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This strategy could be considered ecologically compatible as in this approach the only molecule which undergoes chemical destruction is the ascorbic acid. No selenium-containing compound is produced as byproduct. Moreover, organoselenium compounds are known to be less toxic than their inorganic counterparts. Aromatic selenium compounds seems to be still less toxic than aliphatic selenium compounds. For detailed toxicological data on selenium compounds see: In Selenium; Zingaro, R. A., Cooper, C. W., Ed.; Van Nostrand Reinhold Company: New York, 1974; p 669.
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(b) For a modified synthesis, see: reference 14b.
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-
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