Two phospholipase A2 inhibitors from the plasma of Cerrophidion (Bothrops) godmani which selectively inhibit two different group-II phospholipase A2 myotoxins from its own venom: Isolation, molecular cloning and biological properties

Biochemical Journal

Volumn 346, Issue 3, 2000, Pages 631-639

  Lizano, Sergio ^a   Angulo, Yamileth ^a   Lomonte, Bruno ^a   Fox, Jay W ^b   Lambeau, Gérard ^c   Lazdunski, Michel ^c   Gutiérrez, José María ^a  

^a UNIVERSIDAD DE COSTA RICA   (Costa Rica)

^b UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^c INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Carbohydrate recognition domain; Crotalinae; Myotoxicity; Three finger domain; Toxin inhibitor

Indexed keywords

ACID PROTEIN; COMPLEMENTARY DNA; GLYCOSYLATED PROTEIN; OLIGOMER; PHOSPHOLIPASE A2; PHOSPHOLIPASE A2 INHIBITOR; SNAKE VENOM; ENZYME INHIBITOR; GLYCOPROTEIN; MIP I PROTEIN, CERROPHIDION GODMANI; MIP II PROTEIN, CERROPHIDION GODMANI; MIP-I PROTEIN, CERROPHIDION GODMANI; MIP-II PROTEIN, CERROPHIDION GODMANI; PHOSPHOLIPASE A;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CYTOLYSIS; DNA SEQUENCE; EDEMA; ENZYME INHIBITION; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ISOLATION; SEQUENCE HOMOLOGY; TOXIN STRUCTURE; ANIMAL; BLOOD; DRUG ANTAGONISM; ENZYMOLOGY; GENETICS; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SNAKE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BOTHROPS; CLONING, MOLECULAR; CROTALID VENOMS; DNA, COMPLEMENTARY; ENZYME INHIBITORS; GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PHOSPHOLIPASES A; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0034653917     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3460631     Document Type: Article

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