LST1: A gene with extensive alternative splicing and immunomodulatory function

Journal of Immunology

Volumn 164, Issue 6, 2000, Pages 3169-3176

  Rollinger Holzinger, Ingrid ^a,g   Eibl, Brigitte ^b   Pauly, Marc ^a   Griesser, Ute ^b   Hentges, François ^c   Auer, Bernhard ^d   Pall, Georg ^a   Schratzberger, Peter ^a   Niederwieser, Dietger ^e   Weiss, Elisabeth H ^f   Zwierzina, Heinz ^a  

^a Lab Rech Cancer Maladies du Sang   (Luxembourg)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c Centre Hospitalier   (Luxembourg)

^d UNIVERSITY OF INNSBRUCK   (Austria)

^e UNIVERSITY OF LEIPZIG   (Germany)

^f LMU Munich   (Germany)

^g UNIVERSITY OF LUXEMBOURG   (Luxembourg)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; B LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOMODULATION; LEUKOCYTE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING; SEQUENCE HOMOLOGY; T LYMPHOCYTE;

EID: 0034653394     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.6.3169     Document Type: Article

References (21)

1. Tsuge, I., F. W. Shen, M. Steinmetz, and E. A. Boyse. 1987. A gene in the H-2S:H-2D interval of the major histocompatibility complex which is transcribed in B cells and macrophages. Immunogenetics 26:378.
2. Holzinger, I., A. de Baey, G. Messer, G. Kick, H. Zwierzina, and E. H. Weiss. 1995. Cloning and genomic characterization of LST1: a new gene in the human TNF region. Immunogenetics 42:315.
3. Messer, G., U. Spengler, M. Jung, G. Honold, K. Bloehmer, G. Pape, G. Riethmüller, and E. H. Weiss. 1991. Polymorphic structure of the tumor necrosis factor (TNF) locus: an Ncol polymorphism in the first intron of the human TNF-β gene correlates with a variant amino acid in position 26 and a reduced level of TNF-β production. J. Exp. Med. 173:209.
4. Gruen, R., and S. Weissman. 1997. Evolving views of the major histocompatibility complex. Blood 90:4252.
5. Browning, J. L., A. Ngam-ek, P. Lawton, J. DeMarinis, R. Tizard, E. P. Chow, C. Hession, B. O'Brine-Greco, S. F. Foley, and C. F. Ware. 1993. Lymphotoxin β a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell 72:847.
6. Nalabolu, S. R., H. Shukla, G. Nallur, S. Parimoo, and S. M. Weissman. 1996. Genes in a 220-kb region spanning the TNF cluster in the human MHC. Genomics 31:215.
7. Udalova, I. A., S. A. Nedospasov, O. C. Webb, D. D. Chaplin, and R. L. Turetskaya. 1993. Highly informative typing of the human TNF locus using six adjacent polymorphic markers. Genomics 16:180.
8. de Baey, A., I. Holzinger, S. Scholz, E. Keller, and E. H. Weiss. 1995. Pvull polymorphism in the primate homologue of the mouse B144 (Lst1). Hum. Immunol. 42:9.
9. Middleton, P. G., P. R. A. Taylor, G. Jackson, S. J. Proctor, A. M. Dickinson. 1998. Cytokine gene polymorphisms associating with severe acute graft-versus-host disease in HLA-identical sibling transplants. Blood 92:3943.
10. Asano, H., T. Kobayashi, K. Uchida, S. Hayashi, I. Yokoyama, H. Inoko, H. Takagi. 1997. Significance of tumor necrosis factor microsatellite polymorphism in renal transplantation. Tissue Antigens 50:484.
11. de Baey, A., B. Fellerhoff, S. Maier, S. Martinozzi, U. Weidle, and E. H. Weiss. 1997. Complex expression pattern of the TNF region LST1 gene through differential regulation, initiation, and alternative splicing. Genomics 45:591.
12. Lea, T., F. Vartdal, C. Davies, and J. Ugelstad. 1985. Magnetic monosized polymer panicles for fast and specific fractionation of human mononuclear cells. Scand. J. Immonol. 22:207.
13. + B lymphocytes positively selected from buffy coats by immunomagnetic separation. Eur. J. Immunol. 20:201.
14. + T cells: positive selection with monoclonal antibodies directly conjugated to monosized microspheres. J. Immunol. Methods 90: 179.
15. Rasmussen, A., E. Smeland, B. Erikstein, L. Caignault, and S. Funderud. 1992. A new method for detachment of Dynabeads from positively selected B lymphocytes. J. Immunol. Methods 146:195.
16. Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α. J. Exp. Med. 179:1109.
17. Romani, N., S. Gruner, D. Brang, E. Kämpgen, A. Lenz, B. Trockenbacher. G. Konwalinka, P. Fritsch, R. Steinman, and G. Schuler. 1994. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180:83.
18. + human blood dendritic cells for active tumor immunotherapy. Exp. Hematol. 25:232.
19. Rollinger-Holzinger, I., U. Griesser, V. Pollack, and H. Zwierzina. 1998. Expression and regulation of the thrombopoietin receptor variants MPLP and MPLK in PBMC. Cytokine 10:795.
20. Holzinger, A., K. S. Phillips, and T. E. Weaver. 1996. Single-step purification/solubilization of recombinant proteins: application to surfactant protein B. BioTechniques 20:804.
21. + mononuclear cells in autologous and allogeneic MLR. J. Immunol. 127:726.