Stimulus- and cell-type-specific regulation of CCAAT-enhancer binding protein isoforms in glomerular mesangial cells by lipopolysaccharide and cytokines

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1501, Issue 2-3, 2000, Pages 171-179

  Granger, Rachel L ^a   Hughes, Timothy R ^a   Ramji, Dipak P ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

CCAAT enhancer binding protein; Cytokine; Gene expression; Lipopolysaccharide; Mesangial cell

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; GENE EXPRESSION; GLOMERULONEPHRITIS; MESANGIUM; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; CYTOKINES; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GLOMERULAR MESANGIUM; KIDNEY DISEASES; LIPOPOLYSACCHARIDES; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RATS, WISTAR; RNA, MESSENGER;

EID: 0034660026     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(00)00016-8     Document Type: Article

References (28)

1. Sedor J.R., Konieczkowski M., Huang S., Gronich J.H., Nakazato Y., Gordon G., King C.H. Cytokines, mesangial cell activation and glomerular injury. Kidney Int. 43:1993;S65-S70.
2. Ooi B.S., Cohen D.J., Veis J.H. Biology of the mesangial cell in glomerulonephritis: role of cytokines. Proc. Soc. Exp. Biol. Med. 213:1996;230-237.
3. Johnson R.J. Cytokines, growth factors and renal injury: where do we go now? Kidney Int. 52:1997;S2-S6.
4. Lovett D.H., Bursten S.L., Gemsa D., Bessler W., Resch K., Ryan J.L. Activation of glomerular mesangial cells by Gram-negative bacterial cell wall components. Am. J. Physiol. 133:1988;472-484.
5. Wedel A., Ziegler-Heitbrock H.W.L. The C/EBP family of transcription factors. Immunobiology. 193:1995;171-185.
6. Yamanaka R., Lekstromhimes J., Barlow C., Wynshawboris A., Xanthopoulos K.G. CCAAT enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis. Int. J. Mol. Med. 1:1998;213-221.
7. Poli V. The role of C/EBP isoforms in the control of inflammatory and native immunity functions. J. Biol. Chem. 273:1998;29279-29282.
8. A. Mire-Sluis, R. Thorpe (Eds.), Cytokines, Academic Press, London, 1998.
9. Kakizaki Y., Kraft N., Atkins R.C. Interferon-gamma stimulates the secretion of IL-1, but not of IL-6, by glomerular mesangial cells. Clin. Exp. Immunol. 91:1993;521-525.
10. Kunz D., Walker G., Eberhardt W., Messmer U.K., Huwiler A., Pfeilschifter J. Platelet-derived growth factor and fibroblast growth factor differentially regulate interleukin-1 beta- and cAMP-induced nitric oxide synthase expression in rat renal mesangial cells. J. Clin. Invest. 100:1997;2800-2809.
11. 2 gene expression by interleukin-1 and forskolin in mesangial cells. FEBS Lett. 291:1991;249-252.
12. Kusner D.J., Luebbers E.L., Nowinski R.J., Konieczkowski M., King C.H., Sedor J.R. Cytokine-induced and LPS-induced synthesis of interleukin-8 from human mesangial cells. Kidney Int. 39:1991;1240-1248.
13. Descombes P., Schibler U. A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA. Cell. 67:1991;569-575.
14. Ossipow V., Descombes P., Schibler U. CCAAT/enhancer-binding protein mRNA is translated into multiple proteins with different transcription activation potentials. Proc. Natl. Acad. Sci. USA. 90:1993;8219-8223.
15. Eberhardt W., Plúss C., Hummel R., Pfeilschifter J. Molecular mechanisms of inducible nitric oxide synthase gene expression by IL-1β and cAMP in rat mesangial cells. J. Immunol. 160:1998;4961-4969.
16. Nakazato Y., Hayashida T., Kanno Y., Sasamura H., Okada H., Suzuki H., Saruta T. Interleukin (IL)-1 and IL-4 synergistically stimulate NF-IL6 activity and IL-6 production in human mesangial cells. Kidney Int. 54:1998;71-79.
17. Foidart J.B., Dechenne C.A., Mahieu P., Creutz C.E., DeMey J. Tissue culture of normal rat glomeruli: isolation and morphological characterisation of two homogenous cell lines. Invest. Cell. Pathol. 2:1979;15-26.
18. Tengku-Muhammad T.S., Hughes T.R., Cryer A., Ramji D.P. Differential regulation of lipoprotein lipase in the macrophage J774.2 cell line by cytokines. Cytokine. 8:1996;525-533.
19. Tengku-Muhammad T.S., Cryer A., Ramji D.P. Synergism between lipopolysaccharide and interferon-γ in the regulation of lipoprotein lipase in macrophages. Cytokine. 11:1999;408-415.
20. Sabatakos G., Davies G.E., Grosse M., Cryer A., Ramji D.P. Expression of the genes encoding CCAAT- enhancer binding protein isoforms in the mouse mammary gland during lactation and involution. Biochem. J. 334:1998;205-210.
21. Marti A., Jehn B., Costello E., Keon N., Ke G., Martin F., Jaggi R. Protein kinase A and AP-1 (c-Fos/JunD) are induced during apoptosis of mouse mammary epithelial cells. Oncogene. 9:1994;1213-1223.
22. Ramji D.P., Vitelli A., Tronche F., Cortese R., Ciliberto G. The two C/EBP isoforms, IL-6DBP/NF-IL6 and C/EBPδ/NF-IL6β, are induced by IL-6 to promote acute-phase gene transcription via different mechanisms. Nucleic Acids Res. 21:1994;289-294.
23. 2 in rat mesangial cells. Biochim. Biophys. Acta. 1355:1997;315-322.
24. Poli V., Mancini F.P., Cortese R. IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell. 63:1990;643-653.
25. Hu H.-M., Baer M., Williams S.C., Johnson P.F., Schwartz R.C. Redundancy of C/EBPα, -β, and -δ in supporting the lipopolysaccharide-induced transcription of IL-6 and monocyte chemoattractant protein-1. J. Immunol. 160:1998;2334-2342.
26. Yin M., Yang S.Q., Lin H.Z., Lane M.D., Chatterjee S., Diehl A.M. Tumor necrosis factor α promotes nuclear localization of cytokine-inducible CCAAT/enhancer binding protein isoforms in hepatocytes. J. Biol. Chem. 271:1996;17974-17978.
27. Akira S., Kishimoto T. IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol. Rev. 127:1992;25-50.
28. Buck M., Poli V., vanderGeer P., Chojkier M., Hunter T. Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBPβ is required for hepatocyte proliferation induced by TGF-α Mol. Cell. 4:1999;1087-1092.