Iron overload and kidney lysosomes

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1501, Issue 2-3, 2000, Pages 138-148

  Dimitriou, E ^a   Kairis, M ^b   Sarafidou, J ^a   Michelakakis, H ^a  

^a Institute of Child Health   (Greece)

^b P AND A KYRIAKOU CHILDREN S HOSPITAL   (Greece)

Author keywords

Iron overload; Kidney lysosome; Lysosomal enzyme

Indexed keywords

IRON DEXTRAN; LYSOSOME ENZYME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FRACTIONATION; CELL ORGANELLE; CONTROLLED STUDY; IRON OVERLOAD; KIDNEY; KIDNEY HOMOGENATE; KIDNEY INJURY; LIVER; LYSOSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN;

EID: 0034659995     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4439(00)00019-3     Document Type: Article

References (31)

1. Zaino E.C. Pathophysiology of thalassemia, 4th Cooley's Anemia Symposium. Ann. NY Acad. Sci. 344:1980;284-393.
2. Weinberg E.D. Cellular iron metabolism in health and disease. Drug Metab. Rev. 22:1990;531-579.
3. Bonkovsky H.L. Iron and the Liver. Am. J. Med. Sci. 301:1991;32-43.
4. Glaumann H., Jansson H., Arborgh B., Ericsson J.L.E. Isolation of liver lysosomes by iron loading. J. Cell Biol. 67:1975;887-894.
5. Peters T.J., Seymour C.A. Acid hydrolase activities and lysosomal integrity in liver biopsies from patients with iron overload. Clin. Sci. Mol. Med. 50:1976;75-78.
6. Hultcrantz R., Ahlberg J., Glaumann H. Isolation of two lysosomal populations from iron-overloaded rat liver with different iron concentration and proteolytic activity. Virchows Arch. 47:1984;55-65.
7. Bacon B.R., Britton R.S. The pathology of hepatic iron overload: A free radical-mediated process? Hepatology. 11:1990;127-137.
8. Myers B.M., Prendergast F.G., Holman R., Kuntz S.M., LaRusso N.F. Alterations in the structrure, physicochemical properties and pH of hepatocyte lysosomes in experimental iron overload. J. Clin. Invest. 88:1991;1207-1215.
9. LeSage G.D., Kost L.J., Barham S.S., LaRusso N.F. Biliary excretion of iron from hepatocyte lysosomes in the rat. J. Clin. Invest. 77:1986;90-97.
10. Richter G.W. Iron overload nephropathy in rats. Path. Res. Pract. 168:1980;84-106.
11. Alfrey A.C., Hammond W.S. Renal iron handling in the nephrotic syndrome. Kidney Int. 37:1990;1409-1413.
12. Nankivell B.J., Boadle R.A., Harris D.C.H. Iron accumulation in human chronic renal disease. Am. J. Kidney Dis. 20:1992;580-584.
13. Alfrey A.C. Role of iron and oxygen radicals in the progression of chronic renal failure. Am. J. Kidney Dis. 23:1994;183-187.
14. Nankivell B.J., Tay Y.C., Boadle R.A., Harris D.C.H. Dietary protein alters tubular iron accumulation after partial nephrectomy. Kidney Int. 45:1994;1006-1013.
15. Michelakakis H., Dimitriou E., Georgakis H., Karabatsos F., Fragodimitri C., Saraphidou J., Premetis E., Karagiorga-Lagana M. Iron overload and urinary lysosomal enzyme levels in β-thalassaemia major. Eur. J. Pediat. 156:1997;602-604.
16. R.D. Lillie, H.M. Fullmer, Endogenous pigments, in: Histopathologic Technic and Practical Histochemistry, McGraw-Hill, New York, 1976, p. 507.
17. Shibko S., Tappel A.L. Rat-kidney lysosomes: Isolation and properties. Biochem. J. 95:1965;731-741.
18. Harikumar P., Reeves J.P. The lysosomal proton pump is electrogenic. J. Biol. Chem. 258:1983;10403-10410.
19. S.K. Srivastava, Tay-Sachs and Sandhoff diseases, in: R.H. Glew, S.P. Peters (Eds.), Practical Enzymology of the Sphingolipidoses, Alan R. Liss, New York, 1977, pp. 217-241.
20. Hirani S., Winchester B.G., Patrick A.D. Measurement of the α-mannosidase activities in human plasma by differential assay. Clin. Chim. Acta. 81:1977;135-144.
21. 1-gangliosidosis, in: R.H. Glew, S.P. Peters (Eds.), Practical Enzymology of the Spingolipidoses, Alan R. Liss, New York, 1977, pp. 101-136.
22. Hers H.G., Beaufay H., de Duve C. L'analyse simultanée des hexoses, des trioses et de leurs esters phosphorés. Biochim. Biophys. Acta. 11:1953;416-426.
23. E.J. King, I.D.P. Wooton, Microanalysis in Medical Biochemistry, Churchill, London, 1959.
24. Plummer T.D., Wilkinson H.J. Organs specifity and lactate dehydrogenase activity 2. Some properties of human-heart and liver preparations. Biochem. J. 87:1963;423-429.
25. Appelmans F., Wattiaux R., de Duve C. Tissue fractionation studies 5. The association of acid phosphatase with a special class of cytoplasmic granules in rat liver. Biochem. J. 59:1955;438-445.
26. Lowry O., Rosebrough N., Farr A., Randall R. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193:1951;265-275.
27. Seymour C.A., Peters T.J. Organelle pathology in primary and secondary haemochromatosis with special reference to lysosomal changes. Br. J. Haematol. 40:1978;239-253.
28. Powell L.W., Basset M.L., Halliday J.W. Hemochromatosis 1980 Update. Gastroenterology. 78:1980;374-381.
29. Mak I.T., Weglicki W.B. Characterization of iron-mediated peroxidative injury in isolated hepatic lysosomes. J. Clin. Invest. 75:1985;58-63.
30. Ong-ajyooth L., Malasit P., Ong-ajyooth S., Fucharoen S., Potrakul P., Vasuvattakul S., Siritanaratkul N., Nilwarangkur S. Renal function in adult beta-thalassemia/HβE disease. Nephron. 78:1998;156-161.
31. Young S.P., Roberts S., Bomford A. Intracellular processing of transferrin and iron by isolated rat hepatocytes. Biochem. J. 232:1985;819-823.