Effects of cholinergic agents on spontaneous activity of nucleus basalis magnocellularis neurons in different age rats

Neuroscience Letters

Volumn 288, Issue 2, 2000, Pages 91-94

  Zhang, Yu Qiu ^a   Ji, Ya Ping ^b   Mei, Jun ^b  

^a FUDAN UNIVERSITY   (China)

^b XI'AN MEDICAL UNIVERSITY   (China)

Author keywords

Acetylcholine; Aging; Atropine; Cholinergic agents; Nucleus basalis of Magnocellularis; Spontaneous firing; Tubocurarine

Indexed keywords

ACETYLCHOLINE; ATROPINE; CHOLINERGIC RECEPTOR STIMULATING AGENT; TUBOCURARINE CHLORIDE;

AGE; AGED; AGING; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; FEMALE; MAGNOCELLULAR NUCLEUS; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE UNIT ACTIVITY;

ACETYLCHOLINE; AGING; ANIMALS; ATROPINE; BASAL NUCLEUS OF MEYNERT; CHOLINERGIC AGENTS; ELECTROPHYSIOLOGY; FEMALE; INJECTIONS, INTRAVENTRICULAR; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; TUBOCURARINE;

EID: 0034648114     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(00)01186-1     Document Type: Article

References (16)

1. Abe K., Inokawa M., Kashiwagi A., Yangihara T. Amnesia after a discrete basal forebrain lesion. J. Neurol. Neurosurg. Psychiatry. 65:1998;126-130.
2. Baxter M.G., Bucci D.J., Gorman L.K., Wiley R.G., Gallagher M. Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in rat. Behav. Neurosci. 109:1995;714-722.
3. Dekker A.J.A.M., Connor D.J., Thal L.J. The role of cholinergic projections from the nucleus basalis in memory. Neurosci. Biobehav. Rev. 15:1991;299-317.
4. Détári L., Rasmusson D.D., Semba K. The role of basal forebrain neurons in tonic and phasic activation of the cerebral cortex. Prog. Neurobiol. 58:1999;249-277.
5. Ezrin-Waters C., Resch L. The nucleus basalis of Meynert. Can. J. Neurol. Sci. 13:1986;8-14.
6. Fadel J., Sarter M., Bruno J.P. Age-related attenuation of stimulated cortical acetylcholine release in basal forebrain-lesioned rats. Neuroscience. 90:1999;793-802.
7. Lamour Y., Dutar P., Rascol O., Jobert A. Basal forebrain neurons projecting to the rat frontoparietal cortex: electrophysiological and pharmacological properties. Brain Res. 362:1986;122-131.
8. Mesulam M.M., Mufson E.J., Levey A.I., Wainer B.H. Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry. Neuroscience. 12:1984;669-686.
9. 2 receptors, interactions with amyloid metabolism, and perturbations of cortical plasticity. J. Physiol. Paris. 92:1998;293-298.
10. Muir J.L. Acetylcholine, aging, and Alzhemer's disease, Pharmacol. Biochem. Behav. 56:1997;687-696.
11. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd edn. 1986;Academic Press, Sydney.
12. Smiley J.F., Mesulam M.M. Cholinergic neurons of the nucleus basalis of Meynert receive cholinergic, catecholaminergic and GABAergic synapses: an electron microscopic investigation in the monkey, Neuroscience. 88:1999;241-255.
13. Smith M.L., Booze R.M. Cholinergic and GABAergic neurons in the nucleus basalis region of young and aged rats. Neuroscience. 87:1995;679-688.
14. Vilaro M.T., Palacios J.M., Mengod G. Multiplicity of muscarinic autoreceptor subtypes? Comparison of the distribution of cholinergic cells and cells containing mRNA for five subtypes of muscarinic receptors in the rat brain, Brain Res. Mol. Brain Res. 21:1994;30-46.
15. Wellman C.L., Sengelaub D.R. Cortical neuroanatomical correlates of behavioral deficits produced by lesion of the basal forebrain in rats. Behav. Neural. Biol. 56:1991;1-24.
16. Zhang Y.Q., Mei J. Neurophysiological alterations in nucleus basalis of magnocellularis neurons in aged rats. Chin. J. Neurosci. 2000;. (in press).