A new asymmetric route to substituted piperidines: Synthesis of N-alkyl- 3,4-dihydroxy-5-alkylpiperidines

Tetrahedron Letters

Volumn 41, Issue 16, 2000, Pages 2801-2804

  Sun, Hongbin ^a   Millar, Kim M ^a   Yang, Jingsong ^a   Abboud, Khalil ^a   Horenstein, Benjamin A ^a  

^a University of Florida ^*  (United States)

Author keywords

Alkylation; Asymmetric synthesis; Hydrazones; Piperidinone

Indexed keywords

HYDRAZONE DERIVATIVE; PIPERIDINE DERIVATIVE; PIPERIDONE DERIVATIVE;

ALKYLATION; ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0034655850     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(00)00267-7     Document Type: Article

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12. ++H): 218.1392; found: 218.1392.
13. We tried to use various chiral shift reagents to directly determine the enantiomeric purity of 9a, 9b, 17a and 17b, but were unable to obtain satisfactory results.