Functional interactions between Drosophila bHLH/PAS, Sox, and POU transcription factors regulate CNS midline expression of the slit gene

Journal of Neuroscience

Volumn 20, Issue 12, 2000, Pages 4596-4605

  Ma, Yue ^a   Certel, Kaan ^b   Gao, Yanping ^a   Niemitz, Emily ^a,d   Mosher, Jack ^c   Mukherjee, Ashim ^a   Mutsuddi, Mousumi ^a   Huseinovic, Neda ^a   Crews, Stephen T ^c   Johnson, Wayne A ^b   Nambu, John R ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bHLH PAS; CNS midline; Drosophila; Gene expression; POU; slit; Sox

Indexed keywords

DNA; HELIX LOOP HELIX PROTEIN; PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; CENTRAL NERVOUS SYSTEM; DNA SEQUENCE; DROSOPHILA; EMBRYO; GENE; GENE CONTROL; GENE EXPRESSION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING;

DROSOPHILA;

EID: 0034660616     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-12-04596.2000     Document Type: Article

References (55)

1. Ambrosetti DC, Basilico C, Dailey L (1997) Synergistic activation of the fibroblast growth factor 4 enhancer by Sox2 and Oct-3 depends on protein-protein interactions facilitated by a specific spatial arrangement of factor binding sites. Mol Cell Biol 17:6321-6329.
2. Anderson MG, Perkins GL, Chittick P, Shrigley RJ, Johnson WA (1995) drifter, a Drosophila POU-domain transcription factor, is required for correct differentiation and migration of tracheal cells and midline glia. Genes Dev 9:123-137.
3. Anderson MG, Certel, Certel K, Lee T, Montell DJ, Johnson WA (1996) Function of the Drosophila POU domain transcription factor drifter as an upstream regulator of breathless receptor tyrosine kinase expression in developing trachea. Development 122:4169-4178.
4. Becker DM, Fikes JD, Guarente L (1991) A cDNA encoding a human CCAAT-binding protein cloned by functional complementation in yeast. Proc Natl Acad Sci USA 88:1968-1972.
5. Bhat KM, Poole SJ, Schedl P (1995) The miti-mere and pdm1 genes collaborate during specification of the RP2/sib lineage in Drosophila neurogenesis. Mol Cell Biol 15:4052-4063.
6. Billin AN, Cockerill KA, Poole SJ (1991) Isolation of a family of Drosophila POU domain genes expressed in early development. Mech Dev 34:75-84.
7. Botquin V, Hess H, Fuhrmann G, Anastassiadis C, Gross MK, Vriend G, Scholer HR (1998) New POU dimer conliguration mediates antagonistic control of anosteopontin preimplantation enhancer by Oct-4 and Sox-2. Genes Dev 12:2073-2090.
8. Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401-415.
9. Certel K, Anderson MG, Shrigley RJ, Johnson WA (1996) Distinct variant DNA-binding sites determine cell-specific autoregulated expression of the Drosophila POU domain transcription factor drifter in midline glia or trachea. Mol Cell Biol 16:1813-1823.
10. Crews ST (1998) Control of cell lineage-specific development and transcription bybHLH-PAS proteins. Genes Dev 12:607-620.
11. Crews ST, Fan CM (1999) Remembrance of things PAS: regulation of development by bHLH-PAS proteins. Curr Opin Genet Dev 9:580-587.
12. Fehon RG, Kooh PJ, Rebay I, Regan CL, Xu T, Muskavitch MAT, Artavanis-Tsakonas S (1990) Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell 61:523-534.
13. Gekakis N, Saez L, Delahaye-Brown AM, Myers MP, Sehgal A, Young MW, Weitz CJ (1995) Isolation of timeless by PER protein interaction: defective interaction between timeless protein and long-period mutant PERL. Science 270:811-815.
14. Guthric S (1999) Axon guidance: starting and stopping with slit. Curr Biol 9:R432-435.
15. Han K, Levine MS, Manley JL (1989) Synergistic activation and repression of transcription by Drosophila homeobox proteins. Cell 56:573-583.
16. Hardin PE (1998) Activating inhibitors and inhibiting activators: a day in the life of a by. Curr Opin Neurobiol 8:642-647.
17. Harris R, Sabatelli LM, Seeger MA (1996) Guidance cues at the Drosophila CNS midline: identification and characterization of two Drosophila Netrin/UNC-6 homologs. Neuron 17:217-228.
18. Huang ZJ, Curtin KD, Rosbash M (1995) PER protein interactions and temperature compensation of a circadian clock in Drosophila. Science 267:1169-1172.
19. Johnson WA (1992) Characterization of neuron-specific transcription factors in Drosophila melanogaster. Methods Neurosci 9:362-380.
20. Kasai Y, Stahl S, Crews ST (1998) Specification of the Drosophila CNS midline cell lineage: direct control of single-minded transcription by dorsal/ventral patterning genes. Gene Exp 7:171-189.
21. Kidd T, Bland KS, Goodman CS (1999) Slit is the midline repellent for the robo receptor in Drosophila. Cell 96:785-794.
22. Kuhlbrodt K, Herbarth B, Sock E, Enderich J, Hermans-Borgmeyer I, Wegner M (1998) Cooperative function of POU proteins and SOX proteins in glial cells. J Biol Chcm 273:16050-16057.
23. Lamb KA, Rizzino A (1998) Effects of differentiation on the transcriptional regulation of the FGF-4 gene: critical roles played by a distal enhancer. Mol Reprod Dev 51:218-224.
24. Latchman DS (1999) POU family transcription factors in the nervous system. J Cell Physiol 179:126-133.
25. Lefebvre V, Li P, de Crombrugghe BA (1998) A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene. EMBO J 17:5718-5733.
26. Ma Y, Niemitz EL, Nambu PA, Shan X, Sackerson C, Fujioka M, Goto T, Nambu JR (1998) Gene regulatory functions of Drosophila Fish-hook, a high mobility group domain Sox protein. Mech Dev 73:169-182.
27. McEvilly RJ, Rosenfeld MG (1999) The role of POU domain proteins in the regulation of mammalian pituitary and nervous system development. Prog Nucleic Acid Res Mol Biol 63:223-255.
28. Mitchell KJ, Doyle JL, Serafini T, Kennedy TE, Tessier-Lavigne M, Goodman CS, Dickson BJ (1996) Genetic analysis of Netrin genes in Drosophila: Netrins guide CNS commissural axons and peripheral motor axons. Neuron 17:203-215.
29. Mitchison TJ, Sedat J (1983) Localization of antigenic determinants in whole Drosophila embryos. Dev Biol 99:261-264.
30. Mukherjee A, Shan X, Mutsuddi M, Ma Y, Nambu JR (2000) The Drosophila Sox gene, fish-hook, is required for postembryonic development. Dev Biol 217:91-106.
31. Muralidhar MG, Callahan CA, Thomas JB (1993) Single-minded regulation of genes in the embryonic midline of the Drosophila central nervous system. Mech Dev 41:129-138.
32. Nambu JR, Lewis JO, Wharton Jr KA, Crews ST (1991) The Drosophila single-minded gene encodes a helix-loop-helix protein which acts as a master regulator of CNS midline development. Cell 67:1157-1167.
33. Nambu PA, Nambu JR (1996) The Drosophila Fish-hook gene encodes a HMG domain protein essential for segmentation and CNS development. Development 122:3467-3475.
34. Ohshiro T, Saigo K (1997) Transcriptional regulation of breathless FGF receptor gene by binding of TRACHEALESS/dARNT heterodimers to three central midline elements in Drosophila developing trachea. Development 124:3975-3986.
35. Patel NH (1994) Imaging neuronal subsets and other cell types in whole-mount Drosophila embryos and larvae using antibody probes. In: Drosophila melanogaster: practical uses in cell and molecular biology, methods in cell biology, Vol 44 (Goldstein LSB, Fyrberg EA, eds), pp 446-485. New York: Academic.
36. Pevny LH, Lovell-Badge R (1997) Sox genes find their feet. Curr Opin Genet Dev 7:338-344.
37. Rothberg JM, Hartley DA, Walther Z, Artavanis-Tsakonas S (1988) slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system. Cell 55:1047-1059.
38. Rothberg JM, Jacobs JR, Goodman CS, Artavanis-Tsakonas S (1990) slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains. Genes Dev 4:2169-2187.
39. Russell SR, Sánchez-Soriano N, Wright CR, Ashburner M (1996) The Dichaete gene of Drosophila melanogaster encodes a Sox-domain protein required for embryonic segmentation. Development 122:3669-3676.
40. Sánchez Soriano N, Russell R (1998) The Drosophila SOX-domain protein Dichaete is required for the development of the central nervous system midline. Development 125:3989-3996.
41. Sonnenfeld M, Ward M, Nystrom G, Mosher J, Stahl S, Crews ST (1997) The Drosophila tango gene encodes a bHLH-PAS protein that is orthologous to mammalian Arnt and controls CNS midline and tracheal development. Development 124:4571-4582.
42. Tear G, Harris R, Sutaria S, Kilomanski K, Goodman CS, Seeger MA (1996) commissureless controls growth cone guidance across the CNS midline in Drosophila and encodes a novel membrane protein. Neuron 16:501-514.
43. Van Vactor D, Flanagan JG (1999) The middle and the end: slit brings guidance and branching together in axon pathway selection. Neuron 22:649-652.
44. Ward MP, Mosher JT, Crews ST (1998) Regulation of bHLH-PAS protein subcellular localization during Drosophila embryogenesis. Development 125:1599-1608.
45. Wegner M (1999) From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 27:1409-1420.
46. Werner MH, Huth JR, Gronenborn AM, Clore GM (1995) Molecular basis of human 46X,Y sex reversal revealed from the three-dimensional solution structure of the human SRY-DNA complex. Cell 81:705-714.
47. Wharton Jr KA, Crews ST (1993) CNS midline enhancers of the Drosophila slit and Toll genes. Mech Dev 40:141-154.
48. Wharton Jr KA, Franks RG, Kasai Y, Crews ST (1994) Control of CNS midline transcription by asymmetric E-box-like elements: similarity to xenobiotic responsive regulation. Development 120:3563-3569.
49. Wilk R, Weizman I, Shilo BZ (1996) trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila. Genes Dev 10:93-102.
50. Xiao H, Hrdlicka L, Nambu JR (1996) Alternate functions of the single-minded and rhomboid genes in development of the Drosophila ventral neuroectoderm. Mech Dev 58:65-74.
51. Yeo SL, Lloyd A, Kozak K, Dinh A, Dick T, Yang X, Sakonju S, Chia W (1995) On the functional overlap between two Drosophila POU homeo domain genes and the cell fate specification of a CNS neural precursor. Genes Dev 9:1223-1236.
52. Young MW (1998) The molecular control of circadian behavioral rhythms and their entrainment in Drosophila. Annu Rev Biochem 67:135-152.
53. Yuan H, Corbi N, Basilico C, Dailey L (1995) Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Genes Dev 9:2635-2645.
54. Zinn K, Sun QV (1999) Slit branches out: a secreted protein mediates both attractive and repulsive axon guidance. Cell 97:1-4.
55. Zwilling S, Konig H, Wirth T (1995) High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors. EMBO J 14:1198-1208.