Low-dose methotrexate for the treatment of patients with large granular lymphocyte leukemia associated with rheumatoid arthritis

American Journal of Medicine

Volumn 108, Issue 9, 2000, Pages 730-732

  Hamidou, Mohamed A ^a,c   Bani Sadr, Firouze ^a   Lamy, Thierry ^b   Raffi, François ^a   Grolleau, Jean Yves ^a   Barrier, Jacques H ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b RENNES UNIVERSITY HOSPITAL   (France)

^c HÔTEL DIEU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

METHOTREXATE; PENICILLAMINE; T LYMPHOCYTE RECEPTOR;

ADULT; AGED; ARTICLE; CASE REPORT; DISEASE ASSOCIATION; DOSE CALCULATION; DRUG EFFECT; FEMALE; HUMAN; LARGE GRANULAR LYMPHOCYTE; LYMPHATIC LEUKEMIA; NATURAL KILLER CELL; PRIORITY JOURNAL; REMISSION; RHEUMATOID ARTHRITIS;

AGED; ANTIMETABOLITES, ANTINEOPLASTIC; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; LEUKEMIA, MYELOID; LEUKOCYTE COUNT; LYMPHOCYTE COUNT; METHOTREXATE; MIDDLE AGED; NEUTROPHILS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 0034659173     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9343(00)00406-X     Document Type: Article

References (27)

1. Loughran T.P. Jr. Clonal diseases of large granular lymphocytes. Blood. 82:1993;1-14.
2. Scott C.S., Richards S.J., Sivakumaran M. Disorders of large granular lymphocytes and natural killer-associated cells. Blood. 83:1994;301-303.
3. McKenna R.W., Parkin J., Kersey J.H., et al. Chronic lymphoproliferative disorder with unusual clinical, morphologic, ultrastructural and membrane surface marker characteristics. Am J Med. 62:1977;588-596.
4. Harris N.L., Jaffe E.S., Stein H. A revised European-American classification of lymphoid neoplasms a proposal from the International Lymphoma Study Group . Blood. 84:1994;1361-1392.
5. Loughran T.P. Jr, Starkebaum G., Kidd P., Neiman P. Clonal proliferation of large granular lymphocytes in rheumatoid arthritis. Arthritis Rheum. 31:1988;31.
6. Snowden N., Bhavnani M., Swinson D.R., et al. Large granular T lymphocytes, neutropenia, and polyarthropathy. An under diagnosed syndrome? Q J Med. 78:1991;65-76.
7. Dhodapkar M.V., Li C.-Y., Lust J.A., et al. Clinical spectrum of clonal proliferations of T-large granular lymphocytes a T-cell clonopathy of undetermined significance? Blood. 84:1994;1620-1627.
8. Starkebaum G., Loughran T.P. Jr, Gaur L.K. Immunogenetic similarities between patients with Felty's syndrome and those with clonal expansions of large granular lymphocytes in rheumatoid arthritis. Arthritis Rheum. 40:1997;624-626.
9. Bowman S.J., Sivakumaran M., Snowden N., et al. The large granular lymphocyte syndrome with rheumatoid arthritis. Immunogenetic evidence for a broader definition of Felty's syndrome. Arthritis Rheum. 37:1994;1326-1330.
10. Bowman S.J., Hall M.A., Panayi G.S., Lanchbury J.S. T cell receptor α-chain and β-chain junctional region homology in clonal CD3+, CD8+ T lymphocyte expansions in Felty's syndrome. Arthritis Rheum. 40:1997;615-623.
11. Weinblatt M.E., Kaplan H., Germain B.F., et al. Methotrexate in rheumatoid arthritis. A five-year prospective multicenter study. Arthritis Rheum. 37:1994;1492-1498.
12. Wassenberg S., Herborn G., Rau R. Methotrexate treatment in Felty's syndrome. Br J Rheumatol. 37:1998;908-911.
13. Gerster J.C. Longterm effect of methotrexate in Felty's syndrome a 12 year followup . J Rheumatol. 23:1996;200.
14. Fiechtner J.J., Miller D.R., Starkebaum G. Reversal of neutropenia with methotrexate treatment in patients with Felty's syndrome. Correlation of response with neutrophil-reactive IgG. Arthritis Rheum. 32:1989;194-201.
15. Loughran T.P. Jr, Kidd P.G., Starkebaum G. Treatment of large granular lymphocyte leukemia with oral low-dose methotrexate. Blood. 84:1994;2164-2170.
16. Arnett F.C., Edworthy S.M., Bloch D.A., et al. The American Rheumatism Association revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 31:1988;315-324.
17. Lust J.A., Letendre L., Thibodeau S.N. Marrow hypoplasia associated with a monoclonal CD8 large granular lymphocyte proliferation reversal with cyclophosphamide and prednisone . Am J Med. 87:1989;214-217.
18. Sood R., Stewart C.C., Aplan P.D., et al. Neutropenia associated with T-cell large granular lymphocyte leukemia long-term response to cyclosporine therapy despite persistence of abnormal cells . Blood. 91:1998;3372-3378.
19. Lamy T., LePrise P.Y., Amiot L., et al. Response to granulocyte-macrophage colony-stimulating factor (GM-CSF) but not to G-CSF in a case of agranulocytosis associated with large granular lymphocyte (LGL) leukemia. Blood. 85:1995;3352-3353.
20. Meliconi R., Kingsley G.H., Pitzalis C., et al. Analysis of lymphocyte phenotype and T cell receptor genotype in Felty's syndrome. J Rheumatol. 19:1992;1058-1064.
21. Dupuy d'Angeac A., Monier S., Jorgensen C., et al. Increased percentage of CD3+, CD57+, lymphocytes in patients with rheumatoid arthritis correlation with duration of disease . Arthritis Rheum. 36:1993;608-612.
22. Bucht A., Larson P., Weisbrot L., et al. Expression of interferon γ, IL-10, IL-12 and transforming growth factor β m-RNA in synovial cells from patients in the early and late phases of rheumatoid arthritis. Clin Exp Rheumatol. 103:1996;357-367.
23. McInnes I.B., Al-Mughales J., Field M., et al. The role of interleukin-15 in T-cell migration and activation in rheumatoid arthritis. Nature Med. 2:1996;175-182.
24. Gentile T.C., Loughran T.P. Jr. Interleukin-12 is a costimulatory cytokine for leukemic CD3+ large granular lymphocytes. Cell Immunol. 166:1995;158-161.
25. Zambello R., Facco M., Trentin L., et al. Interleukin-15 triggers the proliferation, and cytotoxicity of granular lymphocytes in patients with lymphoproliferative disease of granular lymphocytes. Blood. 89:1997;201-211.
26. Cronstein B.N. Methotrexate and its mechanism of action. Arthritis Rheum. 39:1996;1951-1960.
27. Genestier L., Paillot R., Fournel S., et al. Immunosuppressive properties of methotrexate apoptosis and clonal deletion of activated peripheral T cells . J Clin Invest. 102:1998;322-328.