A peptide mimic of E-selectin ligand inhibits sialyl Lewis X-dependent lung colonization of tumor cells

Cancer Research

Volumn 60, Issue 2, 2000, Pages 450-456

  Fukuda, Michiko N ^a   Ohyama, Chikara ^a,c   Lowitz, Kevin ^a   Matsuo, Osamu ^b   Pasqualini, Renata ^a   Ruoslahti, Erkki ^a   Fukuda, Minoru ^a  

^a BURNHAM INSTITUTE   (United States)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BREVICAN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; OLIGOSACCHARIDE; PADGEM PROTEIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LUNG METASTASIS; METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ISOLATION; TUMOR CELL;

ANIMALS; CELL ADHESION; E-SELECTIN; HL-60 CELLS; HUMANS; LECTINS, C-TYPE; LEWIS BLOOD-GROUP SYSTEM; LUNG; LUNG NEOPLASMS; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM METASTASIS; NERVE TISSUE PROTEINS; OLIGOPEPTIDES; OLIGOSACCHARIDES; PEPTIDE FRAGMENTS; PROTEOCHONDROITIN SULFATES; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

EID: 0034650484     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (57)

1. Feizi, T. Demonstration by monoclonal antibodies that carbohydrate structures of glycoproteins and glycolipids are onco-developmental antigens. Nature (Lond.), 314: 53-57, 1985.
2. Hakomori, S. Aberrant glycosylation in tumors and tumor-associated carbohydrate antigens. Adv. Cancer Res., 52: 257-331, 1989.
3. Fukuda, M. Possible roles of tumor-associated carbohydrate antigens. Cancer Res., 56: 2237-2244, 1996.
4. Fukuda, M., Spooncer, E., Oates, J. E., Dell, A., and Klock, J. C. Structure of sialylated fucosyl lactosaminoglycan isolated from human granulocytes. J. Biol. Chem., 259: 10925-10935, 1984.
5. Mizoguchi, A., Takasaki, S., Maeda, S., and Kobata, A. Changes in asparagine-linked sugar chains of human promyelocytic leukemic cells (HL-60) during monocytoid differentiation and myeloid differentiation. Decrease of high-molecular-weight oligosaccharides in acidic fraction. J. Biol. Chem., 259: 11949-11957, 1984.
6. Lowe, J. B., Stoolman, L. M., Nair, R. P., Larsen, R. D., Berhend, T. L., and Marks, R. M. ELAM-1-dependent cell adhesion to vascular endothelium determined by a transfected human fucosyltransferase cDNA. Cell, 93: 10925-10935, 1990.
7. X. Science (Washington DC), 250: 1130-1132, 1990.
8. X determinant on myeloid and tumor cells. Science (Washington DC), 250: 1132-1135, 1990.
9. X. Proc. Natl. Acad. Sci. USA, 88: 6224-6228, 1991.
10. Rosen, S. D., and Bertozzi, C. R. Leukocyte adhesion: two selectins converge on sulphate. Curr. Biol., 6: 261-264, 1996.
11. X, an L-selectin ligand displayed by CD34. Immunity, 11: 79-89, 1999.
12. Bistrup, A., Bhakta, S., Lee, J. K., Belov, Y. Y., Gunn, M. D., Zuo, F-R., Huang, C-C., Kannagi, R., Rosen, S. D., and Hemmerich, S. Sulfotransferase of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin. J. Cell Biol., 145: 899-910, 1999.
13. a antigens in human colorectal and pancreatic tissues. Cancer Res., 48: 3834-3842, 1988.
14. Fukushima, K., Hirota, M., Terasaki, P. I., Wakasaka, A., Togashi, H., Chia, D., Suyama, N., Fukushi, Y., Nudelman, E., and Hakomori, S-I. Characterization of sialylated Lewis X as a new tumor-associated antigen. Cancer Res. 44: 5279-5285, 1984.
15. Takada, A., Ohmori, K., Yoneda, T., Tsuyuoka, K., Hasegawa, A., Kiso, M., and Kannagi, R. Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer Res., 53: 354-361, 1993.
16. Fukushi, Y., Nudelman, E., Levery, S. B., Hakomori, S., and Rauvala, H. Novel fucolipids accumulating in human adenocarcinoma. III. A hybridoma antibody (FH6) defining a human cancer-associated difucoganglioside (VI3NeuAcV3III3 Fuc2nLc6). J. Biol. Chem. 259: 10511-10517, 1984.
17. X is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1. J. Biol. Chem., 266: 14869-14872, 1991.
18. Nakamori, S., Kameyama, M., Imaoka, S., Furukawa, H., Ishikawa, O., Sasaki, Y., Kabuto, T., Iwanaga, T., Matsushita, Y., and Irimura, T. Increased expression of sialyl Lewis X antigen correlates with poor survival in patients with colorectal carcinoma: clinicopathological and immunohistochemical study. Cancer Res., 53: 3632-3637, 1993.
19. Shimodaira, K., Nakayama, J., Nakamura, N., Hasebe, O., Katsuyama, T., and Fukuda, M. Carcinoma-associated expression of core 2 β-1,6-N-acetylglucosaminyl-transferase gene in human colorectal cancer: role of O-glycans in tumor progression. Cancer Res., 57: 5201-5206, 1997.
20. Sawada, R., Tsuboi, S., and Fukuda, M. Differential E-selectin dependent adhesion efficiency in sublines of a human colon cancer exhibiting distinct metastatic potentials. J. Biol. Chem., 269: 1425-1431, 1994.
21. Martin-Satué, M., Marrugat, R., Cancelas, J. A., and Blanco, J. Enhanced expression of α(1,3)-fucosyltransferase genes correlates with E-selectin-mediated adhesion and metastatic potential of human lung adenocarcinoma cells. Cancer Res., 58: 1544-1550, 1998.
22. Ohyama, C., Tsuboi, S., and Fukuda, M. Dual roles of sialyl Lewis X oligosaccharides in tumor metastasis and rejection by natural killer cells. EMBO J., 18: 1516-1525, 1999.
23. Martin-Satué, M., de Castellarnau, C., and Blanco, J. Overexpression of α(1,3)-fucosyltransferase VII is sufficient for the acquisition of lung colonization phenotype in human lung adenocarcinoma HAL-24Luc cells. Br. J. Cancer, 80: 1169-1174, 1999.
24. Mulligan, M. S., Lowe, J. B., Larsen, R. D., Paulson, J., Zheng, Z. L., DeFrees, S., Maemura, K., Fukuda, M., and Ward, P. A. Protective effects of sialylated oligosaccharides in immune complex-induced acute lung injury. J. Exp. Med., 178: 623-631, 1993.
25. Mulligan, M. S., Paulson, J. C., De Frees, S., Zheng, Z. L., Lowe, J. B., and Ward, P. A. Protective effects of oligosaccharides in P-selectin-dependent lung injury. Nature (Lond.), 364: 149-151, 1993.
26. Buerke, M., Weyrich, A. S., Zheng, Z., Gaeta, F. C., Forrest, M. J., and Lefer, A. M. Sialyl Lewis X-containing oligosaccharide attenuates myocardial reperfusion injury in cats. J. Clin. Invest., 93: 1140-1148, 1994.
27. Koivunen, E., Wang, B., and Ruoslahti, E. Isolation of a highly specific ligand for the α5β1 integrin from a phage display library. J. Cell Biol., 124: 373-380, 1994.
28. Healy, J. M., Murayama, O., Maeda, T., Yoshino, K., Sekiguchi, K., and Kikuchi, M. Peptide ligands for integrin αvβ3 selected from random phage display libraries. Biochemistry, 34: 3948-3955, 1995.
29. Pasqualini, R., and Ruoslahti, E. Organ targeting in vivo using phage display peptide libraries. Nature (Lond.), 380: 364-366, 1996.
30. Hoess, R., Brinkmann, U., Handel, T., and Pastan, I. Identification of a peptide which binds to the carbohydrate-specific monoclonal antibody B3. Gene, 128: 43-49, 1993.
31. Ishikawa, D., Kikkawa, H., Ogino, K., Hirabayashi, Y., Oku, N., Taki, T. GD1α-replica peptides functionally mimic GD1α, an adhesion molecule of metastic tumor cells, and suppress the tumor metastasis. FEBS Lett., 441: 20-24, 1998.
32. Scott, J. K., and Smith, G. P. Searching for peptide ligands with an epitope library. Science (Washington DC), 249: 386-390, 1990.
33. Aruffo, A., Kolanus, W., Walz, G., Fredman, P., and Seed, B. CD62/P-selection recognition of myeloid and tumor cell sulfatides. Cell, 67: 35-44, 1991.
34. Sueyoshi, S., Tsuboi, S., Sawada-Hirai, R., Dang, U. N., Lowe, J. B., and Fukuda, M. Expression of distinct fucosylated oligosaccharides and carbohydrate-mediated adhesion efficiency directed by two different α-1,3-fucosyltransferases. Comparison of E- and L-selectin-mediated adhesion. J. Biol. Chem., 269: 32342-32350, 1994.
35. X expressed on the cell surface supports L-selectin-mediated adhesion. J. Biol. Chem., 271: 27213-27216, 1996.
36. Tsuboi, S., and Fukuda, M. Branched O-linked oligosaccharides ectopically expressed in transgenic mice reduce primary T-cell immune responses. EMBO J., 16: 6364-6373, 1997.
37. Miura, R., Aspberg, A., Ethell, I. M., Hagihara, K., Schnaar, R. L., Ruoslahti, E., and Yamaguchi, Y. The proteoglycan lectin domain binds sulfated cell surface glycolipids and promotes cell adhesion. J. Biol. Chem., 274: 11431-11438, 1999.
38. Weitz-Schmidt, G., Stokmaier, D., Scheel, C., Nifant'ev, N. E., Tuzikov, A. B., and Bovin, N. V. An E-selectin binding assay based on a polyacrylamide-type glycoconjugate. Anal. Biochem., 238: 184-190, 1996.
39. Kukowska-Latallo, J. F., Larsen, R. D., Nair, R. P., and Lowe, J. B. A cloned human cDNA determines expression of a mouse stage-specific embryonic antigen and the Lewis blood group α(1,3/1,4)fucosyltransferase. Genes Dev., 4: 1288-1303, 1990.
40. X (defined by Mab FH6) and LCP. Clin. Exp. Metastasis. 9: 245-257, 1991.
41. Martens, C. L., Cwirla, S. E., Lee, R. Y., Whitehorn, E., Chen, E. Y-F., Bakker, A., Martin, E. L., Wangstrom, C., Gopalan, P., Smith, C. W., Tate, E., Koller, K. J., Schatz, P. J., Dower, W. J., and Barrett, R. W. Peptides which bind to E-selectin and block neutrophil adhesion. J. Biol. Chem., 270: 21129-21136, 1995.
42. Nelson, R. M., Dolich, S., Aruffo, A., Cecconi, O., and Bevilacqua, M. P. Higher-affinity oligosaccharide ligands for E-selectin. J. Clin. Invest., 91: 1157-1166, 1993.
43. X: potent inhibitors of E-selectin-mediated cell adhesion; reagent for staining activated endothelial cells. Glycobiology, 4: 259-265, 1994.
44. Harris, S. L., Craig, L., Methroke, J. S., Rashed, M., Zwick, M. B., Kenar, K., Toone, E. J., Greenspan, N., Auzanneau, F. I., Marino-Albernas, J-R., Pinto, M. B., and Scoot, J. K. Exploring the basis of peptide-carbohydrate crossreactivity: evidence for discrimination by peptides between closely related anti-carbohydrate antibodies. Proc. Natl. Acad. Sci. USA, 94: 2454-2459, 1997.
45. Taki, T., Ishikawa, D., Hamasaki, H., and Handa, S. Preparation of peptides which mimic glycosphingolipids by using phage petide library and their modulation on β-galactosidase activity. FEBS Lett., 418: 219-223, 1997.
46. Y immune responses in rabbits and mice. J. Pept. Res., 53: 252-260, 1999.
47. Hanjan, S. N., Kearney, J. F., and Cooper, M. D. A monoclonal antibody (MMA) that identifies a differentiation antigen on human myelomonocytic cells. Clin. Immunol. Immunopathol., 23: 172-188, 1982.
48. Magnani, J. L., Ball, E. D., Fanger, M. W., Hakomori, S. I., and Ginsburg, V. Monoclonal antibodies PMN 6, PMN 29, and PM-81 bind differently to glycolipids containing a sugar sequence occurring in lacto-N-fucopentaose III. Arch. Biochem. Biophys., 233: 501-506, 1984.
49. Gooi, H. C., Feizi, T., Kapadia, A., Knowles, B. B., Solter, D., and Evans, M. J. Stage-specific embryonic antigen involves α1 goes to 3 fucosylated type 2 blood group chains. Nature (Lond.), 292: 156-158, 1981.
50. X oligosaccharide. J. Cell Biol., 117: 895-902, 1992.
51. Kansas, G. S. Selectins and their ligands: current concepts and controversies. Blood, 88: 3259-3287, 1996.
52. X carbohydrate antigen: liver colonization and adhesion to vascular endothelial cells. Exp. Cell Res., 216: 215-221, 1995.
53. a in lesions of breast carcinoma. Int. J. Cancer, 74: 296-300, 1997.
54. Khatib, A-M., Kontogiannea, M., Fallavollita, L., Jamison, B., Meterissian, S., and Brodt, P. Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells. Cancer Res., 59: 1356-1361, 1999.
55. a. Int. J. Oncol., 6: 773-781, 1995.
56. Matsumoto, N., Ribaudo, R. K., Abastado, J-P., Margulies, D. H., and Yokoyama, W. M. The lectin-like NK cell receptor Ly-49A recognizes a carhohydrate-independentepitpoe on its MHC class I ligand. Immunity, 8: 245-254, 1998.
57. 4-4-GalNAcβ1,4GlcNAcβ or Man at independent sites. Proc. Natl. Acad. Sci. USA, 94: 11256-11261, 1997.