CD47 engagement inhibits cytokine production and maturation of human dendritic cells

Journal of Immunology

Volumn 164, Issue 4, 2000, Pages 2193-2199

  Demeure, C E ^a   Tanaka, H ^a   Mateo, V ^a   Rubio, M ^a   Delespesse, G ^a   Sarfati, M ^a  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD47 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 12; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; BINDING SITE; CELL MATURATION; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL;

EID: 0034652002     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.4.2193     Document Type: Article

References (49)

1. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
2. Austyn, J. M. 1998. Dendritic cells. Curr. Opin. Hematol. 5:3.
3. Inaba, K., S. Turley, F. Yamaide, T. Iyoda, K. Mahnke, M. Inaba, M. Pack, M. Subklewe, B. Sauter, D. Sheff, et al. 1998. Efficient presentation of phagocytosed cellular fragments on the major histocompatibility complex class II products of dendritic cells. J. Exp. Med. 188:2163.
4. Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor α J. Exp. Med. 179:1109.
5. Sallusto, F., A. Lanzavecchia, and C. R. Mackay. 1998. Chemokines and chemokine receptors in T-cell priming and Th1/Th2-mediated responses. Immunol. Today 19:568.
6. Reis e Sousa, C., A. Sher, and P. Kaye. 1999. The role of dendritic cells in the induction and regulation of immunity to microbial infection. Curr. Opin. Immunol. 11:392.
7. Gately, M. K., L. M. Renzetti, J. Magram, A. S. Stem, L. Adorini, U. Gubler, and D. H. Presky. 1998. The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses. Annu. Rev. Immunol. 16:495.
8. Palucka, K., and J. Banchereau. 1999. Linking innate and adaptive immunity. Nat. Med. 5:868.
9. Trinchieri, G. 1997. Cytokines acting on or secreted by macrophages during imracellular infection (IL-10. IL-12, IFN-γ). Curr. Opin. Immunol. 9:17.
10. de Vries, J. E. 1998. The role of IL-13 and its receptor in allergy and inflammatory responses. J. Allergy Clin. Immunol. 102:165.
11. Takeuchi, M., P. Alard, and J. W. Streilein. 1998. TGF-β promotes immune deviation by altering accessory signals of antigen-presenting cells. J. Immunol. 160:1589.
12. 2 is a potent inhibitor of human interleukin 12 production. J. Exp. Med. 181:775.
13. Vieira, P. L., P. Kalinski, E. A. Wierenga, M. L. Kapsenberg, and E. C. de Jong. 1998. Glucocorticoids inhibit bioactive IL-12p70 production by in vitro-generated human dendritic cells without affecting their T cell stimulatory potential. J. Immunol. 161:5245.
14. Marth, T., and B. L. Kelsall. 1997. Regulation of interleukin-12 by complement receptor 3 signaling. J. Exp. Med. 185:1987.
15. Sutterwala, F. S., G. J. Noel, R. Clynes, and D. M. Moser. 1997. Selective suppression of interleukin-12 induction after macrophage receptor ligation. J. Exp. Med 185:1977.
16. Buelens, C., V. Verhasselt, D. De Groote, K. Thielemans, M. Goldman, and F. Willems. 1997. Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor. Eur. J Immunol. 27:756.
17. Enk, A. H., V. L., Angeloni, M. C. Udey, and M. C. Katz. 1993. Inhibition of Langerhans cell antigen-presenting function by IL-10: a role for IL-10 in induction of tolerance. J. Immunol. 151: 2390.
18. De Smedt, T., M. Van Mechelen, G. De Becker, J. Urbain, O. Leo, and M. Moser. 1997. Effect of interleukin-10 on dendritic cell maturation and function. Eur. J. Immunol. 27:1229.
19. + T cells to secrete IL-4. Int. Immunol. 10:1017.
20. Geissmann, F., P. Revy, A. Regnault, Y. Lepelletier, M. Dy, N. Brousse, S. Amigorena, O. Hermine, and A. Durandy. 1999. TGF-β1 prevents the non-cognate maturation of human dendritic Langerhans cells. J. Immunol. 162:4567.
21. Piemonti, L., P. Monti, P. Allavena, M. Sironi, L. Soldini, B. E. Leone, C. Socci, and V. Di Carlo. 1999. Glucocorticoids affect human dendritic cell differentiation and maturation. J. Immunol. 162:6473.
22. 3-dependent ligand binding. J. Cell Biol. 123:485.
23. Lindberg, F. P., H. D. Gresham, M. I. Reinhold, and E. J. Brown. 1996. Integrin-associated protein immunoglobulin domain is necessary for efficient vitronectin bead binding. J. Cell Biol. 134:1313.
24. Lindberg, F. P., D. C. Bullard, T. E. Caver, H. D. Gresham, A. L. Beaudet, and E. J. Brown. 1996. Decreased resistance to bacterial infection and granulocyte defects in IAP-deficient mice. Science 274:795.
25. Cooper, D., F. P. Lindberg. J. R. Gamble, E. J. Brown, and M. A. Vadas. 1995. Transendothelial migration of neutrophils involves integrin-associated protein (CD47). Proc. Natl. Acad. Sci. USA 92:3978.
26. 1, integrins regulates lymphocyte migration on vascular cell adhesion molecule 1. Eur. J. Immunol. 27:3242.
27. Gao, A.-G., F. P. Lindberg, M. B. Finn, S. D. Blystone, E. J. Brown, and W. A. Frazier. 1996. Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin. J. Biol. Chem. 271:21.
28. Bornstein, P. 1992. Thrombospondins: structure and regulation of expression. FASEB J. 6:3290.
29. Lahav, J. 1993. The functions of thrombospondin and its involvement in physiology and pathophysiology. Biochim. Biophys. Acta 1182:1.
30. Hermann, P., M. Rubio, T. Nakajima, G. Delespesse, and M. Sarfati. 1998. IFN-α priming of human monocytes differentially regulates gram-positive and gram-negative bacteria-induced IL-10 release and selectively enhances IL-12p70, CD80, and MHC class 1 expression. J. Immunol. 161:2011.
31. Ohshima, Y., and G. Delespesse. 1997. T cell-derived 1L-4 and dendritic cell-derived IL-12 regulate the lymphokine-producing phenotype of alloantigen-primed naive human CD4 T cells. J. Immunol. 158:629.
32. Armant, M., M. Ruhio, G. Delespesse, and M. Sarfati. 1995. Soluble CD23 directly activates monocytes to contribute to the antigen-independent stimulation of resting T cells. J. Immunol. 155:4868.
33. Zhou, M., and E. J. Brown. 1993. Leukocyte response integrin and integrin-associated protein act as a signal transduction unit in generation of a phagocyte respiratory burst. J. Exp. Med. 178:1165.
34. Brown, E., L. Hooper, T. Ho, and H. Gresham. 1990. Integrin-associated protein: a 50-kD plasma membrane antigen physically and functionally associated with integrins. J. Cell Biol. 111:2785.
35. Snijders, A., C. M. U. Hilkens, P. Kalinski, and M. L. Kapsenberg. 1998. High levels of IL-12 production by human dendritic cellsrequires two signals. Int. Immunol. 10:1593.
36. 5 and CD36, and cross-present antigens to cytotoxic T lymphocytes. J. Exp. Med. 188:1359.
37. Savill, J., I. Dransfield, N. Hogg, and C. Haslett. 1990. Vitronectin receptor-mediated phagocytosis of cells undergoing apoptosis. Nature 343:170.
38. 2, promote type 2 cytokine production in maturing human naive T helper cells. J. Immunol. 159:28.
39. Karp, C. L., M. Wysocka, X. Ma. M. Marovich, R. E. Factor, T. Nutman, M. Armant. L. Wahl, P. Cuomo, and G. Trinchieri. 1998. Potent suppression of IL-12 production from monocytes and dendritic cells during endotoxin tolerance. Eur. J. Immunol. 28:3128.
40. 2. Blood 91:3112.
41. Kalinski, P., J. H. N. Schuitemaker, C. M. U. Hilkens, E. A. Amsterdam, and M. L. Kapsenberg. 1999. Final maturation of human dendritic cells is associated with decreased responsiveness to IFN-γ and to bacterial IL-12 inducers: decreased ability of mature dendritic cells to produce IL-12 during interaction with T helper cells. J. Immunol. 163:3231.
42. Cella, M., D. Scheidegger, K. Palmer-Lehmann, P. Lane, A. Lanzavecchia, and G. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184:747.
43. Stoll, S., H. Jonuleit, E. Schmitt, G. Müller, H. Yamauchi, M. Kurimoto, J. Knop, and A. H. Enk. 1998. Production of functional IL-18 by different subtypes of murine and human dendritic cells (DC): DC-derived IL-18 enhances IL-12-dependent Th1 development. Eur. J. Immunol. 28:3231.
44. + T cells: modulation by interleukin-4 and interleukin-12. Eur. J. Immunol. 26:571.
45. Urban, B. C., D. J. P. Ferguson, A. Pain, N. Willcox, M. Plebanski, J. M. Austyn, and D. J. Roberts. 1999. Plasmodium falciparum-infected erythrocytes modulate the maturation of dendritic cells. Nature 400:73.
46. Robson, K. J. H., U. Frevert, I. Reckmann, G. Cowan, J. Beier, I. G. Scragg, K. Takehara, D. H. L. Bishop, G. Pradel, R. Sinden, S. Saccheo, H.-M. Müllier, and A. Crisanti. 1995. Thrombospondin-related adhesive protein (TRAP) of Plasmodium falciparum: expression during sporozoite ontogeny and binding to human hepalocytes. EMBO J. 14:3883.
47. Schultz-Cherry, S., J. Lawler, and J. E. Murphy-Ullrich. 1994. The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-β J. Biol. Chem. 269:26783.
48. Crawford, S. E., V. Stellmach, J. E. Murphy-Ullrich, S. M. F. Ribeiro, J. Lawler, R. O. Hynes, G. P. Boivin, and N. Bouck. 1998. Thrombospondin-1 is a major activator of TGF-β1 in vivo. Cell 93:1159.
49. Armant, M., M.-N. Avice, P. Hermann, M. Rubio, G. Delespesse, and M. Sarfati. 1999. CD47 selectively downregulates human IL-12 production and responsiveness. J. Exp. Med. 190:1175.