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Volumn 164, Issue 12, 2000, Pages 6387-6397

Evidence that terminal deoxynucleotidyltransferase expression plays a role in Ig heavy chain gene segment utilization

Author keywords

[No Author keywords available]

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN J CHAIN;

EID: 0034660137     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.12.6387     Document Type: Article
Times cited : (15)

References (40)
  • 1
    • 0028853297 scopus 로고
    • V(D)J recombination and double-strand break repair
    • Weaver, D. T. 1995. V(D)J recombination and double-strand break repair. Adv. Immunol. 58:29.
    • (1995) Adv. Immunol. , vol.58 , pp. 29
    • Weaver, D.T.1
  • 3
    • 0019214271 scopus 로고
    • Two types of somatic recombination are necessary for the generation of complete heavy chain genes
    • Sakano, H., R. Maki, Y. Kurosawa, W. Roeder, and S. Tonegawa 1980. Two types of somatic recombination are necessary for the generation of complete heavy chain genes. Nature 286:676.
    • (1980) Nature , vol.286 , pp. 676
    • Sakano, H.1    Maki, R.2    Kurosawa, Y.3    Roeder, W.4    Tonegawa, S.5
  • 4
    • 0024691453 scopus 로고
    • V(D)J recombi′ nation: A functional definition of the joining signals
    • Hesse, J. E., M. R. Lieber, K. Mizuuchi, and M. Gellert 1989. V(D)J recombi′ nation: a functional definition of the joining signals. Genes Dev. 3:1053.
    • (1989) Genes Dev. , vol.3 , pp. 1053
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 5
    • 0023409210 scopus 로고
    • Increased frequency of N-region insertion in a murine pre-B cell line infected with a terminal de′ oxynucleotidyltransferase retroviral expression vector
    • Landau, R., D. G. Schatz, M. Rosa, and D. Baltimore. 1987. Increased frequency of N-region insertion in a murine pre-B cell line infected with a terminal de′ oxynucleotidyltransferase retroviral expression vector. Mol. Cell. Biol. 7:3237.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 3237
    • Landau, R.1    Schatz, D.G.2    Rosa, M.3    Baltimore, D.4
  • 6
    • 0024791338 scopus 로고
    • Junctional sequences of T-ceil receptor γδ genes: Implications for γδ T-cell lineages and for a novel intermediate of V(D)J joining
    • Lafaille, J. J., A. DcCloux, M. Bonneville, Y. Takagaki, and S. Tonegawa 1989. Junctional sequences of T-ceil receptor γδ genes: implications for γδ T-cell lineages and for a novel intermediate of V(D)J joining. Cell 59:859.
    • (1989) Cell , vol.59 , pp. 859
    • Lafaille, J.J.1    Dccloux, A.2    Bonneville, M.3    Takagaki, Y.4    Tonegawa, S.5
  • 7
    • 0027535651 scopus 로고
    • P nucleotides in V(D)J recombination: A fine-structure analysis
    • Meier, J. T., and S. M. Lewis. 1993. P nucleotides in V(D)J recombination: a fine-structure analysis. Mol. Cell. Biol. 13:1078.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1078
    • Meier, J.T.1    Lewis, S.M.2
  • 8
    • 77956925714 scopus 로고
    • Terminal deoxynucleotidyltransferase
    • P. Boyer, ed. Academic Press, NY
    • Bollum, F. J. 1974. Terminal deoxynucleotidyltransferase. In The Enzymes, Vol. 10. P. Boyer, ed. Academic Press, NY, pp. 145-171.
    • (1974) The Enzymes , vol.10 , pp. 145-171
    • Bollum, F.J.1
  • 9
  • 10
    • 0026443729 scopus 로고
    • Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny
    • Bogue, M., C. Gilfillan, C. Benoist, and D. Mathis. 1992. Regulation of N-region diversity in antigen receptors through thymocyte differentiation and thymus ontogeny. Proc: Natl. Acad. Sci. USA 89:11011.
    • (1992) Proc: Natl. Acad. Sci. USA , vol.89 , pp. 11011
    • Bogue, M.1    Gilfillan, C.2    Benoist, C.3    Mathis, D.4
  • 12
    • 0021216208 scopus 로고
    • Insertion of N region into heavy chain genes is correlated with expression of terminal deoxynucleotidyltransferase in B cells
    • Desiderio, S. V., G. D. Yancopoulos, M. Paskind, E. Thomas, M. A. Boss, N. Landau, F. W. Alt, and D. Baltimore. 1984. Insertion of N region into heavy chain genes is correlated with expression of terminal deoxynucleotidyltransferase in B cells. Nature 311:752.
    • (1984) Nature , vol.311 , pp. 752
    • Desiderio, S.V.1    Yancopoulos, G.D.2    Paskind, M.3    Thomas, E.4    Boss, M.A.5    Landau, N.6    Alt, F.W.7    Baltimore, D.8
  • 13
    • 0004066515 scopus 로고
    • Lymphoid V(D)J recombination: Nucleotide insertion at signal joints as well as coding joints
    • Lieber, M. R., J. E. Hesse, K. Mizuuchi, and M. Gellen, 1988. Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints. Proc. Natl. Acad. Sci. USA 85:8588.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8588
    • Lieber, M.R.1    Hesse, J.E.2    Mizuuchi, K.3    Gellen, M.4
  • 14
    • 0030795764 scopus 로고    scopus 로고
    • A complex of RAG1 and RAG2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences
    • Grawunder, U., and M. R. Lieber 1997. A complex of RAG1 and RAG2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences. Nucleic Acids Res. 25:1375.
    • (1997) Nucleic Acids Res. , vol.25 , pp. 1375
    • Grawunder, U.1    Lieber, M.R.2
  • 15
    • 0026610950 scopus 로고
    • Predominance of VH-D-JH junctions occurring at sites of short sequence homology results in limited junctional diversity in neonatal antibodies
    • Feeney, A. J. 1992. Predominance of VH-D-JH junctions occurring at sites of short sequence homology results in limited junctional diversity in neonatal antibodies. J. Immunol. 149:222.
    • (1992) J. Immunol. 149:222.
    • Feeney, A.J.1
  • 16
    • 0027234861 scopus 로고
    • Junctional diversity in the absence of N region: Neonatal T cell receptor β chain junctional sequences are more heterogeneous than neonatal T cell receptor γδ or IgH junctions
    • Feeney, A. J. 1993. Junctional diversity in the absence of N region: neonatal T cell receptor β chain junctional sequences are more heterogeneous than neonatal T cell receptor γδ or IgH junctions, J. Immunol. 151:3094.
    • (1993) J. Immunol. , vol.151 , pp. 3094
    • Feeney, A.J.1
  • 17
    • 0028794466 scopus 로고
    • Analysis of homology-directed recombination in VDJ junctions from cytoplasmic Ig-pre-B cells of new-born mice
    • Chukwuocha, R. U., B. Nadel, and A. J. Feeney. 1995. Analysis of homology-directed recombination in VDJ junctions from cytoplasmic Ig-pre-B cells of new-born mice. J. Immunol. 154:1246.
    • (1995) J. Immunol. , vol.154 , pp. 1246
    • Chukwuocha, R.U.1    Nadel, B.2    Feeney, A.J.3
  • 18
    • 0028825461 scopus 로고
    • The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus
    • Zhang, Y., D. Cado, D. M. Asarnow, T. Komori, F. W. Alt, D. H. Raulet, and J. P. Allison. 1995. The role of short homology repeats and TdT in generation of the invariant γδ antigen receptor repertoire in the fetal thymus. Immunity 3:439.
    • (1995) Immunity , vol.3 , pp. 439
    • Zhang, Y.1    Cado, D.2    Asarnow, D.M.3    Komori, T.4    Alt, F.W.5    Raulet, D.H.6    Allison, J.P.7
  • 19
    • 0030588546 scopus 로고    scopus 로고
    • Interdependence of N nucleotide addition and recombination site choice in V(D)J rearrangement
    • Kepler, T. B., M. Borrero, B. Rugerio, S. K McCray, and S. H. Clarke 1996. Interdependence of N nucleotide addition and recombination site choice in V(D)J rearrangement. J. Immunol. 157:4451.
    • (1996) J. Immunol. , vol.157 , pp. 4451
    • Kepler, T.B.1    Borrero, M.2    Rugerio, B.3    McCray, S.K.4    Clarke, S.H.5
  • 20
    • 0031567975 scopus 로고    scopus 로고
    • Constitutive expression of tdt in transgenic mice is sufficient for N region diversity to occur at any Ig locus throughout differentiation
    • Bentolila, L. A., G. E. Wu, F. Nourrit, M. Fanton-d'Andon, F. Rougeon, and N Doyen. 1997. Constitutive expression of TdT in transgenic mice is sufficient for N region diversity to occur at any Ig locus throughout differentiation. J. Immunol. 158:715.
    • (1997) J. Immunol. , vol.158 , pp. 715
    • Bentolila, L.A.1    Wu, G.E.2    Nourrit, F.3    Fanton-D'andon, M.4    Rougeon, F.5    Doyen, N.6
  • 21
    • 0027452074 scopus 로고
    • Mice lacking TdT: Mature animals with an immature lymphocyte repertoire
    • Gilfillan, S., A. Dierich, M. Lemeur, C. Benoist, and D. Mathis. 1993. Mice lacking TdT: mature animals with an immature lymphocyte repertoire. Science 261:1175.
    • (1993) Science , vol.261 , pp. 1175
    • Gilfillan, S.1    Dierich, A.2    Lemeur, M.3    Benoist, C.4    Mathis, D.5
  • 23
    • 0029414789 scopus 로고
    • Mice lacking TdT: Adult mice with fetal antigen receptor repertoire
    • Gilfillan, S., C. Benoist, and D. Mathis. 1995. Mice lacking TdT: adult mice with fetal antigen receptor repertoire, Immunol. Rev. 148:201.
    • (1995) Immunol. Rev. , vol.148 , pp. 201
    • Gilfillan, S.1    Benoist, C.2    Mathis, D.3
  • 24
    • 0027369562 scopus 로고
    • Lack of N regions in antigen-receptor variable region genes of TdT-deficient lymphocytes
    • Komori, T., A. Okada, V. Stewart, and F. W. Alt. 1993. Lack of N regions in antigen-receptor variable region genes of TdT-deficient lymphocytes. Science 261:1171.
    • (1993) Science , vol.261 , pp. 1171
    • Komori, T.1    Okada, A.2    Stewart, V.3    Alt, F.W.4
  • 26
    • 0031572496 scopus 로고    scopus 로고
    • Autoantihodies in mice lacking TdT: Evidence for a role of N region addition in the polyreactivity and in the affinities of anti-DNA antibodies
    • Weller, S., C. Conde, A. M. Knapp, H. Levallois, S. Gilfillan. J. L. Pasquali, and T. Martin. 1997. Autoantihodies in mice lacking TdT: evidence for a role of N region addition in the polyreactivity and in the affinities of anti-DNA antibodies. J. Immunol. 159:3890.
    • (1997) J. Immunol. , vol.159 , pp. 3890
    • Weller, S.1    Conde, C.2    Knapp, A.M.3    Levallois, H.4    Gilfillan, S.5    Pasquali, J.L.6    Martin, T.7
  • 27
    • 0027536627 scopus 로고
    • Human immunoglobulin heavy chain minilocus recombination in transgenic mice: Gene segment utilization in μ and γ transcripts
    • Tuaillon, N., L. D. Taylor, N. Lonberg, P. W. Tucker, and J. D. Capra 1993. Human immunoglobulin heavy chain minilocus recombination in transgenic mice: gene segment utilization in μ and γ transcripts. Proc. Natl. Acad. Sci. USA 90:3720.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3720
    • Tuaillon, N.1    Taylor, L.D.2    Lonberg, N.3    Tucker, P.W.4    Capra, J.D.5
  • 28
    • 0028181484 scopus 로고
    • Biased utilization of DHQ52 and JH4 gene segments in a human immunoglobulin transgenic minilocus is independent of antigenic selection
    • Tuaillon, N., A. B. Miller, N. Lonberg, P. W. Tucker, and J. D. Capra. 1994. Biased utilization of DHQ52 and JH4 gene segments in a human immunoglobulin transgenic minilocus is independent of antigenic selection. J. Immunol. 152:2912.
    • (1994) J. Immunol. , vol.152 , pp. 2912
    • Tuaillon, N.1    Miller, A.B.2    Lonberg, N.3    Tucker, P.W.4    Capra, J.D.5
  • 29
    • 0029053342 scopus 로고
    • Analysis of direct and inverted D-JH rearrangements in a human immunoglobulin heavy chain transgenic minilocus
    • Tuaillon, N, A. B. Miller, P. W. Tucker, and J. D. Capra. 1995. Analysis of direct and inverted D-JH rearrangements in a human immunoglobulin heavy chain transgenic minilocus. J. Immunol. 154:6453.
    • (1995) J. Immunol. , vol.154 , pp. 6453
    • Tuaillon, N.1    Miller, A.B.2    Tucker, P.W.3    Capra, J.D.4
  • 30
    • 0008370020 scopus 로고
    • VHDJH recombination in a human immunoglobulin heavy chain transgenic minilocus
    • Tuaillon, N., P. W. Tucker, and J. D. Capra. 1995. VHDJH recombination in a human immunoglobulin heavy chain transgenic minilocus. Immunologist 3:269.
    • (1995) Immunologist , vol.3 , pp. 269
    • Tuaillon, N.1    Tucker, P.W.2    Capra, J.D.3
  • 31
    • 0008343923 scopus 로고
    • V(D)J recombination, class-switching and somatic mutation in human immunoglobulin minilocus transgenic mice
    • J. D. Capra and M. Zanetti. eds. Gordon & Breach, New York
    • Tuaillon, N., and J. D. Capra. 1995. V(D)J recombination, class-switching and somatic mutation in human immunoglobulin minilocus transgenic mice. In The Antibodies. J. D. Capra and M. Zanetti. eds. Gordon & Breach, New York, pp. 1-39.
    • (1995) The Antibodies , pp. 1-39
    • Tuaillon, N.1    Capra, J.D.2
  • 32
    • 0032539691 scopus 로고    scopus 로고
    • -/- mice carrying a human immunoglobulin heavy chain transgenic minilocus
    • -/- mice carrying a human immunoglobulin heavy chain transgenic minilocus. Proc. Natl. Acad. Sci. USA 95:1703.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1703
    • Tuaillon, N.1    Capra, J.D.2
  • 33
    • 0027461764 scopus 로고
    • Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V(D)J joining
    • Pandey, A., L. W. Tjoelker, and C. B. Thompson. 1993. Restricted immunoglobulin junctional diversity in neonatal B cells results from developmental selection rather than homology-based V(D)J joining. J. Exp. Med. 177:329.
    • (1993) J. Exp. Med. , vol.177 , pp. 329
    • Pandey, A.1    Tjoelker, L.W.2    Thompson, C.B.3
  • 34
    • 0033565878 scopus 로고    scopus 로고
    • Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase
    • Mickelsen, S., C. Snyder, K. Trujillo, M. Bogue, D. B. Roth, and K. Meek. 1999. Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase. J. lmmunol. 163:834.
    • (1999) J. Lmmunol. , vol.163 , pp. 834
    • Mickelsen, S.1    Snyder, C.2    Trujillo, K.3    Bogue, M.4    Roth, D.B.5    Meek, K.6
  • 36
    • 0032185230 scopus 로고    scopus 로고
    • DNA ligase Iv is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes
    • Grawunder, U. D Zimmer. S. Fugmann. K. Schwarz, and M. R. Lieber. 1998. DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol. Cell 2:477.
    • (1998) Mol. Cell , vol.2 , pp. 477
    • Grawunder1    Zimmer, U.D.2    Fugmann, S.3    Schwarz, K.4    Lieber, M.R.5
  • 37
    • 0027237601 scopus 로고
    • Coding end sequence can markedly affect the initiation of V(D)J recombination
    • Gerstein, R. M., and M. R. Lieber. 1993. Coding end sequence can markedly affect the initiation of V(D)J recombination. Genes Dev 7:1459.
    • (1993) Genes Dev , vol.7 , pp. 1459
    • Gerstein, R.M.1    Lieber, M.R.2
  • 38
    • 0028956147 scopus 로고
    • Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination
    • Ezekiel, U. R., P. Engler, D. Stern, and U. Storb. 1995. Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination. Immunity 2:381.
    • (1995) Immunity , vol.2 , pp. 381
    • Ezekiel, U.R.1    Engler, P.2    Stern, D.3    Storb, U.4
  • 39
    • 0030293631 scopus 로고    scopus 로고
    • Immunoglobulin D(H) recombination signal sequence targeting: Effect of D(H) coding and flanking regions and recombination partner
    • VanDyk, L. F., T. W. Wise, B. B. Moore, and K. Meek. 1996. Immunoglobulin D(H) recombination signal sequence targeting: effect of D(H) coding and flanking regions and recombination partner. J. Immunol. 157:4005.
    • (1996) J. Immunol. , vol.157 , pp. 4005
    • Vandyk, L.F.1    Wise, T.W.2    Moore, B.B.3    Meek, K.4
  • 40
    • 0030984706 scopus 로고    scopus 로고
    • The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences
    • Ezekiel, U. R., T. Sun, G. Bozek, and U. Storb. 1997. The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences. Mol. Cell. Biol. 17:4191.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4191
    • Ezekiel, U.R.1    Sun, T.2    Bozek, G.3    Storb, U.4


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