Evidence that ginsenosides prevent the development of opioid tolerance at the central nervous system

Life Sciences

Volumn 67, Issue 8, 2000, Pages 969-975

  Choi, Seok ^a   Jung, Se Yeon ^a   Rhim, Hyewhon ^b   Jeong, Soon Wuk ^a   Lee, Sang Mok ^c   Nah, Seung Yeol ^a  

^a Chonnam National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Konkuk University   (South Korea)

Author keywords

Analgesia; Ginsenosides; Opioid; Pain; Spinal cord; Tolerance

Indexed keywords

GINSENOSIDE; MORPHINE; OPIATE;

ANALGESIA; ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG TOLERANCE; MALE; NONHUMAN; RAT; SPINAL CORD; TAIL FLICK TEST;

ANALGESICS, OPIOID; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; GINSENOSIDES; MALE; MORPHINE; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS; SPINAL CORD;

EID: 0034647590     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(00)00682-2     Document Type: Article

References (17)

1. T. Kaku, T. Miyata, T. Uruno, I. Sako and A. Kinoshita, Arzneim Forsch. 25 343-347 (1975).
2. H.N. Bhargava and P. Ramarao, Gen. Pharmac. 22 521-525 (1991).
3. H.S. Kim, S.H. Shin, K.J. Choi and S.C. Kim, Korean J Ginseng Sci. 11 123-129 (1987).
4. H.S. Kim, K.W. Oh and Y.H. Seong, Korean J. Ginseng Sci. 15 179-182 (1991).
5. J. Watanabe, M. Takahashi and H. Kaneto, J. Pharmacobio-Dyn. 11 744-748 (1988).
6. J.S. Mogil, Y.S. Shin, E.W. McCleskey, S.C. Kim and S.Y. Nah, Brain Res. 792 218-228 (1998).
7. S.R. Yoon, J.J. Nah, Y.H. Shin, S.K. Kim, K.Y. Nam, H.S. Choi and S.Y. Nah, Life Sci. 62 PL319-PL325 (1998).
8. J.J. Nah, S. Choi, Y.H. Kim, S.C. Kim, K.Y. Nam, J.K. Kim and S.Y. Nah, J. Ginseng Sci. 23 38-43 (1999).
9. T.L. Yaksh, R.L. Kohl and T.A. Rudy, Eur. J. Pharmacol. 42 275-284 (1977).
10. P.R. Bromage, E. Camporesi and D. Chestnut, Anesth. Analg. 59 473-480 (1980).
11. T.L. Yaksh and T.A. Rudy, Physiol. Behav. 7 1302-1306 (1976).
12. F.E. D'Amour and D.L. Smith, J. Pharmacol. Exp. Ther. 72 74-79 (1941).
13. P. Ramarao and H.N. Bhargava, Gen. Pharmac. 21 877-880 (1990).
14. H.S. Kim, C.G. Jang and M.K. Lee, Planta Medica 56 158-163 (1990).
15. H.S. Kim, K.W. Oh, Y.H. Seong and K.J. Choi, Korean J. Ginseng Sci. 15 6-12 (1991).
16. H.S. Kim, K.W. Oh, H.M. Rheu and S.H. Kim, Pharmacol. Biochem. Behav. 42 587-593 (1992).
17. H.W. Suh, D.K. Song and Y.H. Kim, Gen. Pharmac. 29 873-877 (1997).