. 1:1981;1-42.
22. Carpenter G.A., Grossberg S. A neural theory of circadian rhythms The gated pacemaker . Biol Cybern. 48:1983;35-59.
23. Carpenter G.A., Grossberg S. A neural theory of circadian rhythms Aschoff's rule in diurnal and nocturnal mammals . Am J Physiol. 247:1984;R1067-R1082.
24. Carpenter G.A., Grossberg S. A neural theory of circadian rhythms Split rhythms, after-effects, and motivational interactions . J Theor Biol. 113:1985;163-223.
25. Carpenter G.A., Grossberg S. Integrating symbolic and neural processing in a self-organizing architecture for pattern recognition and prediction. Honavar V., Uhr L. Artificial Intelligence and Neural Networks Steps Towards Principled Prediction . 1994;387-421 Academic Press, San Diego.
26. Contreras-Vidal J.L., Grossberg S., Bullock D. A neural model of cerebellar learning for arm movement control Cortico-spinal-cerebellar dynamics . Learning Memory. 3:1997;475-502.
27. Cox V.C., Kakolewski J.W., Valenstein E.S. Inhibition of eating and drinking following hypothalamic stimulation in the rat. J Comp Physiol Psychol. 68:1969;530-535.
28. Damasio A.R. The Feeling of What Happens. 1999;Harcourt Brace, New York.
29. Damasio A.R., Tranel D., Damasio H. Somatic markers and the guidance of behavior Theory and preliminary testing . Levin H.S., Eisenberg H.M., Benton A.L. Frontal Lobe Function and Dysfunction. 1991;217-229 Oxford University Press, Oxford, UK.
30. Davis M. The role of the amygdala in emotional learning. Int Rev Neurobiol. 36:1994;225-265.
31. Denny M.R. Relaxation theory and experiments. Brush F.R. Aversive Conditioning and Learning. 1971;235-295 Academic Press, New York.
32. Desimone R. Face-selective cells in the temporal cortex of monkeys. J Cogn Neurosci. 3:1991;1-8.
33. Dews P.B. Studies on behavior, IV Stimulant actions of methamphetamine . J Pharmacol Exp Ther. 122:1958;137-147.
34. Early T.S., Haller J.W., Posner M.I., Raichle M. The left striato-pallidal hyperactivity model of schizophrenia. David A.S., Cutting J.C. The Neuropsychology of Schizophrenia. 1994;15-37 Erlbaum, Hillsdale, NJ.
35. Estes W.K., Skinner B.F. Some quantitative properties of anxiety. J Exp Psychol. 29:1941;390-400.
36. Evarts E.V. Motor cortex reflexes associated with learned movement. Science. 179:1973;501-503.
37. Felleman D.J., van Essen C.D. Distributed hierarchical processing in the primate cerebral cortex. Cereb Cortex. 1:1991;1-47.
38. Fiala J.C., Grossberg S., Bullock D. Metabotropic glutamate receptor activation in cerebellar Purkinje cells as substrate for adaptive timing of classically conditioned eye blink response. J Neurosci. 16:1996;3760-3774.
39. Francis G., Grossberg S. Cortical dynamics of boundary segmentation and reset Persistence, afterimages, and residual traces . Perception. 25:1996;543-567.
40. Francis G., Grossberg S. Cortical dynamics of form and motion integration Persistence, apparent motion, and illusory contours . Vision Res. 36:1996;149-173.
41. Francis G., Grossberg S., Mingolla E. Cortical dynamics of feature binding and reset Control of visual persistence . Vision Res. 34:1994;1089-1104.
42. Frith C.D. The Cognitive Neuropsychology of Schizophrenia. 1992;Erlbaum, Hillsdale, NJ.
43. Frith C.D. Theory of mind in schizophrenia. David A.S., Cutting J.C. The Neuropsychology of Schizophrenia. 1994;147-161 Erlbaum, Hillsdale, NJ.
44. Fulton J.F. Frontal Lobotomy and Affective Behavior. 1950;Norton, New York.
45. Fuster J.M. The Prefrontal Cortex. 2nd ed. 1989;Raven, New York.
46. Gloor P., Olivier A., Quesney L.F., Andermann F., Horowitz S. The role of the limbic system in experiential phenomena of temporal lobe epilepsy. Ann Neurol. 12:1982;129-144.
47. Gochin P.M., Miller E.K., Gross C.G., Gerstein G.L. Functional interactions among neurons in inferior temporal cortex of the awake macaque. Exp Brain Res. 84:1991;505-516.
48. Grace A.A. Phasic versus tonic dopamine release and the modulation of dopamine system responsivity A hypothesis for the etiology of schizophrenia . Neuroscience. 41:1991;1-24.
49. Grossberg S. Some physiological and biochemical consequences of psychological postulates. Proc Natl Acad Sci U S A. 60:1968;758-765.
50. Grossberg S. On the production and release of chemical transmitters and related topics in cellular control. J Theor Biol. 22:1969;325-364.
51. Grossberg S. On the dynamics of operant conditioning. J Theor Biol. 33:1971;225-255.
52. Grossberg S. A neural theory of punishment and avoidance, I Qualitative theory . Math Biosci. 15:1972;39-67.
53. Grossberg S. A neural theory of punishment and avoidance, II Quantitative theory . Math Biosci. 15:1972;253-285.
54. Grossberg S. Contour enhancement, short term memory, and constancies in reverberating neural networks. Stud Appl Math. 52:1973;217-257.
55. Grossberg S. A neural model of attention, reinforcement, and discrimination learning. Int Rev Neurobiol. 18:1975;263-327.
56. Grossberg S. Behavioral contrast in short term memory Serial binary memory models or parallel continuous memory models? J Math Psychol. 3:1978;199-219.
57. Grossberg S. A theory of human memory Self-Organization and performance of sensory-motor codes, maps, and plans . Rosen R., Snell F. Progress in Theoretical Biology. 1978;233-374 Academic Press, New York.
58. Grossberg S. How does a brain build a cognitive code? Psychol Rev. 1:1980;1-51.
59. Grossberg S. Associative and competitive principles of learning and development The temporal unfolding and stability of STM and LTM patterns . Amari S.I., Arbib M. Competition and Cooperation in Neural Networks. 1982;295-341 Springer-Verlag, New York.
60. Grossberg S. Processing of expected and unexpected events during conditioning and attention A psychophysiological theory . Psychol Rev. 89:1982;529-572.
61. Grossberg S. Some normal and abnormal behavioral syndromes due to transmitter gating of opponent processes. Biol Psychiatry. 19:1984;1075-1118.
62. Grossberg S. Some psychophysiological and pharmacological correlates of a developmental, cognitive, and motivational theory. Karrer R., Cohen J., Tueting P. Brain and Information Event Related Potentials . 1984;58-142 New York Academy of Sciences, New York.
63. Grossberg S. The Adaptive Brain. Vol I:1987;Elsevier/North-Holland, Amsterdam.
64. Grossberg S. Cortical dynamics of three-dimensional form, color, and brightness perception, II Binocular theory . Perception Psychophys. 41:1987;117-158.
65. Grossberg S. The link between brain learning, attention, and consciousness. Conscious Cogn. 8:1999;1-44.
66. Grossberg S (in press): How hallucinations may arise from brain mechanisms of learning, attention, and volition. J Int Neuropsychol Soc.
67. Grossberg S., Gutowski S. Neural dynamics of decision making under risk Affective balance and cognitive-emotional interactions . Psychol Rev. 94:1987;300-318.
68. Grossberg S., Levine D.S. Neural dynamics of attentionally modulated Pavlovian conditioning Blocking, inter-stimulus interval, and secondary conditioning . Appl Opt. 26:1987;5015-5030.
69. Grossberg S., Merrill J.W.L. A neural network model of adaptively timed reinforcement learning and hippocampal dynamics. Cogn Brain Res. 1:1992;3-38.
70. Grossberg S., Merrill J.W.L. The hippocampus and cerebellum in adaptively timed learning, recognition, and movement. J Cogn Neurosci. 8:1996;257-277.
71. Grossberg S., Schmajuk N.A. Neural dynamics of attentionally-modulated Pavlovian conditioning Conditioned reinforcement, inhibition, and opponent processing . Psychobiology. 15:1987;195-240.
72. Grossberg S., Stone G. Neural dynamics of attention switching and temporal order information in short term memory. Memory Cogn. 14:1986;451-468.
73. Halgren E., Walter R.D., Cherlow D.G., Crandall P.H. Mental phenomena evoked by electrical stimulations of the human hippocampal formation and amygdala. Brain. 101:1978;83-117.
74. Harries M.H., Perrett D.I. Visual processing of faces in temporal cortex Physiological evidence for a modular organization and possible anatomical correlates . J Cogn Neurosci. 3:1991;9-24.
75. Heinrichs R.W. Schizophrenia and the brain Conditions for a neuropsychology of madness . Am Psychol. 48:1993;221-233.
76. Horak R.B., Anderson M.E. Influence of globus pallidus on arm movements in monkeys, I Effects of nainic acid-induced lesions . J Neurophysiol. 52:1984;290-304.
77. Horak R.B., Anderson M.E. Influence of globus pallidus on arm movements in monkeys, II Effects of stimulations . J Neurophysiol. 52:1984;305-322.
78. Hornykiewicz O. Parkinsonism induced by dopaminergic antagonists. Calne D.B., Barbeau A. Advances in Neurology. Vol 9:1975;Raven, New York.
79. Ito M. The Cerebellum and Neural Control. 1984;Raven, New York.
80. Kalaska J.F., Cohen D.A.D., Hyde M.L., Prud'homme M.J. A comparison of movement direction-related versus load direction-related activity in primate motor cortex using a two-dimensional reaching task. J Neurosci. 9:1989;2080-2102.
81. Kamin L.J. "Attention-like" processes in classical conditioning. Jones M.R. Miami Symposium on the Prediction of Behavior Aversive Stimulation . 1968;9-31 University of Miami Press, Miami.
82. Kamin L.J. Predictability, surprise, attention and conditioning. Campbell B.A., Church R.M. Punishment and Aversive Behavior. 1969;279-298 Appleton-Century-Crofts, New York.
83. Kraepelin E (1919): Dementia Praecox and Paraphrenia [Barclay RM, translator]. Edinburgh: ES Livingston [original work published 1913].
84. Kuhar M.J., Atweh S.F., Bird S.J. Studies of cholinergic-monoaminergic interactions in rat brain. Butcher L.L. Cholinergic-Monoaminergic Interactions in the Brain. 1978;Academic Press, New York.
85. LeDoux J.E. Emotional memory systems in the brain. Behav Brain Res. 58:1993;69-79.
86. Leibowitz S.F. Adrenergic receptor mechanisms in eating and drinking. Schmitt F.O., Worden F.G. The Neurosciences Third Study Program. 1974;MIT Press, Cambridge, MA.
87. Liddle P.F. Volition and schizophrenia. David A.S., Cutting J.C. The Neuropsychology of Scizophrenia. 1994;39-49 Erlbaum, Hillsdale, NJ.
88. Lloyd K.G. Observations concerning neurotransmitter interaction in schizophrenia. Butcher L.L. Cholinergic-Monoaminergic Interactions in the Brain. 1978;Academic Press, New York.
89. Lynch M.E. Schizophrenia and the D1 receptor Focus on negative symptoms . Progr Neuropsychopharmacol Biol Psychiatry. 16:1992;797.
90. Macchi G, Rinvik E (1976): Thalamo-telencephalic circuits: A neuroanatomical survey. In: Rémond A, editor. Handbook of Electroencephalography and Clinical Neurophysiology, Vol 2, Part A. Amsterdam: Elsevier.
91. Markram H., Lübke J., Frotscher M., Sakmann B. Regulation of synaptic efficacy by coincidence of postsynaptic APs and EPSPs. Science. 275:1997;213-215.
92. Markram H., Tsodyks M. Redistribution of synaptic efficacy between neocortical pyramidal neurons. Nature. 382:1996;807-810.
93. Marrocco R.T., Witte E.A., Davidson M.C. Arousal systems. Curr Opin Neurobiol. 4:1994;166-170.
94. Masterson F.A. Is termination of a warning signal an effective reward for the rat? J Comp Physiol Psychol. 72:1970;471-475.
95. McAllister W.R., McAllister D.E. Behavioral measurement of conditioned fear. Brush F.R. Aversive Conditioning and Learning. 1971;105-179 Academic Press, New York.
96. McAllister W.R., McAllister D.E. The inverse relationship between shock intensity and shuttlebox avoidance learning in rats. J Comp Physiol Psychol. 74:1971;426-433.
97. Mirsky A.F. Neuropsychological bases of schizophrenia. Annu Rev Psychol. 20:1969;321-348.
98. Mishkin M., Aggleton J. Multiple functional contributions of the amygdala in the monkey. Ben-Ari Y. The Amygdaloid Complex. 1981;409-420 Elsevier, Amsterdam.
99. Netter P., Rammsayer T. Reactivity to dopaminergic drugs and aggression related personality traits. Pers Individual Differ. 12:1991;1009-1017.
100. Ögmen H. A neural theory of retino-cortical dynamics. Neural Networks. 6:1993;245-273.
101. Ögmen H., Gagné S. Neural network architectures for motion perception and elementary motion detection in the fly visual system. Neural Networks. 3:1990;487-505.
102. Pantelis C., Harvey C., Taylor J., Campbell P.G. The anterior cingulate mediates processing selection in the Stroop attentional conflict paradigm. Proc Natl Acad Sci U S A. 87:1991;256-259.
103. Passingham R.E. The Frontal Lobes and Voluntary Action. 1997;Oxford University Press, Oxford, UK.
104. Pavlov I.P. Conditioned Reflexes. 1927;Oxford University Press, London.
105. Pilowsky I., Bassett D. Schizophrenia and the response to facial emotions. Compr Psychiatry. 21:1980;515-526.
106. Rammsayer T., Netter P., Vogel W. A neurochemical model underlying differences in reaction times between introverts and extraverts. Pers Individual Differ. 14:1993;701-712.
107. Reynierse J.H., Rizley R.C. Relaxation and fear as determinants of maintained avoidance in rats. J Comp Physiol Psychol. 72:1970;223-232.
108. Reynolds G.P. Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenia. Nature. 305:1983;527-529.
109. Reynolds G.P. Post-mortem neurochemical studies in human postmortem brain tissue. Hafner H., Gattaz W.F., Janzarik W. Search for the Causes of Schizophrenia. 1987;236-240 Springer, Heidelberg, Germany.
110. Reynolds G.S. A Primer of Operant Conditioning. 1968;Scott, Foresman, Glenview, IL.
111. Riklan M. L-dopa and Parkinsonism A Psychological Assessment . 1973;C.C. Thomas, Springfield, IL.
112. Robbins T.W., Everitt B.J. Arousal systems and attention. Gazzaniga M.S. Handbook of Cognitive Neuroscience. 1995;MIT Press, Cambridge, MA.
113. Rolls E.T. The orbitofrontal cortex. Roberts A.C., Robbins T.W., Weiskrantz L. The Prefrontal Cortex Executive and Cognitive Functions . 1998;67-86 Oxford University Press, Oxford, UK.
114. Sauer H., Geider F.J., Binkert M., Reitz C., Schroder J. Is chronic schizophrenia heterogeneous? Biol Psychiatry. 29:(suppl 1):1991;661S.
115. Sekuler R. Visual motion perception. Carterette E.D., Friedman M.P. Handbook of Perception Seeing . Vol V:1975;387-433 Academic Press, San Diego.
116. Sillito A.M., Jones H.E., Gerstein G.L., West D.C. Feature-linked synchronization of the thalamic relay cell firing induced by feedback from the visual cortex. Nature. 369:1994;479-482.
117. Staddon J.E.R. Adaptive Behavior and Learning. 1983;Cambridge University Press, New York.
118. Stevens J. An anatomy of schizophrenia? Arch Gen Psychiatry. 29:1993;177-189.
119. Swanson J.M., Kinsbourne M. Stimulant-related state-dependent learning in hyperactive children. Science. 192:1976;1354-1356.
120. Tecce J.J., Cole J.O. Amphetamine effects in man Paradoxical drowsiness and lowered electrical brain activity (CNV) . Science. 185:1974;451-453.
121. Thompson R.F. The neural basis of basic associative learning of discrete behavioral responses. Trends Neurosci. 11:1988;152-155.
122. Torrey E., Peterson M. Schizophrenia and the limbic system. Lancet. II:1974;942-946.
123. Tsodyks M, Pawelzik K, Markram H (in press): Neural networks with dynamic synapses. Neural Comput.
124. Tsumoto T., Creutzfeldt O.D., Legéndy C.F. Functional organization of the corticofugal system from visual cortex to lateral geniculate nucleus in the cat. Exp Brain Res. 32:1978;345-364.
125. Turner B.H., Mishkin M., Knapp M. Organization of the amygdalopetal projections from modality-specific cortical association areas in the monkey. J Comp Neurol. 191:1980;515-643.
126. Ungerleider L.G., Mishkin M. Two cortical visual systems Separation of appearance and location of objects . Ingle D.L., Goodale M.A., Mansfield R.J.W. Analysis of Visual Behavior. 1982;549-586 MIT Press, Cambridge, MA.
127. Valenstein E.S., Cox V.C., Kakolewski J.W. The hypothalamus and motivated behavior. Tapp J.T. Reinforcement and Behavior. 1969;242-285 Academic Press, New York.
128. von Helmholtz H. Handbuch der Physiologischen Optik. 1866;Voss, Hamburg.
129. von Helmholtz H (1962): Physiological Optics, Vol 2 [Southall JP, translator]. New York: Dover.
130. Wallach M.B. Drug-induced stereotyped behavior Similarities and differences . Usdin E. Neurophyshopharmacology of Monoamines and their Regulatory Enzymes. 1974;Raven, New York.
131. Weinberger D.F. Schizophrenia and the frontal lobe. Trends Neurosci. 11:1988;367-370.
132. Weiss G., Hechtman L. The hyperactive child syndrome. Science. 205:1979;1348-1354.
133. Wilson F.A.W., Scalaidhe O., Goldman-Rakic P.S. Dissociation of object and spatial processing domains in primate prefrontal cortex. Science. 260:1993;1955-1958.
134. Wolgin D.L., Cytawa J., Teitelbaum P. The role of activation in the regulation of food intake. Novin D., Wyrwicka W., Bray G. Hunger Basic Mechanisms and Clinical Implications . 1976;Raven, New York.
135. Zuckerman M. Sensation seeking A comparative approach to a human trait . Behav Brain Sci. 7:1984;413-471.